Tag:

extracellular vesicles

Headaches
Neuron-derived extracellular vesicles reflect adaptive neuronal responses to cortical spreading depolarization: a biomarker study for migraine

by myneuronews November 26, 2025

by myneuronews November 26, 2025

Study Overview This study investigates the role of neuron-derived extracellular vesicles (EVs) in the context …

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Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Traumatic brain injury
Prophylactic Treatment with Amnion Progenitor Cell Secretome Mitigates Traumatic Optic Neuropathy

by myneuronews October 12, 2025

by myneuronews October 12, 2025

Study Overview The research focuses on the therapeutic potential of amnion progenitor cell secretome in …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

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Functional neurological disorders
Photoactivatable Exosenolytics Activate Natural Killer Cells for Delaying Osteoarthritis

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Mechanism of Photoactivatable Exosenolytics The study introduces photoactivatable exosenolytics as a novel therapeutic agent designed …

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Functional neurological disorders
Scar-associated macrophages and biliary epithelial cells interaction exacerbates hepatic fibrosis in biliary atresia

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Mechanisms of Macrophage and Epithelial Cell Interaction The interaction between macrophages and biliary epithelial cells …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Non-Targeted Analysis of Extracellular Vesicle-Enriched Plasma Proteome Between Early and Late Rugby Playing Career
CONCLUSIONS AND CLINICAL RELEVANCE: Proteins associated with neuroprotection were specifically depleted in the plasma EV proteome of long-serving professional rugby players. The proteins highlighted in professional rugby players could be used to develop biomarker panels for predicting at-risk athletes or for guiding treatment interventions.
Rare "double tragedy" and successful salvage strategy after failed bilateral humeral fracture fixation in a resource-constrained setting: a case report
CONCLUSIONS: This case underscores the challenges of managing complex orthopaedic trauma in low-resource settings, where inadequate healthcare infrastructure, limited access to suitable implants, and insufficient health insurance coverage exacerbate treatment difficulties. The successful outcome in this case was achieved through staged treatment, collaboration with the patient, and the use of donated SIGN nails. The report […]
Does strengthening the cervical spine musculature enhance neck strength and reduce sports-related concussions in rugby and football players? A systematic literature review
CONCLUSION: The evidence in this systematic review suggests that the incorporation of CMS programs into rugby training may reduce concussion risk by almost half. However, further research is needed to evaluate the effectiveness of CMS in football and female rugby players.
Development and psychometric validation of a concussion symptom assessment tool for combat sports athletes
CONCLUSION: The COMBAT-PMS is a reliable, valid 23-item scale integrating physical and motivational concussion symptoms. It pioneers targeted assessment for combat sports, enabling early detection of head trauma impacts and challenging pain normalization to support safer athletic careers.
Symptoms of allodynia and pain thresholds amongst those with acute post-traumatic headache attributed to mild traumatic brain injury: a prospective, longitudinal study
No abstract