Tag:

emotional regulation

Functional neurological disorders
Loneliness in Parkinson’s disease: Subjective experience overshadows objective motor impairment

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Understanding Loneliness in Parkinson’s Disease Loneliness is a profound and complex emotion that frequently accompanies …

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Traumatic brain injury
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury

by myneuronews May 15, 2025

by myneuronews May 15, 2025

TRPM3 Channel Function in the Brain The TRPM3 channel, a member of the transient receptor …

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Traumatic brain injury
Traumatic brain injury graphing: A case study of Charles Whitman

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Case Background In August 1966, Charles Whitman became infamous for a tragic shooting spree in …

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Functional neurological disorders
In-silico analysis of deleterious non-synonymous SNPs in the human AVPR1a gene linked to autism

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Significance of AVPR1a Gene in Autism The AVPR1a gene, which encodes the arginine vasopressin receptor …

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Traumatic brain injury
Changes in Coping Skills Throughout Concussion Recovery in College-Aged Individuals

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Coping Skills Assessment The evaluation of coping skills among college-aged individuals recovering from concussions is …

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Traumatic brain injury
Acute Changes in Sleep Stages Following Concussion in Collegiate Athletes: A Pilot Study

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Study Overview This pilot study investigates the immediate effects of concussion on the sleep patterns …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF’s Role in Depression Brain-derived neurotrophic factor (BDNF) is a protein that plays a …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological tau phosphorylation mechanisms Tau is a critical protein in the brain, primarily known for …

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Traumatic brain injury
A systematic review and meta-analysis of sleep following mild traumatic brain injury: A synthesis of the literature according to age and time-since-injury

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Overview of Sleep Disruptions Sleep disruptions represent a common and often underestimated consequence following mild …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.