genetic predisposition

The association between APOE 𝜀4 carrierships and the detection of amyloid positivity using an Alzheimer’s disease proteomic blood test in asymptomatic Down syndrome

Study Overview This study investigates the relationship between the presence of the APOE 𝜀4 allele and the identification of amyloid

The association between APOE 𝜀4 carrierships and the detection of amyloid positivity using an Alzheimer’s disease proteomic blood test in asymptomatic Down syndrome Read Post »

Mechanisms underlying DEHP/MEHP-induced toxicity in multiple sclerosis: An integrated analysis combining network toxicology, bioinformatics, and in vivo experimental validation

Study Overview The investigation into the effects of DEHP (di(2-ethylhexyl) phthalate) and its metabolite MEHP (mono(2-ethylhexyl) phthalate) on multiple sclerosis

Mechanisms underlying DEHP/MEHP-induced toxicity in multiple sclerosis: An integrated analysis combining network toxicology, bioinformatics, and in vivo experimental validation Read Post »

Myelin Oligodendrocyte Glycoprotein (MOG) Antibodies in the Cerebrospinal Fluid of Pediatric Patients With MOG Antibody-Associated Disease: Insights From an Asian Multicenter Cohort

Study Overview In recent years, the understanding of autoimmune conditions affecting the central nervous system has advanced, highlighting the role

Myelin Oligodendrocyte Glycoprotein (MOG) Antibodies in the Cerebrospinal Fluid of Pediatric Patients With MOG Antibody-Associated Disease: Insights From an Asian Multicenter Cohort Read Post »

Causal effects of Epstein-Barr virus antibodies on autoimmune neuroinflammatory diseases: A generalised summary data-based Mendelian randomisation study

Study Overview The research investigates the complicated relationship between Epstein-Barr virus (EBV) antibodies and various autoimmune neuroinflammatory disorders. Autoimmune diseases,

Causal effects of Epstein-Barr virus antibodies on autoimmune neuroinflammatory diseases: A generalised summary data-based Mendelian randomisation study Read Post »

Updates on the Acute and Maintenance Management of Optic Neuritis Including Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, and Myelin Oligodendrocyte Glycoprotein Antibody Disease

Pathophysiology of Optic Neuritis Optic neuritis primarily stems from the inflammatory demyelination of the optic nerve, a vital structure responsible

Updates on the Acute and Maintenance Management of Optic Neuritis Including Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, and Myelin Oligodendrocyte Glycoprotein Antibody Disease Read Post »

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