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ImPACT

Traumatic brain injury
Clinical manifestations and treatment of hypopituitarism due to traumatic brain injury

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Understanding Hypopituitarism Hypopituitarism is a condition characterized by the insufficient production of one or more …

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Traumatic brain injury
Sport-Related Concussions in High School Athletes: A Comprehensive Update

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Understanding Concussions in High School Sports Concussions have become a significant concern in high school …

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Traumatic brain injury
Point-of-Care Electroencephalography in Acute Neurological Care: A Narrative Review

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Application of Point-of-Care EEG Point-of-care electroencephalography (POC EEG) has emerged as a transformative tool in …

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Functional neurological disorders
Striato-cortical connectivity patterns predict clinical profiles in Huntington’s disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Striato-Cortical Connectivity in Huntington’s Disease The study systematically examined the intricacies of striato-cortical connectivity in …

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Functional neurological disorders
Gut Neuropeptide Involvement in Parkinson’s Disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Gut Neuropeptides and Their Role in Neurodegeneration Gut neuropeptides are crucial biochemical messengers that play …

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Functional neurological disorders
Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Aβ Plaque Polymorphism Overview Amyloid-beta (Aβ) plaques are characteristic features found in the brains of …

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Functional neurological disorders
Brain activation characteristics of schizophrenia and bipolar disorder-I patients during letter and category fluency tasks: An empirical study using functional near-infrared spectroscopy

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Brain Activation Patterns in Schizophrenia and Bipolar Disorder The study examined specific brain activation patterns …

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Functional neurological disorders
Dystonia: pathophysiology and the role of acupuncture in treatment

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Understanding Dystonia and Its Mechanisms Dystonia is a complex movement disorder characterized by sustained muscle …

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Functional neurological disorders
Natural sulfur compounds in mental health and neurological disorders: insights from observational and intervention studies

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Natural Sulfur Compounds and Their Role in Mental Health Natural sulfur compounds, such as garlic, …

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Traumatic brain injury
Sickness absence > 14 days following mild traumatic brain injuries from traffic accidents: a Swedish nationwide register study

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Background and Rationale Mild traumatic brain injuries (mTBIs), commonly referred to as concussions, are often …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.