Tag:

ImPACT

Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease Insulin signalling pathways play a crucial role in numerous …

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Traumatic brain injury
Tranexamic acid vs. embolization of the meningeal artery as an adjunctive therapeutic regime to reduce the recurrence rate after surgical relief of chronic subdural hematomas (TABASCO)-a randomized controlled trial

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Study Overview The study aims to evaluate the effectiveness of tranexamic acid compared to embolization …

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Traumatic brain injury
The ecological validity of two novel non-immersive virtual reality tests of attention and executive functions in an mTBI population

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Study Overview The investigation centered on assessing the ecological validity of two innovative non-immersive virtual …

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Traumatic brain injury
The Use of Technology to Support Cognitive Diversity Among Older Adults

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Cognitive Diversity and Aging Cognitive diversity refers to the variety of ways in which individuals …

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Functional neurological disorders
Brain-Specific Gata4 Downregulation in Greywick Female Mice Models the Metabolic Subtype of Polycystic Ovary Syndrome

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Brain-Specific Gata4 Function in Metabolism Gata4 is a transcription factor known for its critical roles …

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Dementia
Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

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Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Metabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …

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Functional neurological disorders
Aberrant phase separation of two PKA RIbeta neurological disorder mutants leads to mechanistically distinct signaling deficits

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Aberrant Phase Separation Mechanisms The study explores the role of aberrant phase separation in two …

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Traumatic brain injury
Understanding Beliefs and Perceptions of Parents, Coaches, and Organizational Leaders toward Non-concussive Head Impact Exposure in Youth American Football

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Head Impact Exposure In youth American football, the term “head impact exposure” refers to …

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Functional neurological disorders
Seizures and Functional Deficits across Mendelian Disorders of Epigenetic Machinery: Differential Effects as a Function of Epigenetic Modifications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Mendelian Disorders Mendelian disorders are genetic conditions resulting from mutations in a single gene …

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Long-term neurological and psychiatric complications and vocational outcome after cerebral venous sinus thrombosis
Patient Characteristics The demographic profile of patients who experience cerebral venous sinus thrombosis (CVST) provides…
Reply to “Clarifying the Moderating Role of Socioeconomic Status on Amyloid-Related Gray Matter Atrophy”
Study Overview This study addresses the complex interactions between socioeconomic status (SES) and the neurobiological…
A Scoping Review of Measures Used to Assess Stress-Related Motor Dysfunction in Functional Movement Disorder
Assessment Methods Overview Assessing stress-related motor dysfunction in individuals with functional movement disorder (FMD) encompasses…
Hysterical disorders in patients with hematological diseases
Prevalence of Hysterical Disorders in Hematological Patients The intersection of hematological diseases and hysterical disorders…
Indigenizing paediatric concussion injury prevention
Indigenous Perspectives on Concussion Understanding concussion within Indigenous communities requires a deep appreciation of cultural…

Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients
CONCLUSIONS: S100B and the GFAP/UCH-L1 combination demonstrated very high sensitivities, close to 100 %, with specificities of approximately 30 % for the diagnosis of intracranial lesions. Age-adjusted thresholds improve specificity in older patients, supporting their clinical implementation. This study also provides the first evidence that hemolysis significantly elevates UCH-L1 concentrations from 400 mg/L of hemoglobin.
Retired contact sports athletes with cognitive concerns: promoting lifelong brain health
There is widespread concern among former athletes about the link between head injury and dementia. Neurologists are increasingly assessing ex-contact sports athletes with cognitive and behavioural issues following repetitive head impacts and traumatic brain injury. Their assessment and management can be challenging due to the broad differential diagnosis, including psychiatric issues, trauma-related impairment and, in […]
Visible signs of possible concussion at the FIFA World Cup Qatar 2022: Independent review and inter-rater reliability
CONCLUSIONS: Visible signs of concussion categorized as "red flags" were infrequent, resulting in uncertain reliability. The frequency and reliability of visible signs categorized as "yellow flags" and "other signs" varied, with the visible signs "clutching of the head" and "slow to get up" occurring so frequently that their utility for identifying possible concussion in football […]
Non-immersive virtual reality for cognitive rehabilitation of individuals with severe acquired brain injury (VR-sABI): study protocol for a multicentric randomized controlled trial
BACKGROUND: After a severe acquired brain injury (sABI), individuals might experience mild-to-severe cognitive impairments. In these patients, cognitive rehabilitation is provided as early as possible, to take advantage of and guide brain plasticity. According to a restorative approach, traditional cognitive training (TCT) usually involves repeated paper-and-pencil exercises of increasing difficulty and targeting specific cognitive domains. […]
What traditional neuropsychological assessment got wrong about mild traumatic brain injury. III: the added value of advanced neuroimaging
CONCLUSIONS: Characterizations from traditional neuropsychological measures as independent tests indicating no lasting sequelae from mTBI, especially after three-months post-injury from mTBI need to be viewed within the context of what advanced neuroimaging can demonstrate. Future directions involving the integration of advanced neuroimaging developments applicable to the mTBI patient are reviewed, especially when integrated with neuropsychological […]