Tag:

extracellular vesicles

Traumatic brain injury
Efficacy and safety of exosomes from Wharton’s Jelly-derived mesenchymal stem cells in traumatic brain injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Efficacy of exosomes Exosomes derived from Wharton’s Jelly mesenchymal stem cells (WJ-MSCs) have shown significant …

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Traumatic brain injury
Efficacy and safety of exosomes from Wharton’s Jelly-derived mesenchymal stem cells in traumatic brain injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This investigation focuses on the therapeutic potential of exosomes derived from Wharton’s Jelly …

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Traumatic brain injury
Non-Targeted Analysis of Extracellular Vesicle-Enriched Plasma Proteome Between Early and Late Rugby Playing Career

by myneuronews November 30, 2025

by myneuronews November 30, 2025

Study Overview This research investigates the differences in the proteomic profiles of extracellular vesicles (EVs) …

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Headaches
Neuron-derived extracellular vesicles reflect adaptive neuronal responses to cortical spreading depolarization: a biomarker study for migraine

by myneuronews November 26, 2025

by myneuronews November 26, 2025

Study Overview This study investigates the role of neuron-derived extracellular vesicles (EVs) in the context …

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Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Traumatic brain injury
Prophylactic Treatment with Amnion Progenitor Cell Secretome Mitigates Traumatic Optic Neuropathy

by myneuronews October 12, 2025

by myneuronews October 12, 2025

Study Overview The research focuses on the therapeutic potential of amnion progenitor cell secretome in …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

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Functional neurological disorders
Photoactivatable Exosenolytics Activate Natural Killer Cells for Delaying Osteoarthritis

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Mechanism of Photoactivatable Exosenolytics The study introduces photoactivatable exosenolytics as a novel therapeutic agent designed …

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Functional neurological disorders
Scar-associated macrophages and biliary epithelial cells interaction exacerbates hepatic fibrosis in biliary atresia

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Mechanisms of Macrophage and Epithelial Cell Interaction The interaction between macrophages and biliary epithelial cells …

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Occult spinal CSF leak: to patch or not to patch-a case-based update
Occult Spinal CSF Leak Mechanisms Occult spinal cerebrospinal fluid (CSF) leaks occur when there is…
Active music therapy reduces depressive symptoms and enhances sleep and daily-life autonomy in older adults
Study Overview The research investigated the impact of active music therapy on older adults, particularly…
Functional movement disorder mimicking oromandibular dyskinesia
Clinical Presentation and Symptoms Patients with functional movement disorder (FMD) that mimics oromandibular dyskinesia often…
Soft-voting classifier for outcome prediction in traumatic brain injury patients with clear consciousness: model development and error pattern analysis
Study Overview This study addresses a significant gap in the field of traumatic brain injury…
Chronic dynamic behavioral changes and upregulation of glutamatergic signaling proteins following traumatic brain injury in females
Study Overview Traumatic brain injury (TBI) presents a significant challenge in contemporary neuroscience, particularly concerning…

Alzheimer's Imaging Consortium
CONCLUSIONS: The importance of these results is multifaceted. First, we defined a direct neural read-out of hippocampal activity in MEG that can index memory processes known to be affected in AD pathology. Second, we demonstrated the relationship between two complementary measures of hippocampal engagement (fMRI pattern separation, MEG repetition suppression) and their association to lure […]
Developing Topics
CONCLUSION: In this sample of 3,968 former American football players, findings support a dose-response relationship between football play and cognitive and neuropsychiatric function.
Alzheimer's Imaging Consortium
CONCLUSION: In a community-based cohort of older adults, TBI was associated with reductions in MRI hippocampal, frontal gray matter, and total cerebral gray matter volumes in females, but not males. Sex may portend different risk for later life atrophy after TBI, particularly in brain regions commonly affected by Alzheimer's disease and related dementias. Future work […]
Public Health
CONCLUSION: Findings highlight potential unique military risk factors for the development of cognitive impairment and dementia. These findings may help to inform future policy and develop interventions aimed at reducing long-term cognitive health consequences that may be associated with military service.
Developing Topics
CONCLUSION: In 2024 the lancet commission (Livingston 2024) reported the evidence was unclear whether menopause and HRT are causally related to dementia risk and suggested that TBI increases dementia risk. In this presentation we report the latest findings on the role of HRT in cognitive decline/dementia and the role of preventative interventions in those with […]