Tag:

ImPACT

Functional neurological disorders
Modulation of conformational features and oligomerization of MMACHC by cobalamin variants: impact of the R161Q mutation in cblC disease

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Conformational Features of MMACHC The study delves into the conformational characteristics of MMACHC, a protein …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion Characteristics in Dyskinetic Cerebral Palsy In dyskinetic cerebral palsy, the distribution of lesions is …

Read more

0 Facebook Twitter Pinterest Email
Functional neurological disorders
Fecal Microbiota Transplantation from Noni Fruit Phenolic-Rich Extract Intervention Mouse Donors Ameliorates Lipid Metabolism Disorder by Regulating the FXR-FGF15 Pathway in a Gut Microbiota-Dependent Manner

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Effects of Noni Fruit Extract on Gut Microbiota The study on the effects of Noni …

Read more

0 Facebook Twitter Pinterest Email
Dementia
Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Background and Rationale The intersection of depression and Alzheimer’s disease (AD) has garnered increasing attention …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Clinical experience implanting a miniature externally powered vagus nerve stimulator

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This study investigates the clinical experience surrounding the implantation of a miniature externally …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
A Comparison of Quantitative Pupillometry and VOMS in Division 1 Female Soccer Players

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to compare the efficacy of two assessment methods—quantitative pupillometry and …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research investigates the impact of cannabidiol (CBD) on rats subjected to multiple …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Clinical experience implanting a miniature externally powered vagus nerve stimulator

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview This research focuses on the clinical application of a miniature, externally powered vagus …

Read more

0 Facebook Twitter Pinterest Email
Traumatic brain injury
Association between concomitant traumatic brain injury and unfavorable 1-year outcomes in patients with traumatic spinal cord injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation centered around the relationship between traumatic brain injury (TBI) and the …

Read more

0 Facebook Twitter Pinterest Email

Autologous bone marrow mononuclear cell administration for neurological sequelae after traumatic brain injury: a matched control study
Neurological sequelae after traumatic brain injury impair motor and behavioural functions, imposing a heavy burden on patients and society. Traditional treatments show limited efficacy, highlighting the need for advanced therapies. This study evaluated the safety and efficacy of intrathecal administration of bone marrow mononuclear cells for treating these sequelae. A matched control clinical trial was […]
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients
CONCLUSIONS: S100B and the GFAP/UCH-L1 combination demonstrated very high sensitivities, close to 100 %, with specificities of approximately 30 % for the diagnosis of intracranial lesions. Age-adjusted thresholds improve specificity in older patients, supporting their clinical implementation. This study also provides the first evidence that hemolysis significantly elevates UCH-L1 concentrations from 400 mg/L of hemoglobin.
Retired contact sports athletes with cognitive concerns: promoting lifelong brain health
There is widespread concern among former athletes about the link between head injury and dementia. Neurologists are increasingly assessing ex-contact sports athletes with cognitive and behavioural issues following repetitive head impacts and traumatic brain injury. Their assessment and management can be challenging due to the broad differential diagnosis, including psychiatric issues, trauma-related impairment and, in […]
Visible signs of possible concussion at the FIFA World Cup Qatar 2022: Independent review and inter-rater reliability
CONCLUSIONS: Visible signs of concussion categorized as "red flags" were infrequent, resulting in uncertain reliability. The frequency and reliability of visible signs categorized as "yellow flags" and "other signs" varied, with the visible signs "clutching of the head" and "slow to get up" occurring so frequently that their utility for identifying possible concussion in football […]
Non-immersive virtual reality for cognitive rehabilitation of individuals with severe acquired brain injury (VR-sABI): study protocol for a multicentric randomized controlled trial
BACKGROUND: After a severe acquired brain injury (sABI), individuals might experience mild-to-severe cognitive impairments. In these patients, cognitive rehabilitation is provided as early as possible, to take advantage of and guide brain plasticity. According to a restorative approach, traditional cognitive training (TCT) usually involves repeated paper-and-pencil exercises of increasing difficulty and targeting specific cognitive domains. […]