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Functional neurological disorders

Functional neurological disorders
Individualized psychotherapy reveals a very high prevalence of adverse life events in functional neurological disorders

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Prevalence of Adverse Life Events Recent findings indicate that individuals with functional neurological disorders (FND) …

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Functional neurological disorders
Individualized psychotherapy reveals a very high prevalence of adverse life events in functional neurological disorders

by myneuronews November 5, 2025

by myneuronews November 5, 2025

High Prevalence of Adverse Life Events Recent research highlights a striking correlation between functional neurological …

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Functional neurological disorders
Individualized psychotherapy reveals a very high prevalence of adverse life events in functional neurological disorders

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Prevalence of Adverse Life Events Recent studies have highlighted a striking and concerning relationship between …

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Functional neurological disorders
Psilocybin-Assisted Physiotherapy for Refractory Motor Functional Neurological Disorder: Protocol for a Randomised Dose-Comparison Pilot Study

by myneuronews November 4, 2025

by myneuronews November 4, 2025

Study Rationale The investigation into the therapeutic potential of psilocybin for treating refractory motor functional …

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Functional neurological disorders
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Longitudinal Gait Assessment In this study, gait patterns were assessed over a 12-month period to …

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Functional neurological disorders
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study

by myneuronews October 31, 2025

by myneuronews October 31, 2025

Longitudinal Gait Analysis Longitudinal gait analysis in the context of functional neurological disorders (FND) has …

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Functional neurological disorders
Functional Connectivity Gradients Reveal Altered Hierarchical Cortical Organization in Functional Neurological Disorder

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Functional Connectivity Patterns Recent investigations into the brain’s functional connectivity patterns have unveiled critical insights …

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Functional neurological disorders
Use of the Overcoming Functional Neurological Symptoms: A Five Areas Approach Workbook in a Therapist-Led Skills Group Format

by myneuronews October 29, 2025

by myneuronews October 29, 2025

Therapeutic Application of the Workbook The workbook “Overcoming Functional Neurological Symptoms: A Five Areas Approach” …

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Functional neurological disorders
Neurological Emergencies in Incarcerated Patients: Clinical Characteristics, Severity, and Outcomes in an Emergency Department with an Embedded Neuro-Emergency Expert Model

by myneuronews October 29, 2025

by myneuronews October 29, 2025

Neurological Presentations in Incarcerated Patients Incarcerated patients present a unique set of challenges when it …

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Functional neurological disorders
Neurological Emergencies in Incarcerated Patients: Clinical Characteristics, Severity, and Outcomes in an Emergency Department with an Embedded Neuro-Emergency Expert Model

by myneuronews October 29, 2025

by myneuronews October 29, 2025

Clinical Characteristics of Neurological Emergencies Neurological emergencies in incarcerated patients present a unique set of …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]