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FND

Functional neurological disorders
Biochemical investigation of pathogenic missense mutations of human 4-amino butyrate aminotransferase towards the understanding of the molecular pathogenesis of GABA transaminase deficiency

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Biochemical Characterization of Mutant 4-Aminobutyrate Aminotransferase In this detailed study, researchers focused on the biochemical …

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Functional neurological disorders
Comprehensive Neuropsychological Assessment of Confirmed Xeroderma Pigmentosum a Variant with Neurological Manifestations: Case Report

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Clinical Presentation and Symptoms The case of a patient with xeroderma pigmentosum (XP) confirmed the …

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Functional neurological disorders
Evidence of an unprecedented cytoplasmic function of DDX11, the Warsaw breakage syndrome DNA helicase, in regulating autophagy

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Cytoplasmic Role of DDX11 in Autophagy Recent research has unveiled a novel cytoplasmic function of …

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Functional neurological disorders
Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Neurodevelopmental Variants and Penetrance Neurodevelopmental copy number variants (CNVs) represent significant alterations in an individual’s …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Functional neurological disorders
Alterations of White Matter Functional Networks in Pediatric Drug-Resistant Temporal Lobe Epilepsy: A Graph Theory Analysis Study

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Alterations in White Matter Networks The study of white matter networks in pediatric patients suffering …

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Functional neurological disorders
A Narrative Review of Pemphigoid Diseases: Bridging Associations, Comorbidities, and Management

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Overview of Pemphigoid Diseases Pemphigoid diseases are a group of rare autoimmune conditions primarily characterized …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Material and Methods The study on fully biodegradable dendrimers as novel nanodrugs targeting amyloid-β-induced neurotoxicity …

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Functional neurological disorders
A narrative literature review of white matter microstructure in individuals at clinical high risk for psychosis

by myneuronews May 23, 2025

by myneuronews May 23, 2025

White Matter Microstructure and Psychosis Risk White matter microstructure plays a critical role in understanding …

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Functional neurological disorders
Fully biodegradable dendrimers as novel nanodrugs for amyloid-β-induced neurotoxicity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Biodegradable Dendrimers: A Novel Approach Dendrimers are highly branched molecules that can be customized at …

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The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury
CONCLUSION: HRV can be used as an independent predictor of unfavorable prognosis in patients with TBI. Including the SDNN index in prognostic models helps to effectively predict the prognosis of adult patients with TBI.
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D corticomimetic in vitro model of concussion was developed, confirming aldehyde production following impact. Total aldehyde levels were […]
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures
Service members and law enforcement personnel are frequently exposed to blast overpressure during training and combat due to the use of heavy weaponry such as large-caliber rifles, explosives, and ordnance. The cumulative effects of these repeated low-level (
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients
CONCLUSION: Evaluation of pediatric patients with head trauma together with these neuropeptides may provide great benefits in deciding whether to perform radiography such as CT. However, due to the relatively low sensitivities in ROC analysis and small sample size, further studies are warranted before they may be used as a screening test to distinguish CT-positive […]
Trajectories of fear avoidance behavior and recovery after mild traumatic brain injury: Findings from the Toronto Concussion Study
CONCLUSION: Early fear avoidance behavior often decreases, but when it does not, it is associated with worse recovery from mTBI. These findings may inform the timing and design of interventions targeting fear avoidance behavior in patients with mTBI. (PsycInfo Database Record (c) 2025 APA, all rights reserved).