Tag:

ImPACT

Traumatic brain injury
Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Early Pupil Abnormality and Its Significance Pupil abnormalities, such as asymmetry or non-reactivity to light, …

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Traumatic brain injury
Effects of Subanesthetic Intravenous Ketamine Infusion on Stress Hormones and Synaptic Density in Rats with Mild Closed-Head Injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Effects of Ketamine on Stress Hormones Research on the impact of ketamine, particularly in its …

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Traumatic brain injury
Single-Quantum Sodium MRI at 3T for the Separation of Mono- and Bi-T2 Sodium Signals

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Study Overview The study investigates an innovative approach to magnetic resonance imaging (MRI) aimed at …

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Dementia
FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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Traumatic brain injury
Retinal manifestations of traumatic brain injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Retinal Changes Associated with Traumatic Brain Injury Traumatic brain injury (TBI) can lead to various …

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Traumatic brain injury
Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Study Overview The research undertaken aimed to establish a reliable and straightforward model of mild …

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Traumatic brain injury
Equestrian STAR: Development of an Experimental Methodology for Assessing the Biomechanical Performance of Equestrian Helmets

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Study overview The research aimed to establish a novel methodology for evaluating the biomechanical performance …

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Dementia
Resistance and resilience to Alzheimer’s disease in Down syndrome

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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Traumatic brain injury
Concussions Are Associated With Increases in Blood Pressure and Cardiovascular Risk in American-Style Football Athletes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Impact of Concussions on Cardiovascular Health Recent research has highlighted a concerning link between concussions …

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Traumatic brain injury
Computed Tomography Findings of Children Under 3 Years of Age with Mild Traumatic Brain Injury (TBI) and No Neurological Focal Signs

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Computed Tomography Characteristics Computed tomography (CT) plays a crucial role in evaluating pediatric patients with …

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Extracellular Vesicle-Derived microRNAs as Fluid Biomarkers in Neurodegenerative Diseases: A Systematic Review
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. Extracellular vesicles (EVs) have emerged as promising biomarkers for neurodegeneration, owing to their accessibility in bodily fluids and dynamic molecular cargo, including microRNAs (miRNAs). The last decade has seen accumulating evidence for miRNA dysregulation in […]
P75NTR blockading inhibits Trem2+ M1 phenotype microglia activation and myelin damage following mild traumatic brain injury
The pathological basis underlying mild traumatic brain injury (mTBI)-induced long-term cognitive impairment is not fully understood. It is supposed that mTBI induces residential microglia activation rather than peripheral leukocyte infiltration to promote neuroinflammation, thus triggering myelin damage as well as cognitive impairment. The transformation of microglia towards a pro-inflammatory (M1 type) or anti-inflammatory (M2 type) […]
Biofluid-based predictors of post-concussion symptoms: a narrative review of mild traumatic brain injury biomarkers
Mild traumatic brain injury can disrupt brain function and is associated with high morbidity and healthcare utilization. While many individuals recover from mild traumatic brain injury, a significant proportion experience long-term sequelae, collectively known as post-concussion syndrome. Symptoms of post-concussion syndrome include headache, dizziness, insomnia, cognitive processing difficulties and mental health disturbances. The disease burden […]
Comparison of Six Data Cleaning Methods for Determining Repetitive Head Impact Exposure in Youth Tackle Football
CONCLUSIONS: These findings highlight the impact of data cleaning on HAE quantification in youth tackle football. Although video verification remains best practice, it is resource intensive. Time-windowed, algorithm-classified data may serve as an efficient proxy in similar cohorts, though researchers should recognize its limitations. Findings support the need for standardized data cleaning methods and transparent […]
Effect of Dose of Targeted Rehabilitation Exercises for Vestibular (T-REV) Impairments following mTBI on Dizziness Handicap: A Randomized Clinical Trial
BACKGROUND AND PURPOSE: To evaluate the effect of intensity and frequency of vestibular rehabilitation exercises over time on dizziness handicap and secondary outcomes in adults with vestibular impairments following mild traumatic brain injuries (mTBI).