Tag:

diagnosis

Movement Disorders
Identifying kinematic biomarkers of the dystrophic phenotype in a zebrafish model of Duchenne muscular dystrophy

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Kinematic Biomarkers Identification Identifying kinematic biomarkers in the context of Duchenne muscular dystrophy (DMD) is …

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Headaches
Observational quality control study: insourcing multi-PCR-impact on the use of anti-infectives for patients with pleocytosis

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The study investigates the effects of transitioning to an insourced multi-polymerase chain reaction …

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Traumatic brain injury
High-definition transcranial direct current stimulation improved dynamic postural control in patients with concussion: A randomised crossover trial

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The investigation aimed to evaluate the impact of high-definition transcranial direct current stimulation …

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Traumatic brain injury
High-definition transcranial direct current stimulation improved dynamic postural control in patients with concussion: A randomised crossover trial

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview This research aimed to investigate the effects of high-definition transcranial direct current stimulation …

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Traumatic brain injury
Impact of anticoagulant therapy on delayed intracranial haemorrhage after traumatic brain injury: A study on the role of repeat CT scans and extended observation

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Background and Rationale Anticoagulant therapy is widely used in clinical practice to prevent thromboembolic events, …

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Functional neurological disorders
Neuroglobin: A promising candidate to treat neurological diseases

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Neuroglobin Functionality and Mechanism Neuroglobin, a heme-containing protein predominantly expressed in the brain, plays a …

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Dementia
Crossing the ‘Cookie Theft’ Corpus Chasm: Applying what BERT Learns from Outside Data to the ADReSS Challenge Dementia Detection Task

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Study Overview The study investigates the intersection between artificial intelligence and dementia detection by utilizing …

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Movement Disorders
Evaluation, Diagnosis, and Treatment of Concomitant Movement Disorders in Genetic Epilepsies

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Clinical Manifestations The manifestation of concomitant movement disorders in individuals with genetic epilepsies can vary …

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Traumatic brain injury
Impact of anticoagulant therapy on delayed intracranial haemorrhage after traumatic brain injury: A study on the role of repeat CT scans and extended observation

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Study Overview This study investigates the implications of anticoagulant therapy on the risk of delayed …

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Traumatic brain injury
Sex-stratified patterns in geriatric patients with mild traumatic brain injury and intracranial bleeding: a retrospective cohort study

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Background Information Mild traumatic brain injury (mTBI) presents a significant public health challenge, particularly among …

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The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)
Blast-induced mild traumatic brain injury (mTBI) occurs when shock waves travel through blood vessels and cerebrospinal fluid, leading to cerebral demyelination, which results in cognitive impairments and neuropsychiatric issues that impact quality of life. This study aims to evaluate myelin changes in white matter in mice with mTBI induced by an open-field low-intensity blast (LIB) […]