Tag:

genomics

Dementia
Consideration of sex as a biological variable over the history of the 5xFAD Alzheimer’s Disease mouse model

by myneuronews December 17, 2025

by myneuronews December 17, 2025

Biological Considerations When investigating Alzheimer’s disease through animal models, particularly the 5xFAD mouse model, it …

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Functional neurological disorders
An Integrative Approach to Functional Neurological Disorder

by myneuronews December 8, 2025

by myneuronews December 8, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex interplay of neurological symptoms …

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Traumatic brain injury
Neurobehavioral disorders: efficacy of post-hospital specialty programs

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Program Outcomes The effectiveness of post-hospital specialty programs aimed at treating neurobehavioral disorders is evaluated …

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Traumatic brain injury
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health …

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Functional neurological disorders
Motor stereotypies, Dhat syndrome, and gaming disorder: A masquerading presentation of Wilson’s disease

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Clinical Manifestations of Wilson’s Disease Wilson’s disease is a genetic disorder that leads to excessive …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Summary The study conducts a comprehensive meta-analysis of genome-wide association studies (GWAS) focused on …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Design and Population The study utilized a robust multisite, multiancestry design, involving a comprehensive …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
A Comprehensive Approach to the Assessment and Management of Posttraumatic Headache

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Assessment Techniques The evaluation of individuals experiencing posttraumatic headache (PTH) is crucial for determining the …

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Occult spinal CSF leak: to patch or not to patch-a case-based update
Occult Spinal CSF Leak Mechanisms Occult spinal cerebrospinal fluid (CSF) leaks occur when there is…
Active music therapy reduces depressive symptoms and enhances sleep and daily-life autonomy in older adults
Study Overview The research investigated the impact of active music therapy on older adults, particularly…
Functional movement disorder mimicking oromandibular dyskinesia
Clinical Presentation and Symptoms Patients with functional movement disorder (FMD) that mimics oromandibular dyskinesia often…
Soft-voting classifier for outcome prediction in traumatic brain injury patients with clear consciousness: model development and error pattern analysis
Study Overview This study addresses a significant gap in the field of traumatic brain injury…
Chronic dynamic behavioral changes and upregulation of glutamatergic signaling proteins following traumatic brain injury in females
Study Overview Traumatic brain injury (TBI) presents a significant challenge in contemporary neuroscience, particularly concerning…

Higher Cardiovascular Risk Factor Burden Associated With Cumulative Concussion History and Age-Related Differences
CONCLUSION: Given higher rates of diagnoses at earlier ages, findings support cardiovascular health as representing one pathway by which recurrent concussion may lead to adverse long-term outcomes in former contact sport athletes. A clinical preventative approach including early screening and management of CRF in those with greater history of concussion should be considered.
Head Injuries in the Wild West: A Comparison of Head Injuries in English and Western Collegiate Equestrian Athletes
CONCLUSIONS: All equestrians have a high incidence of head injuries; however, Western riders reported a higher number of falls in the previous year than their English counterparts. In addition, Western riders reported less consistent helmet use when compared with their English counterparts, who are more likely to always wear helmets when riding. This study highlights […]
Sleep disturbance after pediatric and adolescent concussion
INTRODUCTION: Sleep disturbances following concussion are common. The goal of this study was to describe subjective reports of sleep disturbances for pediatric and adolescent patients, whether they predict prolonged recovery or moderate the relationship between comorbidities, symptom burden, and recovery.
National Football League (NFL) "Dynamic Kickoff" Rule Change: A Comparative Analysis of Concussion and Musculoskeletal Injury Incidence
CONCLUSION: Our study showed that after the 2024 NFL kickoff rules were implemented, there was a significant increase in overall, lower extremity, and upper extremity injuries compared with the previous 2 seasons, as measured by the number of kickoffs and returns per year. The overall effect of the 2024 NFL kickoff rules on the incidence […]
Neuroprotective Serotonin 2A Receptor Peptide Significantly Reduced Hippocampal Inflammation in Rats Exposed to Mild Traumatic Brain Injury
CONCLUSION: These results suggest that the neuroprotective effects of SN..8 peptide may be due in part to its ability to substantially suppress subacute inflammation in the ventral hippocampus.