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healthcare

Functional neurological disorders
Exploring Baralle-Macken Syndrome: A Novel COPB1 Mutation in Consanguineous Pakistani Siblings

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Case Description of Baralle-Macken Syndrome Baralle-Macken Syndrome is a rare genetic condition often presented through …

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Functional neurological disorders
Functional neurological disorder: Practical management

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) represents a complex interplay between neurological and …

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Dementia
Door Decals for Wayfinding and Redirection: A Quality Improvement Project Involving the Use of Clinical Real-Time Location Systems for Evaluation of Environmental Design Changes

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Project Objectives The primary goals of this quality improvement project were centered around enhancing patient …

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Headaches
Long-term safety and tolerability of zavegepant 10-mg nasal spray with concomitant use of anti-calcitonin gene-related peptide monoclonal antibodies or other select preventive migraine medications: Results from a phase 2/3 open-label study

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Study Overview This phase 2/3 open-label study was designed to evaluate the long-term safety and …

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Traumatic brain injury
Using the Theory of Planned Behavior in Considering the Efficacy of Encountering Concussion Intervention Materials Online

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Theoretical Framework The Theory of Planned Behavior (TPB) serves as a foundational framework for understanding …

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Traumatic brain injury
Neuroimaging Characterization of Acute Traumatic Brain Injury with Focus on Frontline Clinicians: Recommendations from the 2024 National Institute of Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Imaging Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Neuroimaging Techniques in Traumatic Brain Injury Neuroimaging plays a crucial role in the assessment and …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Functional neurological disorders
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

by myneuronews May 20, 2025

by myneuronews May 20, 2025

HSD17B1 Role in Trophoblast Differentiation The study of HSD17B1 (Hydroxysteroid Dehydrogenase Type 1) highlights its …

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Functional neurological disorders
Atypical cadherin FAT2 is required for synaptic integrity and motor behaviors

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Role of fat2 in Synaptic Integrity The study of the atypical cadherin FAT2 unveils its …

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Functional neurological disorders
Functional Movement Disorder: Evolving Mechanisms, Diagnostic Precision, and Personalized Multidisciplinary Care

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Functional Movement Disorder Functional Movement Disorder (FMD) encompasses a range of abnormal movement patterns …

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Subtype shift, relapse rate and risk factors of frequent relapse in cluster headache: A multicenter, prospective, longitudinal observation
Study Overview The study focused on understanding the various types of cluster headaches, examining the…
Quercetin as a Multi-Target Natural Therapeutic in Aging-Related Diseases: Systemic Molecular and Cellular Mechanisms
Mechanisms of Action Quercetin, a flavonoid found abundantly in many fruits, vegetables, and beverages, exhibits…
Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
Understanding Suicidal Ideation Suicidal ideation refers to the thoughts or considerations of ending one’s own…
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Neurophysiological Insights The neurophysiological aspects of downhill mountain biking are critical to understanding how athletes…
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Study Overview This study investigates the morphological changes in microglia, the immune cells of the…

Exploring suicidal ideation and self-harm after moderate-severe traumatic brain injury within a transdiagnostic framework
More research is needed on suicidal ideation (SI) and self-harm (SH) following moderate-severe traumatic brain injury (TBI). Previous studies have shown limited, inconsistent associations with demographic and injury factors and relied on diagnosis-specific analyses of psychiatric factors. This cross-sectional survey included 387 individuals with moderate-severe TBI and examined correlations between SI, SH, and 35 other […]
Neurophysiology of Downhill Mountain Bike Athletes-Benchmark Assessments of Event-Related Potentials
Background: Downhill mountain biking (MTB) is a high-velocity sport where riders are potentially exposed to impacts and concussion. Rapidly obtained Event-Related Potentials (ERPs) are a promising use of portable electroencephalography for clinical assessment of concussion-related neurological impairment at the point of care. However, the baseline neuroelectric profile of this specific sporting population is not fully […]
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats
Mild traumatic brain injury (mTBI) affects over 40 million people every year. One of its features includes the activation of microglia, the resident immune cells of the brain. Microglia assume different morphological states depending on their level of activation, such as surveilling ramified and activated hypertrophic, ameboid, and rod-like microglia. These states can be distinguished […]
Evaluation of Traumatic Brain Injury Severity Using the Abbreviated Injury Scale and the Injury Severity Score: A Retrospective Study in Two Eastern European Centers
Introduction: Traumatic brain injury (TBI) is a significant global public health issue, with long-term impacts on patients. This study examines the relationship between TBI severity, as measured by the Abbreviated Injury Scale (AIS) and the Injury Severity Score (ISS) at admission, and various sociodemographic, clinical, and injury-related factors. Methods: We conducted a retrospective analysis using […]
Non-invasive vagus nerve stimulation is associated with the reduction in persistent post-concussion symptoms: an observational study
INTRODUCTION: Traumatic brain injury (TBI) remains a major public health challenge, with mild TBI (mTBI) frequently resulting in persistent cognitive, affective, and somatic symptoms. Non-invasive vagus nerve stimulation (nVNS) has demonstrated potential in reducing neuroinflammation and promoting recovery in preclinical TBI models. This retrospective, observational study assessed the impact of adjunctive nVNS on postconcussive symptoms […]