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GCS

Traumatic brain injury
Repetitive Transcranial Magnetic Stimulation in Adolescents With Persistent Postconcussion Symptoms After Mild Traumatic Brain Injury: An Open Label Safety and Feasibility Study

by myneuronews December 17, 2025

by myneuronews December 17, 2025

Study Overview This study investigates the use of repetitive transcranial magnetic stimulation (rTMS) as a …

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Traumatic brain injury
A study on the association of apolipoprotein E with oxidative stress markers, neurological function, and cognitive impairment following traumatic brain injury

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Association of Apolipoprotein E and Oxidative Stress Apolipoprotein E (ApoE) plays a crucial role in …

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Traumatic brain injury
Patterns, severity, and outcomes of traumatic brain injury in a regional referral hospital in Kenya: a retrospective cohort study

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Patterns of Traumatic Brain Injury Traumatic brain injury (TBI) is a significant public health challenge, …

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Traumatic brain injury
Traumatic Brain Injury Across the Lifespan and in Conflict Zones

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Understanding Traumatic Brain Injury Traumatic Brain Injury (TBI) occurs when an external force causes damage …

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Traumatic brain injury
The Application of Lifestyle Medicine in Traumatic Brain Injury

by myneuronews December 8, 2025

by myneuronews December 8, 2025

Overview of Lifestyle Medicine Applications Lifestyle medicine encompasses a range of interventions aimed at improving …

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Traumatic brain injury
Traumatic brain injury outcomes and mortality predictors in Eastern India: An observational study

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Study Overview This observational study aimed to explore the outcomes of traumatic brain injury (TBI) …

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Traumatic brain injury
Traumatic brain injury outcomes and mortality predictors in Eastern India: An observational study

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Traumatic brain injury demographics The demographics of individuals experiencing traumatic brain injuries (TBIs) in Eastern …

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Traumatic brain injury
Interpreting the Hospital Anxiety and Depression Scale (HADS) for individuals with traumatic brain injury: Clinical correlates and empirical severity cutoffs

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Study Overview This study focuses on understanding the psychological impact of traumatic brain injury (TBI) …

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Traumatic brain injury
Effect of anticoagulation on isolated traumatic brain injury mortality using TQIP database: a propensity score analysis stratified by head injury severity

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Study Overview The analysis focuses on the impact of anticoagulation therapy on mortality rates in …

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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Kynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]