Tag:

ImPACT

Functional neurological disorders
Will adaptive deep brain stimulation for Parkinson’s disease become a real option soon? A Delphi consensus study

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Adaptive Deep Brain Stimulation Approaches Adaptive deep brain stimulation (aDBS) represents a significant evolution in …

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Traumatic brain injury
An 18-Year Study of Changes in Neurocognitive Function and Associations with Repetitive Head Trauma among Former Collegiate American Football Players: A Case Series

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Study Overview This comprehensive investigation delves into the long-term effects of repetitive head trauma on …

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Traumatic brain injury
Dietary supplementation roles in concussion management: A systematic review

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Supplementation Strategies in Concussion Care Various nutritional strategies have been proposed as adjuncts to traditional …

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Traumatic brain injury
An 18-Year Study of Changes in Neurocognitive Function and Associations with Repetitive Head Trauma among Former Collegiate American Football Players: A Case Series

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Background and Rationale The interplay between repetitive head trauma and long-term neurocognitive health has become …

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Stroke
Exosome-powered neuropharmaceutics: unlocking the blood-brain barrier for next-gen therapies

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Exosome Technology in Neuropharmaceutics Exosomes represent a groundbreaking advancement in the field of neuropharmaceutics, offering …

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Functional neurological disorders
Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Clinical Efficacy of Thalamotomy The use of bilateral focused ultrasound thalamotomy (FUS) represents a significant …

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Functional neurological disorders
Reduced microstructural white matter integrity is associated with the severity of physical symptoms in functional neurological disorder

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Microstructural Changes in White Matter Research indicates that the architecture of brain white matter plays …

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Functional neurological disorders
Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Clinical Effectiveness of Thalamotomy Bilateral focused ultrasound thalamotomy (FUS thalamotomy) has emerged as a promising …

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Dementia
Grey literature scoping review: a synthesis of the application of participatory methodologies in underrepresented groups at an elevated risk of dementia

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Context of Participatory Methodologies Participatory methodologies represent an innovative approach to research, especially in healthcare …

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Movement Disorders
Exploring the association between serotonin transporter promoter region methylation levels and depressive symptoms: a systematic review and multi-level meta-analysis

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Background and Rationale The relationship between biological factors, particularly genetic and epigenetic influences, and psychological …

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The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)
Blast-induced mild traumatic brain injury (mTBI) occurs when shock waves travel through blood vessels and cerebrospinal fluid, leading to cerebral demyelination, which results in cognitive impairments and neuropsychiatric issues that impact quality of life. This study aims to evaluate myelin changes in white matter in mice with mTBI induced by an open-field low-intensity blast (LIB) […]