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Functional neurological disorders

Functional neurological disorders
Identification and Functional Analysis of Cystathionine Beta-Synthase Gene Mutations in Chinese Families with Classical Homocystinuria

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Genetic Background of Homocystinuria Homocystinuria is a rare, inherited metabolic disorder primarily characterized by an …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Imbalanced goal-directed and habitual control in individuals with internet gaming disorder

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Internet Gaming Disorder Internet Gaming Disorder (IGD) has emerged as a significant concern in …

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Functional neurological disorders
Electroencephalographic aspects and phenotypic characteristics in children with autism

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Electroencephalographic Findings in Autism Electroencephalography (EEG) has become an essential tool in understanding the neurological …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomics Techniques in Glycine Receptor Analysis Understanding the complex interactions within neuronal proteins is critical …

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Functional neurological disorders
MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications-A Review

by myneuronews April 26, 2025

by myneuronews April 26, 2025

MTHFR Gene Polymorphisms and Their Role in Health The MTHFR gene, which stands for methylene …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomic Analysis of Glycine Receptors The detailed examination of glycine receptors (GlyRs) through proteomic analysis …

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Functional neurological disorders
MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications-A Review

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Clinical Significance of MTHFR Polymorphisms The MTHFR gene encodes the enzyme methylenetetrahydrofolate reductase, which plays …

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Functional neurological disorders
Striato-cortical connectivity patterns predict clinical profiles in Huntington’s disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Striato-Cortical Connectivity in Huntington’s Disease The study systematically examined the intricacies of striato-cortical connectivity in …

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Functional neurological disorders
Gut Neuropeptide Involvement in Parkinson’s Disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Gut Neuropeptides and Their Role in Neurodegeneration Gut neuropeptides are crucial biochemical messengers that play …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.