Tag:

GFAP

Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

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Traumatic brain injury
Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The evaluation centered on the efficacy and reliability of the TBI Assay within …

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Traumatic brain injury
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients

by myneuronews October 8, 2025

by myneuronews October 8, 2025

Study Overview This study examined the efficacy of three biomarkers—GFAP (Glial Fibrillary Acidic Protein), UCH-L1 …

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Traumatic brain injury
IL6 in Combination with Either NfL, NTproBNP, or GFAP to Safely Discharge Children with Mild Traumatic Brain Injury

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Background and Rationale The investigation into the role of interleukin-6 (IL-6) in conjunction with biomarkers …

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Traumatic brain injury
Blood Biomarkers as Optimization Tools for Computed Tomography in Mild Traumatic Brain Injury Management in Emergency Departments: A Systematic Review

by myneuronews August 27, 2025

by myneuronews August 27, 2025

Blood Biomarkers and Their Role Blood biomarkers are measurable substances in the blood that can …

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Traumatic brain injury
Sensitivity of Diffusion Tensor Imaging for Assessing Injury Severity in a Rat Model of Isolated Diffuse Axonal Injury: Comparison with Histology and Neurological Assessment

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview This investigation centers on the evaluation of diffusion tensor imaging (DTI) as a …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes in Glial Scarring After a traumatic brain injury (TBI), the central nervous system …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes During Glial Scar Formation After a traumatic brain injury (TBI), the brain undergoes …

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Traumatic brain injury
Letter: Mild Traumatic Brain Injury in Older Adults: Recovery Course and Insights on Early Predictors of Outcome

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Recovery Patterns in Older Adults The recovery patterns following mild traumatic brain injury (mTBI) in …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Measurement of perceived social support among people with dementia: a validation of the Indonesian version of the personal resource questionnaire-2000 (PRQ2000-INA)
Study Overview The study aimed to assess the validity of the Indonesian version of the…
Phenotyping Functional Gait Disorder: An Exploratory Analysis of Existing Frameworks
Phenotyping Functional Gait Disorder Functional Gait Disorder (FGD) is increasingly recognized as a complex presentation…
Diagnosis and treatment of functional visual disorder
Understanding Functional Visual Disorder Functional Visual Disorder (FVD) is a complex condition where individuals experience…
Risk of suicidal behaviors following sport-related and non-sport-related concussion: a systematic review and meta-analysis
Risk Assessment In exploring the risk of suicidal behaviors following concussions, it is critical to…
Kerala Brain Injury Questionnaire: Feasibility, Reliability, and Validation Study
Study Overview The Kerala Brain Injury Questionnaire (KBIQ) study aimed to assess the feasibility, reliability,…

Bidirectional Interplay Between Traumatic Brain Injury and Cardiovascular Dysfunction in Athletes
Sports-associated traumatic brain injury is emerging as an under-recognized driver of acute and chronic cardiovascular diseases. Larger population-based studies show that individuals with moderate-to-severe traumatic brain injury experience up to a two-fold excess risk of incident hypertension, coronary artery disease, myocardial infarction, and stroke that persists for at least a decade. Among former professional American-style […]
Objective Markers for Diagnosing Concussions: Beyond Blood Biomarkers and the Role of Real-Time Diagnostic Tools
Concussions, classified as a type of mild traumatic brain injury (mTBI), are frequently underdiagnosed due to the subjective nature of symptoms and limitations in existing diagnostic methodologies. Current clinical evaluations, including tools such as the Sport Concussion Assessment Tool 5 (SCAT5), Balance Error Scoring System (BESS), and Vestibular Ocular Motor Screening (VOMS), demonstrate high sensitivity […]
Microglia depletion improves hippocampal circuit function after mild traumatic brain injury in male mice
Traumatic brain injury (TBI) affects over 69 million people every year, and mild traumatic brain injury (mTBI) accounts for 70-90 % of cases. TBI has two components: i) primary injury - direct damage to the tissue from the mechanical impact and ii) secondary injury - additional or extended damage to the tissue from the ensuing […]
The Interaction of Sleep and Mood During Recovery from Mild Traumatic Brain Injury
Insomnia and depression are common co-morbidities associated with mild traumatic brain injury (mTBI). Data from Transforming Research and Clinical Knowledge in TBI, a longitudinal cohort study of TBI and orthopedic controls (OTC), were used to examine insomnia trajectories and the temporal relationship between insomnia and depressive symptoms during recovery. mTBI (n = 1,557) and OTC […]
Characteristics, Context and Injury Mechanism of Traumatic Brain Injuries at Laquintinie Hospital in Douala: An In-Depth Analysis Over 5 Years
CONCLUSION: Preventive measures targeting road safety, alcohol consumption and vehicle overloading are essential to reduce the prevalence of TBIs in Cameroon.