Tag:

diagnostic accuracy

Traumatic brain injury
EEG-based brain biomarker supports hyperbaric oxygen therapy for acute concussions

by myneuronews August 17, 2025

by myneuronews August 17, 2025

Brain Biomarkers and Concussions Recent advances in neuroscience have highlighted the significance of brain biomarkers …

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Headaches
Interpretable Machine Learning Integrates Multi-Source Biomarkers for Osteoarthritis Diagnosis and Mechanistic Insights: A Temporomandibular Joint Model

by myneuronews August 16, 2025

by myneuronews August 16, 2025

Study Overview This research explores the integration of diverse biomarkers through interpretable machine learning techniques …

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Traumatic brain injury
Functional hearing difficulties in Veterans with blast and blunt head trauma are associated with reduced fractional anisotropy in putative auditory radiations

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Study Overview This research investigates the relationship between hearing difficulties and changes in brain structure …

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Dementia
Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Pathological Roles of Tmem106b in Neurodegeneration The involvement of TMEM106B in neurodegenerative diseases is a …

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Traumatic brain injury
Ultra-early detection of S100B biomarkers using a nanophotonic biosensor with deep learning quantification: A clinical model based on EDAS patients

by myneuronews August 2, 2025

by myneuronews August 2, 2025

Detection Mechanisms The detection of S100B biomarkers hinges upon advanced methodologies that leverage both nanotechnology …

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Traumatic brain injury
VOMS Baseline Versus Postinjury: A Comparison of a Standardized Novel Prototype and a Virtual Reality Application in Sport-Related Concussion

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Study Overview This research focuses on evaluating two different methods for assessing vestibular-ocular-motor function in …

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Traumatic brain injury
Post-Concussion Syndrome and Functional Neurological Disorder: Diagnostic Interfaces, Risk Mechanisms, and the Functional Overlay Model

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Understanding Post-Concussion Syndrome Post-concussion syndrome (PCS) represents a complex array of symptoms that may arise …

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Headaches
Case Report: Advanced breast invasive ductal carcinoma with erysipeloid cutaneous metastasis misdiagnosed as erysipelas

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Case Presentation A 56-year-old female presented with a complex medical history that ultimately led to …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Traumatic brain injury
Multivariate Base Rates of Standard- and Skyline-Cutoff Elevations on the Personality Assessment Inventory: Do They Distinguish Simulated from Genuine PTSD?

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Study Overview This study investigates the effectiveness of specific cutoff elevations on the Personality Assessment …

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Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia
Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia…
Are symptoms clustered into latent classes in pediatric functional neurological disorder?
Symptoms Clustering in Pediatric Functional Neurological Disorder Pediatric functional neurological disorder (FND) presents a complex…
An e-Delphi approach to develop a patient-reported outcome measure to assess functional/dissociative seizures severity
Study Overview In recent years, the growing recognition of the impact of functional/dissociative seizures on…
Diagnostic challenges in Burkitt’s lymphoma with skull base and paravertebral involvement, and hearing loss: a case report
Study Overview This case report focuses on Burkitt’s lymphoma, a highly aggressive type of non-Hodgkin…
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of…

Hyperphosphorylated tau and amyloid-beta proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository
BackgroundThe Lieber Institute for Brain Development (LIBD) has one of the largest postmortem human brain banks for the study of neuropsychiatric disorders in the world. The postmortem evaluation involves neuropathological assessment for age-related protein accumulations, specifically phosphorylated tau (p-tau) and amyloid-β (Aβ).ObjectivePresent the LIBD semiquantitative assessment methodology for p-tau and Aβ by comparing proteinopathy by […]
Leveraging the Enhanced Sports as a Laboratory Assessment Model to Cross-Validate a Formula Used to Predict Clinical Recovery From Concussion in Collegiate Athletes
CONCLUSIONS: Upon cross-validation, our prognostic formula had limited sensitivity and specificity when predicting clinical recovery after concussion. This formula may be used, with caution, when accompanied by a multidimensional assessment to inform clinical decision making after concussion.
Commentary: Mechanisms of Concussions Among High School Athletes in School-Sponsored Sports: Implications for Safety
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This case report describes the clinical response and safety of intranasal esketamine (Spravato®) in a 61-year-old female with treatment-resistant depression (TRD), a history of electroconvulsive therapy (ECT) poor response, and structural brain abnormalities secondary to left frontal lobe tissue loss from traumatic brain injury in 2008. Despite multiple antidepressant trials, atypical antipsychotic augmentation, and 6 […]
Ocular Motor Control and Cognitive Function in Military Veterans With Chronic Mild Traumatic Brain Injury
CONCLUSIONS: Results support the conclusion that OMC and cognitive performance are persistent co-occurring problems in Veterans with chronic mTBI. Notably, these deficits can be detected even after as few as 2 mTBIs that occurred 11 years earlier, indicating that an OMC-cognition axis of sequelae may exist in the chronic stage of mTBI. The results also […]