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Functional neurological disorders

Functional neurological disorders
Abnormal static and dynamic regional homogeneity in adolescent major depressive disorder with somatic symptoms: a resting-state fMRI study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Methodological Overview The study employs a resting-state functional magnetic resonance imaging (fMRI) approach to examine …

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Functional neurological disorders
Quantum magnetization exchange through transient hydrogen bond matrix defines magnetic resonance signal relaxation and anisotropy in central nervous system

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Quantum Magnetization Exchange Recent investigations have highlighted the significance of quantum magnetization exchange in the …

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Functional neurological disorders
What does a migraine aura look like?-A systematic review

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Migraine Aura Characteristics Migraine aura is a fascinating phenomenon that can manifest in various ways, …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Functional neurological disorders
Identification and Physiological Analysis of Novel Riboflavin Transporter RFVT

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Background of Riboflavin Transporters Riboflavin, also known as vitamin B2, is an essential nutrient that …

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Functional neurological disorders
Structural insights into heterohexameric assembly of epilepsy-related ligand-receptor complex LGI1-ADAM22

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Structural Characterization of LGI1-ADAM22 Complex The LGI1-ADAM22 complex plays a pivotal role in the synaptic …

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Functional neurological disorders
Static Plantar Pressure Distribution Measured Using PodoPrint Aluminum Platform in Multiple Sclerosis Patients: A Case-Control Study

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Static Plantar Pressure Analysis in Multiple Sclerosis Research into the static plantar pressure distribution in …

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Functional neurological disorders
Myeloproliferative syndrome as a cause of chorea

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Myeloproliferative Syndromes Overview Myeloproliferative syndromes (MPS) are hematologic disorders characterized by the excessive production of …

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Functional neurological disorders
Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Conformational Features of MMACHC The study delves into the conformational characteristics of MMACHC, a protein …

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Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]
Tackle characteristics associated with concussion in elite men's rugby union: unpicking the differences between tacklers and ball-carriers
CONCLUSIONS: Lower tackles reduce the chances of concussion to ball-carriers. The influence of tackle height on concussion to tacklers is more nuanced, but the chances are relatively low when contact is made with the ball-carrier's torso. These findings support ongoing implementation of strategies to reduce concussion risk by lowering tackle height to target the torso.
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model
Repetitive mild traumatic brain injury (rmTBI) is a major contributor to long-term neurological dysfunction, yet many preclinical models lack precise control and quantification of biomechanical forces across impacts. We developed a reproducible, closed-skull mouse model of rmTBI using a custom-built weight-drop apparatus featuring a solenoid-based rebound arrest system, integrated high-speed videography, and accelerometry to track […]
Pretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice
CONCLUSIONS: These results indicate that an anti-CGRP mAb can partially, but not fully, attenuate cephalic tactile hypersensitivity when administered immediately before or after the mTBI event. In contrast, a stronger rescue was seen when the anti-CGRP mAb was administered just prior to CGRP and nitric oxide triggers. Thus, depending on the timing of administration, the […]