Tag:

GFAP

Traumatic brain injury
Brain Ischemia Across Injury Severity in Traumatic Brain Injury and an Association with Abusive Head Trauma

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Pathophysiology of Brain Ischemia Brain ischemia occurs when there is a deficiency of blood supply …

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Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

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Traumatic brain injury
Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The evaluation centered on the efficacy and reliability of the TBI Assay within …

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Traumatic brain injury
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients

by myneuronews October 8, 2025

by myneuronews October 8, 2025

Study Overview This study examined the efficacy of three biomarkers—GFAP (Glial Fibrillary Acidic Protein), UCH-L1 …

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Traumatic brain injury
IL6 in Combination with Either NfL, NTproBNP, or GFAP to Safely Discharge Children with Mild Traumatic Brain Injury

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Background and Rationale The investigation into the role of interleukin-6 (IL-6) in conjunction with biomarkers …

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Traumatic brain injury
Blood Biomarkers as Optimization Tools for Computed Tomography in Mild Traumatic Brain Injury Management in Emergency Departments: A Systematic Review

by myneuronews August 27, 2025

by myneuronews August 27, 2025

Blood Biomarkers and Their Role Blood biomarkers are measurable substances in the blood that can …

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Traumatic brain injury
Sensitivity of Diffusion Tensor Imaging for Assessing Injury Severity in a Rat Model of Isolated Diffuse Axonal Injury: Comparison with Histology and Neurological Assessment

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview This investigation centers on the evaluation of diffusion tensor imaging (DTI) as a …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes in Glial Scarring After a traumatic brain injury (TBI), the central nervous system …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes During Glial Scar Formation After a traumatic brain injury (TBI), the brain undergoes …

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Traumatic brain injury
Letter: Mild Traumatic Brain Injury in Older Adults: Recovery Course and Insights on Early Predictors of Outcome

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Recovery Patterns in Older Adults The recovery patterns following mild traumatic brain injury (mTBI) in …

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An update on hypophysitis
Study Overview Recent research has focused on the complexities of hypophysitis, an inflammation of the…
Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson’s disease and Lewy Body Dementia cohorts
Study Overview This research investigates the presence and significance of expanded and interrupted repeat expansions…
Intracranial Injury Caused by Transorbital Penetrating Trauma: An E-Scooter Brake Handle as an Unusual Culprit
Study Overview In recent years, the popularity of e-scooters has surged, bringing with it a…
The Influence of Aerobic Exercise Therapy on Patient-Reported Outcome Measures Following Concussion: A Scoping Review
Study Overview The rising recognition of concussion as a significant public health concern has sparked…
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health…

Intracranial Injury Caused by Transorbital Penetrating Trauma: An E-Scooter Brake Handle as an Unusual Culprit
Transorbital penetrating intracranial injuries are a rare but life-threatening subset of penetrating head traumas. While isolated cases caused by bicycle brake handles have been reported, often with fatal outcomes, this is the first documented case of such an injury caused by an electric scooter (e-scooter) brake handle. The objective is to present the unique management […]
The Influence of Aerobic Exercise Therapy on Patient-Reported Outcome Measures Following Concussion: A Scoping Review
Background/Objectives: The purpose of this scoping review was to identify the effects of exercise therapy on patient-reported outcome measure(s) (PROM(s)) after concussion, and to highlight the current knowledge gaps in the literature. Methods: A search of EMBASE, MEDLINE, SCOPUS, BIOSIS, and Cochrane Libraries was performed on 1 December 2023 (from database inception) and updated on […]
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Objectives: This in silico study sought to identify specific biomarkers for mild traumatic brain injury (mTBI) through the analysis of publicly available gene and miRNA databases, hypothesizing their influence on neuronal structure, axonal integrity, and regeneration. Methods: This study implemented a three-step process: (1) data searching for mTBI-related genes in Gene and MalaCard databases and […]
Concussion-Related Cognitive and Lipid Changes in Retired UK Rugby Players Study
Long-term effects of concussions, particularly in contact sport athletes, have been linked to changes in neuronal health. Lipid dysregulation has emerged as a potential contributor to neuronal injury and may serve as a measurable biomarker of brain pathology. This study investigated cognitive scores and serum lipid biomarkers in retired rugby players with a history of […]
Harmonisation and implementation of sports-related concussion guidelines in European youth football: the REFORM Erasmus+ project
INTRODUCTION: Sports-related concussions (SRCs) are frequently under-reported in youth sports, especially football, due to limited awareness, inconsistent reporting practices and a lack of medical personnel at the grassroots level. Concussion management protocols vary widely across regions, highlighting the need for a standardised approach. This study aims to harmonise SRC education and management practices in European […]