Tag:

genomics

Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Design and Population The study utilized a robust multisite, multiancestry design, involving a comprehensive …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Assessment Techniques The evaluation of individuals experiencing posttraumatic headache (PTH) is crucial for determining the …

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Traumatic brain injury
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Overview of Posttraumatic Headache Posttraumatic headache (PTH) is a prevalent and often debilitating disorder that …

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Traumatic brain injury
The role of genetic and epigenetic factors in sports-related muscle, bone, and brain injuries

by myneuronews October 24, 2025

by myneuronews October 24, 2025

Genetic Influences on Injury Susceptibility The susceptibility to injuries among athletes is significantly influenced by …

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Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers in Epilepsy Recent research has increasingly focused on serum biomarkers as valuable tools …

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Functional neurological disorders
Serum biomarkers in epilepsy: More than meets the eye

by myneuronews October 10, 2025

by myneuronews October 10, 2025

Serum Biomarkers Overview Serum biomarkers have emerged as a critical aspect of understanding and diagnosing …

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Traumatic brain injury
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice

by myneuronews October 9, 2025

by myneuronews October 9, 2025

Study Overview This study investigates the effects of exercise on molecular changes following a mild …

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Bioequivalence of Two Perampanel Oral Suspension Formulations in Healthy Subjects: A Randomized Crossover Study
Study Overview The investigation focused on comparing the bioequivalence of two formulations of perampanel oral…
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits…
Functional Neurological Disorder, Sleep, and Dreaming: A Large Online Questionnaire-Based Study
Background on Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a range of neurological symptoms…
Treatments for Functional Neurological Disorder: A Practical Guide for Program Development
Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) presents a unique challenge in both…
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
Study Overview The investigation focused on addressing the often-overlooked cognitive challenges faced by individuals who…

Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review
Very few studies exist examining the effects of mild traumatic brain injury (mTBI) in patients with obesity, which is notable given that mTBI represents ~80% of all recorded TBIs. Given that approximately 40% of US adults have an obese body mass index (with predictions that this proportion will continue to increase), it would be prudent […]
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
Traumatic brain injuries (TBIs) are a global source of hospitalization, long-term disability, and death. However, age, sex, and other demographics differ widely among patients and the variable characteristics of TBIs further obscure injury outcomes. Here, we used Drosophila melanogaster to assess the effects of mild, repeated TBI (multi-day, MD) compared to single, severe TBI (single-day, […]
C-FLAIR: Fluid-attenuated Inversion Recovery with Controlled Artifact Suppression in Brain MRI
Background The T2-weighted fluid-attenuated inversion recovery (FLAIR) sequence is part of the routine brain MRI protocol. In regions with strong inhomogeneities in the static magnetic (B(0)) field and/or the radiofrequency (RF) field, inadequate magnetization inversion results in artifacts that may mimic or obscure pathologic features. Purpose To reduce artifacts on FLAIR images by using an […]
Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats
Although previous studies have demonstrated the effects of concussions do not accumulate as the time interval between injuries increases, little is known about the relationship between this interval and the effects of repetitive concussions. The objective of this study is to explore the relationship between the time interval and changes in behavior and histology following […]
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
CONCLUSION/IMPLICATIONS: Through a multistep process that incorporated stakeholder input and a review of the empirical literature, we developed an evidence-informed intervention that fills a gap in current care for cognitive PPCSs. Future studies are needed to evaluate the efficacy of this intervention for individuals with chronic cognitive difficulties after mTBI. (PsycInfo Database Record (c) 2025 […]