Tag:

genetic predisposition

Traumatic brain injury
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health …

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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

by myneuronews November 15, 2025

by myneuronews November 15, 2025

Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Design and Population The study utilized a robust multisite, multiancestry design, involving a comprehensive …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Summary The research conducted on functional seizure disorder within a diverse cohort of 675,680 …

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Headaches
Unexpected genomic architecture in a sporadic case of C1-INH Hereditary Angioedema: the hidden heritability

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Genomic Architecture Insights The genomic architecture in individuals with C1-INH Hereditary Angioedema (HAE) showcases a …

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Traumatic brain injury
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Overview of Posttraumatic Headache Posttraumatic headache (PTH) is a prevalent and often debilitating disorder that …

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Functional neurological disorders
Possible bimodality in the age distribution of pediatric functional neurological disorder

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Assessment of Age Distribution The investigation into the age distribution of pediatric functional neurological disorder …

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Traumatic brain injury
Post-Traumatic Epilepsy After Mild and Moderate Traumatic Brain Injury: A Narrative Review and Development of a Clinical Decision Tool

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Study Overview This review article examines the complex relationship between post-traumatic epilepsy (PTE) and mild …

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Traumatic brain injury
The role of genetic and epigenetic factors in sports-related muscle, bone, and brain injuries

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Genetic Influences on Injury Susceptibility The susceptibility to injuries among athletes is significantly influenced by …

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Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report
Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of…
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia
Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers…
Using Genetics to Shed Light on the Scientific Gray Zone of Functional Seizures
Genetic Factors in Functional Seizures Recent studies have begun to uncover the genetic underpinnings that…
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies
Study Overview This comprehensive review focuses on the advances in the management of acute migraine…
Knee Biomechanics in Individuals With a Recent Concussion During Jump-Landing Tasks
Background and Rationale The relationship between concussions and subsequent physical performance, particularly in biomechanical tasks,…

Transcranial Direct Current Stimulation in Older Adolescent with Chronic Mild Traumatic Brain Injury: A Case Study of Clinical and Functional Connectivity
This is the first case study, to our knowledge, to document pre- and post-tDCS resting-state functional MRI changes between the dorsolateral prefrontal cortex (DLPFC) and brainstem in an adolescent with chronic post-concussive symptoms following multiple mild traumatic brain injuries (mTBIs). By demonstrating that cortico-brainstem connectivity can be modulated through noninvasive neuromodulation, the novel findings of […]
On-pitch concussion management: a view of healthcare professionals in elite football
CONCLUSIONS: Based on the current findings, research should focus on developing multimodal testing batteries to detect concussion on-pitch, while football should consider implementing video analysis at all levels and temporary concussion substitutes.
MRI investigation of orientation-dependent changes in microstructure and function in a mouse model of mild traumatic brain injury
While neuroimaging studies have revealed notable white matter damage following mild traumatic brain injury (mTBI), the specific tracts and brain regions affected vary widely across studies. Here, we explored whether the spatial orientation of white matter tracts influences susceptibility to repeated mTBI, predicting that tracts oriented orthogonal to the axis of rotation of the head […]
Impulse Dyscontrol Symptoms Are Related to Amyloid Beta in Patients With Subjective Cognitive Decline and Mild Cognitive Impairment
CONCLUSION: The study identified a significant correlation between domain C of the MBI-C and CSF beta-amyloid peptide analysing Brazilian patients with SCD and MCI. The results reinforce the hypothesis of the relationship between impulsivity symptoms and amyloid pathology. Further studies involving the correlations between MBI and neuropsychiatric symptoms with AD CSF biomarkers are necessary.
Female, woman and/or girl Athlete Injury pRevention (FAIR) practical recommendations: International Olympic Committee (IOC) consensus meeting held in Lausanne, Switzerland, 2025
Female, woman and/or girl athletes' sport participation rates are rising and associated with high injury rates and burden. Using best-practice consensus methodology, we developed recommendations to guide injury prevention for female/woman/girl athletes. The Female/woman/girl Athlete Injury pRevention (FAIR) International Olympic Committee Consensus meeting was held from 31 March to 2 April 2025 (Lausanne, Switzerland).The FAIR […]