Tag:

ImPACT

Headaches
Long-term safety and tolerability of zavegepant 10-mg nasal spray with concomitant use of anti-calcitonin gene-related peptide monoclonal antibodies or other select preventive migraine medications: Results from a phase 2/3 open-label study

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Study Overview This phase 2/3 open-label study was designed to evaluate the long-term safety and …

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Traumatic brain injury
Using the Theory of Planned Behavior in Considering the Efficacy of Encountering Concussion Intervention Materials Online

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Theoretical Framework The Theory of Planned Behavior (TPB) serves as a foundational framework for understanding …

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Traumatic brain injury
Genome-wide analysis of lncRNA m6A methylation in the mouse cortex after repetitive mild traumatic brain injury

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Background on lncRNA and m6A Methylation Long non-coding RNAs (lncRNAs) are an intriguing class of …

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Traumatic brain injury
Patient-Reported Outcomes Measurement Information System (PROMIS) outcomes: Higher odds of adverse mental health when physical function is impaired

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Impact of Physical Function on Mental Health Physical function is a critical component of overall …

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Traumatic brain injury
The Relationship Between Sex, Fatigue, and Post-Concussion Symptoms Differs Between Those With Mild Traumatic Brain Injury Versus Trauma Control and Healthy Control Participants

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Study Overview In recent years, the complex interplay between sex, fatigue, and post-concussion symptoms has …

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Traumatic brain injury
Somatic Symptom Disorder After Mild Traumatic Brain Injury

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Somatic Symptom Disorder Somatic Symptom Disorder (SSD) is characterized by the presence of physical …

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Dementia
The Impact of Dietary Intake and Nutritional Status on the Oral Health of Older Adults Living in Care Homes: A Scoping Review

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Dietary Impacts The relationship between dietary intake and oral health in older adults, particularly …

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Headaches
Raising the bar in migraine prevention: Toward freedom and optimal control

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Current Approaches to Migraine Prevention Migraine prevention encompasses a variety of methodologies aimed at reducing …

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Traumatic brain injury
Imaging a concussion and the ensuing immune response at the blood-brain barrier

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding the Blood-Brain Barrier The blood-brain barrier (BBB) is a highly selective permeability barrier that …

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Traumatic brain injury
Optimal Diagnostic Strategies for Concussion-Related Vision Disorders: A Review

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Concussion-Related Vision Disorders Concussion-related vision disorders encompass a range of visual symptoms that can …

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Peripheral Nerve Stimulation Is Effective in the Management of Trigeminal Pain: A Systematic Review and meta-analysis
Study Overview The systematic review and meta-analysis addressed the effectiveness of peripheral nerve stimulation (PNS)…
Evaluation of Suspected Dementia
Understanding Dementia Evaluation Dementia evaluation is a complex process designed to identify cognitive decline that…
Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits
Study Overview This research investigates the roles of specific biomarkers—ubiquitin C-terminal hydrolase-L1 (UCH-L1), glial fibrillary…
Correlation of Optic Nerve Sheath Diameter With Severity and Outcome in Head Injury: Ultrasonographic and CT Evaluation
Study Overview The research focused on evaluating the relationship between the diameter of the optic…
Admission blood glucose and neutrophil-to-lymphocyte ratio for differentiating CT-positive from CT-negative mild traumatic brain injury
Study Overview This research investigates the potential of admission blood glucose levels and the neutrophil-to-lymphocyte…

Study of ubiquitin C-terminal hydrolase-L1, glial fibrillary acidic protein, and interleukin-6 levels in an experimental head trauma model in rabbits
CONCLUSION: Serum UCH-L1 differentiated moderate and severe trauma from controls in a rabbit model, whereas CSF GFAP and IL-6 levels reflected severe injury. Validation in larger preclinical and clinical studies is warranted.
Correlation of Optic Nerve Sheath Diameter With Severity and Outcome in Head Injury: Ultrasonographic and CT Evaluation
Objective This study aimed to determine the extent to which ultrasonographic and computed tomographic (CT) measurements of the optic nerve sheath diameter (ONSD) correlate with the prognosis and severity of traumatic brain injury (TBI). Methodology A prospective cohort study was conducted among 200 adult patients admitted to a Level 1 trauma center over one year. […]
Admission blood glucose and neutrophil-to-lymphocyte ratio for differentiating CT-positive from CT-negative mild traumatic brain injury
This study aimed to assess the diagnostic utility of routine laboratory biomarkers in adults with mTBI. We conducted a prospective study of patients who were admitted to the neurosurgical department with mTBI, had admission laboratory data available, and a brain CT scan was performed. The cohort included 101 patients (mean age: 59 ± 23.14 years). […]
Bidirectional Relationship Between Mental Health and Sports Injury in Adolescents: A Systematic Review and Meta-analysis
CONCLUSIONS: We found evidence for a bidirectional relationship between sports injuries and mental health in adolescent athletes. Further research is needed to elucidate the mechanisms underlying this relationship. Early interventions focusing on supporting mental health after sports injury, and addressing pre-existing mental health issues to reduce the risk of subsequent injury, should be tailored towards […]
Does Timing of Concussion in Season Affect Incidence and Recovery in Division I Collegiate Football Players? A CARE Consortium Study
CONCLUSIONS: In a multi-institution cohort of collegiate football players, preseason resulted in the highest incidence of concussions, while early and late-season concussions had significantly longer time to SR compared to preseason. These temporal patterns suggest that contextual factors may influence concussion outcomes and warrant mechanistic investigation to inform future management strategies.