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ImPACT

Traumatic brain injury
Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Understanding ADHD Post-TBI Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by persistent patterns of …

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Traumatic brain injury
Hollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Study Overview The investigation centers on the innovative application of hollow copper sulfide (CuS) nanocubes …

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Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview This research explores the phenomenon of ferroptosis, a form of regulated cell death …

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Traumatic brain injury
Access to pediatric trauma centres in Canada: a population-based retrospective cohort study

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Access Patterns Access to pediatric trauma centers in Canada is influenced by a variety of …

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Traumatic brain injury
A comprehensive review on adaptive plasticity and recovery mechanisms post-acquired brain injury

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Adaptive Plasticity Mechanisms Adaptive plasticity refers to the brain’s ability to reorganize itself in response …

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Traumatic brain injury
A study on the association of apolipoprotein E with oxidative stress markers, neurological function, and cognitive impairment following traumatic brain injury

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Association of Apolipoprotein E and Oxidative Stress Apolipoprotein E (ApoE) plays a crucial role in …

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Traumatic brain injury
Artificial Intelligence in Traumatic Brain Injury: A Systematic Review of Prognostic, Diagnostic, and Monitoring Applications

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The comprehensive review focuses on the diverse applications of artificial intelligence (AI) in …

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Traumatic brain injury
Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The research presented investigates the effectiveness of transcranial direct current stimulation (tDCS) applied …

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Dementia
Event segmentation applications in large language model enabled automated recall assessments

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Application of Event Segmentation Event segmentation is a technique that allows for the organization of …

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Headaches
The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The primary objective of this research was to investigate the role of the …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Extracranial Hemodynamic Responses to a Noxious Cold Pressor Task Differ Between Persistent Post-Traumatic Headache and Healthy Controls
Background/Objectives: Headache after a traumatic brain injury (TBI) is one of the most common post-concussive symptoms and is associated with altered pain processing and elevated disability levels. Understanding physiologic correlates of nociception in individuals with persistent post-traumatic headache (pPTH) may help identify novel treatment targets for pain-related disability. The objective of this case-control study was […]
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]