Tag:

ImPACT

Traumatic brain injury
Ferroptosis-Mediated Hippocampal Neuronal Loss Post-mTBI: Chromatin Accessibility Profiling and Single-Nucleus Transcriptomics

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Research Context The brain is a complex organ with numerous cellular interactions, and understanding these …

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Functional neurological disorders
Revisiting Psychopathological Hand as a Functional Neurological Disorder : Time to Reframe?

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Reframing Psychopathological Hand Recent discussions in the field of Functional Neurological Disorders (FND) have prompted …

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Traumatic brain injury
A Retrospective Examination of Referral Patterns to Physical Therapy After Concussion: Have We Kept Up with Current Guidelines?

by myneuronews December 14, 2025

by myneuronews December 14, 2025

Current Guidelines for Concussion Management The management of concussions has evolved significantly over the years, …

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Functional neurological disorders
Clinical ethical issues regarding functional neurological disorder: the need for patient respect and clinician education

by myneuronews December 14, 2025

by myneuronews December 14, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) is a condition where patients experience neurological …

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Functional neurological disorders
Clinical ethical issues regarding functional neurological disorder: the need for patient respect and clinician education

by myneuronews December 14, 2025

by myneuronews December 14, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) represents a complex and often misunderstood condition …

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Functional neurological disorders
Clinical ethical issues regarding functional neurological disorder: the need for patient respect and clinician education

by myneuronews December 14, 2025

by myneuronews December 14, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) represents a fascinating and complex interplay between …

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Functional neurological disorders
Clinical ethical issues regarding functional neurological disorder: the need for patient respect and clinician education

by myneuronews December 14, 2025

by myneuronews December 14, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) is a condition characterized by neurological symptoms …

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Headaches
Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in …

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Dementia
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders …

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Traumatic brain injury
Gaps in Access to Cognitive Rehabilitation Referrals Among Veterans with Mild Traumatic Brain Injury

by myneuronews December 12, 2025

by myneuronews December 12, 2025

Access Barriers to Rehabilitation Numerous obstacles can hinder veterans with mild traumatic brain injury (mTBI) …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Multimodal Canonical Correlation Analysis with Joint Independent Component Analysis (mCCA+jICA) of IVIM and ASL MRI Reveals Perfusion and Diffusion Abnormalities in mTBI-A Pilot Study
Mild traumatic brain injury (mTBI) frequently causes subtle brain changes that are difficult to detect with conventional diagnostic approaches. In this exploratory pilot study, we combined tri-exponential intravoxel incoherent motion (IVIM) and pseudocontinuous arterial spin labeling (pCASL) MRI with Multimodal Canonical Correlation Analysis and joint independent component analysis (mCCA+jICA) to identify imaging signatures distinguishing mTBI […]