Tag:

Glasgow Outcome Scale

Traumatic brain injury
Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury

by myneuronews January 9, 2026

by myneuronews January 9, 2026

Study Overview The research focuses on understanding how specific proteins called cytokines and chemokines, which …

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Traumatic brain injury
Is tranexamic acid effective for all traumatic brain injury patients? a severity based systematic review and meta-analysis

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Effectiveness of Tranexamic Acid Tranexamic acid, an antifibrinolytic medication, has garnered attention for its potential …

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Traumatic brain injury
External validation of the modified Brain Injury Guidelines: an observational study

by myneuronews December 25, 2025

by myneuronews December 25, 2025

Study Overview This observational study focuses on the external validation of the modified Brain Injury …

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Traumatic brain injury
Soft-voting classifier for outcome prediction in traumatic brain injury patients with clear consciousness: model development and error pattern analysis

by myneuronews December 21, 2025

by myneuronews December 21, 2025

Study Overview This study addresses a significant gap in the field of traumatic brain injury …

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Traumatic brain injury
Traumatic brain injury outcomes and mortality predictors in Eastern India: An observational study

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Traumatic brain injury demographics The demographics of individuals experiencing traumatic brain injuries (TBIs) in Eastern …

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Headaches
Microsurgical Management of Anterior Inferior Cerebellar Artery Aneurysms: Case Series and Review of Advanced Imaging and Cranial Base Approaches

by myneuronews November 9, 2025

by myneuronews November 9, 2025

Background and Significance Aneurysms associated with the anterior inferior cerebellar artery (AICA) are relatively rare …

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Traumatic brain injury
“Talk and die” syndrome, a tragedy in traumatic brain injury: a cohort study

by myneuronews October 20, 2025

by myneuronews October 20, 2025

Understanding “Talk and Die” Syndrome “Talk and Die” syndrome is a critical phenomenon observed in …

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Traumatic brain injury
Absence from work in the 12 months following mild traumatic brain injury in Europe: a CENTER-TBI cohort study

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Study Overview This research delves into the patterns of absence from work experienced by individuals …

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Traumatic brain injury
Disparities in provision of rehabilitative services in adolescents with traumatic brain injury at level I adult versus pediatric trauma centers

by myneuronews August 21, 2025

by myneuronews August 21, 2025

Service Disparities The provision of rehabilitative services to adolescents who have experienced traumatic brain injury …

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Traumatic brain injury
Glasgow Coma Scale Score at Admission in Traumatic Brain Injury Patients: A Multicenter Observational Analysis

by myneuronews August 14, 2025

by myneuronews August 14, 2025

Study Overview This multicenter observational analysis focuses on the role of the Glasgow Coma Scale …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]