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extracellular vesicles

Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

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Functional neurological disorders
Photoactivatable Exosenolytics Activate Natural Killer Cells for Delaying Osteoarthritis

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Mechanism of Photoactivatable Exosenolytics The study introduces photoactivatable exosenolytics as a novel therapeutic agent designed …

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Functional neurological disorders
Scar-associated macrophages and biliary epithelial cells interaction exacerbates hepatic fibrosis in biliary atresia

by myneuronews May 18, 2025

by myneuronews May 18, 2025

Mechanisms of Macrophage and Epithelial Cell Interaction The interaction between macrophages and biliary epithelial cells …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]
Functional hearing difficulties in Veterans with blast and blunt head trauma are associated with reduced fractional anisotropy in putative auditory radiations
OBJECTIVES: Veterans of recent military conflicts have experienced a high rate of mild traumatic brain injury (mTBI) due to blast exposure. A debilitating symptom often reported by such patients is an impaired ability to perceive complex sounds (e.g., impaired speech comprehension in noisy environments). In a prior report, we found a continuous measure of historical […]
Clinical outcomes and quality of life after endovascular embolization for vein of Galen aneurysmal malformation (VGAM): a study from a low-and middle-income country
CONCLUSION: The long-term neurological outcomes of VGAM embolization remain variable. While staged embolization was significantly associated with outcomes, other factors may contribute. Larger studies are needed to determine the optimal approach for embolization to improve outcomes.
A Proof-of-Concept Development on Speech Analysis for Concussion Detection
Speech signal analysis to support objective clinical decision-making has gained immense interest, especially in neurological disorders. This research assessed the feasibility of speech analysis on the detection of concussions. Using a speech dataset from 82 concussed and 82 healthy participants, we extracted two speech feature sets focusing on Mel Frequency Cepstral Coefficients (MFCCs) to characterize […]

extracellular vesicles

Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

Photoactivatable Exosenolytics Activate Natural Killer Cells for Delaying Osteoarthritis

Scar-associated macrophages and biliary epithelial cells interaction exacerbates hepatic fibrosis in biliary atresia

Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis