Tag:

genomics

Functional neurological disorders
Environmental Levels of Bis(2-ethylhexyl)-tetrabromophthalate (TBPH) Cause Thyroid Toxicity and Early Carcinogenic Signals in Juvenile Fish

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Environmental Impact of TBPH Bis(2-ethylhexyl)-tetrabromophthalate (TBPH) is a brominated flame retardant commonly used in various …

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Functional neurological disorders
Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Advancements in Biomarker Identification Recent developments in the field of Alzheimer’s disease diagnostics have centered …

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Functional neurological disorders
Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Understanding Neurodevelopmental Copy Number Variants Neurodevelopmental copy number variants (CNVs) are structural alterations in the …

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Functional neurological disorders
From Tiny Exons to Big Insights: The Expanding Field of Microexons

by myneuronews May 20, 2025

by myneuronews May 20, 2025

The Role of Microexons in Gene Regulation Microexons, which are typically smaller than 50 nucleotides, …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Functional neurological disorders
Multiple system biology approaches reveals the role of the hsa-miR-21 in increasing risk of neurological disorders in patients suffering from hypertension

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Role of hsa-miR-21 in Neurological Disorders The study investigates the important role of hsa-miR-21, a …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Factors Influencing Parkinson’s Disease Parkinson’s Disease (PD) is a progressive neurodegenerative disorder primarily characterized …

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Headaches
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Background on Migraine and Genomics Migraine is a prevalent and often debilitating neurological condition characterized …

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Functional neurological disorders
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Cholinergic Pathways in Parkinson’s Disease In the context of Parkinson’s disease, understanding the role of …

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Comparing Single-Site Fractures with Multisite Injuries in Pediatric Skiers and Snowboarders
Introduction-The purpose of this study was to evaluate pediatric skiing and snowboarding fracture injuries at a large ski resort, comparing injury patterns in those who sustained fracture injuries at a single site against those with injuries in multiple sites. Given the more serious nature of multisite injuries, this information may give healthcare providers insight into […]
Impacts of traumatic brain injury severity and sex on sleep architecture, duration, and fragmentation
Traumatic brain injury (TBI) is frequently associated with acute and chronic disturbances in sleep architecture. However, the extent to which injury severity and biological sex influence post-traumatic sleep patterns remains underexplored in preclinical models. Here, we used a validated, noninvasive piezoelectric monitoring system to assess sleep in male and female mice following sham (n = […]
Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired <em>APOE</em> ε4 carriers
CONCLUSION: Successful demonstration of a scalable, home-based, high-intensity aerobic exercise intervention in altering the trajectory of AD pathophysiology and its effects on cognitive functioning will transform AD treatment, improve patient outcomes and quality of life, and reduce healthcare costs.
Volumetric and Diffusion Tensor Imaging Abnormalities Are Associated With Behavioral Changes Post-Concussion in a Youth Pig Model of Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) caused by sports-related incidents in children and youth often leads to prolonged cognitive impairments but remains difficult to diagnose. In order to identify clinically relevant imaging and behavioral biomarkers associated concussion, a closed-head mTBI was induced in adolescent pigs. Twelve (n = 4 male and n = 8 female), 16-week […]
Virtual reality-based eye tracking throughout typical concussion recovery
Objective: The purpose of this study was to determine the effects of concussion on visual and oculomotor function using a virtual reality-based eye tracking system throughout recovery. Design: A prospective, longitudinal cohort design assessed at the subacute, return-to-activity, and 6-month timepoints was used. Methods: Recently concussed (n = 21; age = 30 ± 14) and […]