Tag:

extracellular vesicles

Dementia
Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia

by myneuronews January 21, 2026

by myneuronews January 21, 2026

Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia …

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Dementia
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia

by myneuronews January 6, 2026

by myneuronews January 6, 2026

Study Overview The focus of this research is on exploring the potential of plasma extracellular …

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Traumatic brain injury
Efficacy and safety of exosomes from Wharton’s Jelly-derived mesenchymal stem cells in traumatic brain injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This investigation focuses on the therapeutic potential of exosomes derived from Wharton’s Jelly …

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Traumatic brain injury
Efficacy and safety of exosomes from Wharton’s Jelly-derived mesenchymal stem cells in traumatic brain injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Efficacy of exosomes Exosomes derived from Wharton’s Jelly mesenchymal stem cells (WJ-MSCs) have shown significant …

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Traumatic brain injury
Non-Targeted Analysis of Extracellular Vesicle-Enriched Plasma Proteome Between Early and Late Rugby Playing Career

by myneuronews November 30, 2025

by myneuronews November 30, 2025

Study Overview This research investigates the differences in the proteomic profiles of extracellular vesicles (EVs) …

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Headaches
Neuron-derived extracellular vesicles reflect adaptive neuronal responses to cortical spreading depolarization: a biomarker study for migraine

by myneuronews November 26, 2025

by myneuronews November 26, 2025

Study Overview This study investigates the role of neuron-derived extracellular vesicles (EVs) in the context …

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Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Traumatic brain injury
Prophylactic Treatment with Amnion Progenitor Cell Secretome Mitigates Traumatic Optic Neuropathy

by myneuronews October 12, 2025

by myneuronews October 12, 2025

Study Overview The research focuses on the therapeutic potential of amnion progenitor cell secretome in …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Biomarkers Traumatic brain injury
Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

by Ioannis Mavroudis November 16, 2024

by Ioannis Mavroudis November 16, 2024

Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia
Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia…
Are symptoms clustered into latent classes in pediatric functional neurological disorder?
Symptoms Clustering in Pediatric Functional Neurological Disorder Pediatric functional neurological disorder (FND) presents a complex…
An e-Delphi approach to develop a patient-reported outcome measure to assess functional/dissociative seizures severity
Study Overview In recent years, the growing recognition of the impact of functional/dissociative seizures on…
Diagnostic challenges in Burkitt’s lymphoma with skull base and paravertebral involvement, and hearing loss: a case report
Study Overview This case report focuses on Burkitt’s lymphoma, a highly aggressive type of non-Hodgkin…
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of…

Leveraging the Enhanced Sports as a Laboratory Assessment Model to Cross-Validate a Formula Used to Predict Clinical Recovery From Concussion in Collegiate Athletes
CONCLUSIONS: Upon cross-validation, our prognostic formula had limited sensitivity and specificity when predicting clinical recovery after concussion. This formula may be used, with caution, when accompanied by a multidimensional assessment to inform clinical decision making after concussion.
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This case report describes the clinical response and safety of intranasal esketamine (Spravato®) in a 61-year-old female with treatment-resistant depression (TRD), a history of electroconvulsive therapy (ECT) poor response, and structural brain abnormalities secondary to left frontal lobe tissue loss from traumatic brain injury in 2008. Despite multiple antidepressant trials, atypical antipsychotic augmentation, and 6 […]
Hyperphosphorylated tau and amyloid-beta proteinopathy in people over age 50: Findings from the Lieber Institute for Brain Development Brain Donation Repository
BackgroundThe Lieber Institute for Brain Development (LIBD) has one of the largest postmortem human brain banks for the study of neuropsychiatric disorders in the world. The postmortem evaluation involves neuropathological assessment for age-related protein accumulations, specifically phosphorylated tau (p-tau) and amyloid-β (Aβ).ObjectivePresent the LIBD semiquantitative assessment methodology for p-tau and Aβ by comparing proteinopathy by […]
Ocular Motor Control and Cognitive Function in Military Veterans With Chronic Mild Traumatic Brain Injury
CONCLUSIONS: Results support the conclusion that OMC and cognitive performance are persistent co-occurring problems in Veterans with chronic mTBI. Notably, these deficits can be detected even after as few as 2 mTBIs that occurred 11 years earlier, indicating that an OMC-cognition axis of sequelae may exist in the chronic stage of mTBI. The results also […]
Commentary: Mechanisms of Concussions Among High School Athletes in School-Sponsored Sports: Implications for Safety
No abstract