Tag:

diagnostic accuracy

Functional neurological disorders
Gene replacement therapy to restore polyamine metabolism in a Snyder-Robinson syndrome mouse model

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Restoration of Polyamine Metabolism The restoration of polyamine metabolism represents a pivotal intervention in the …

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Functional neurological disorders
Unveiling diverse clinical symptom patterns and neural activity profiles in major depressive disorder subtypes

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Symptom Patterns in Major Depressive Disorder In the realm of mental health, Major Depressive …

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Movement Disorders
Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Research Objectives The primary aim of this study is to explore the relationship between fluctuations …

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Functional neurological disorders
Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Understanding Mild Cognitive Impairment Heterogeneity Mild cognitive impairment (MCI) is a clinical condition that marks …

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Functional neurological disorders
In-silico analysis of deleterious non-synonymous SNPs in the human AVPR1a gene linked to autism

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Significance of AVPR1a Gene in Autism The AVPR1a gene, which encodes the arginine vasopressin receptor …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apolipoprotein C1 and Cognitive Decline The relationship between apolipoprotein C1 (APOC1) and cognitive …

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Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Traumatic brain injury
Correction: Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Cerebral haemodynamics in concussion Cerebral haemodynamics refers to the dynamics of blood flow within the …

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Headaches
Current Evidence in the Management of Central Skull Base Osteomyelitis: A Systematic Review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Study Overview Central Skull Base Osteomyelitis (CSBO) is a serious infection that affects the bony …

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Stroke
Multi-classification Deep Learning Approach for Diagnosing Stroke Type and Severity Using Multimodal Magnetic Resonance Images

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Study Overview The study investigates the application of deep learning techniques for diagnosing various types …

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Understanding factors influencing the return to physical activity, perspectives of adults with concussion/mild traumatic brain injury: A qualitative study
Understanding the factors that influence the return to physical activity can help to modify behaviour to enhance the recovery of symptoms and physical activity. We conducted 14 semi-structured interviews to explore the barriers and facilitators to returning to physical activity in adults following a mild traumatic brain injury (TBI). The study design was informed by […]
Clinical Utility of the Sport Concussion Office Assessment Tool 6 (SCOAT6) and Other Select Multidomain Assessments for Subacute Sport-Related Concussion
CONCLUSIONS: The PCSI, timed tandem gait, and mVOMS components of the SCOAT6 were useful in identifying sport-related concussion. However, verbal cognitive tests, orthostatic vital signs, and clinical balance components were not useful for this purpose. The CP Screen, additional items from the full version of the VOMS, and ImPACT memory and processing speed were also […]
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies
INTRODUCTION: Persistent post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) represents a growing global health challenge that significantly impacts patients' quality of life. Despite advances in acute concussion management, there remains a critical need for effective, evidence-based treatments for chronic PCS, as current interventions show limited success in addressing both symptoms and underlying pathophysiology.
Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.