Tag:

genomics

Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion characteristics in dyskinetic cerebral palsy Dyskinetic cerebral palsy (CP) is a complex condition characterized …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Movement Disorders
Metabolic abnormalities of the cortico‑striato‑thalamo‑cortical circuit of rats with tic disorder

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Metabolic Alterations in Tic Disorders Research into tic disorders has revealed significant metabolic changes that …

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Functional neurological disorders
Environmental Levels of Bis(2-ethylhexyl)-tetrabromophthalate (TBPH) Cause Thyroid Toxicity and Early Carcinogenic Signals in Juvenile Fish

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Environmental Impact of TBPH Bis(2-ethylhexyl)-tetrabromophthalate (TBPH) is a brominated flame retardant commonly used in various …

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Functional neurological disorders
Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Advancements in Biomarker Identification Recent developments in the field of Alzheimer’s disease diagnostics have centered …

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Functional neurological disorders
Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Understanding Neurodevelopmental Copy Number Variants Neurodevelopmental copy number variants (CNVs) are structural alterations in the …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Functional neurological disorders
From Tiny Exons to Big Insights: The Expanding Field of Microexons

by myneuronews May 20, 2025

by myneuronews May 20, 2025

The Role of Microexons in Gene Regulation Microexons, which are typically smaller than 50 nucleotides, …

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Functional neurological disorders
Multiple system biology approaches reveals the role of the hsa-miR-21 in increasing risk of neurological disorders in patients suffering from hypertension

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Role of hsa-miR-21 in Neurological Disorders The study investigates the important role of hsa-miR-21, a …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Performance and Physiological Response to the Buffalo Concussion Treadmill Test Can Identify Autonomic Dysfunction in the General Adult Population With Mild Traumatic Brain Injury: A Prospective Observational Study
CONCLUSION: This study demonstrates that the inability to exercise to a threshold HR of 90% of an individual's age-predicted maximum HR is a better indicator of autonomic dysfunction. HRR may be prolonged in those with a mild TBI, but caution should be taken if attributing this to physiological dysfunction as the predominant factor appears to […]
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods
Military service members (SMs) and veterans who have sustained one or more concussions during their service have significantly higher rates of persistent depressive symptoms and suicidality compared to non-injured peers. Despite over 500,000 SMs who have sustained concussions, there are currently no Level I evidence-based treatments for improving depressive symptoms associated with concussion. Accelerated intermittent […]
Dietary Intake of n-3 Polyunsaturated Fatty Acids Prior to a Mild Traumatic Brain Injury Demonstrates a Dose-Response Effect for Neuroprotective Benefits in Male C57BL/6 Mice
CONCLUSIONS: Overall, these results show that dietary n-3 PUFA confer neuroprotective benefits in mice resulting in significantly improved functional outcomes. This work is relevant to clinical practitioners, athletes, and the general population who aim to support their neurological health through dietary or supplementary n-3 PUFA.
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared to Orthopedic Injury
CONCLUSIONS AND RELEVANCE: BDNF DNAm appears to differ in children with TBI vs OI, particularly in the acute period. BDNF DNAm differences may reflect early biological responses that are specific to TBI.
The Experience of Return to Work Among People with Persistent Symptoms Following a Concussion: An Interview Study
CONCLUSION: Recognition in daily life seem to play a key role in the RTW process for individuals with persistent symptoms following a concussion. They struggle to balance their limitations to match their desire to both work and family life. The support they received was often random and they felt lonely. The findings reflect the participant's […]