The Connections Between Pain and Itch: Shared Neuroimmune Mechanisms and Therapeutic Implications
Shared Neuroimmune Mechanisms The interplay between the nervous system and the immune system plays a crucial role in understanding the […]
P2X4 Drives Sex-Specific neuroprotection in autoimmune neuroinflammation
Mechanisms of P2X4 in Neuroprotection The P2X4 receptor, a member of the purinergic receptor family, has emerged as a key
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Patient profiles and disease characteristics of the IMSRN cohort: a multicentre study (2021-2025)
Patient Demographics The IMSRN cohort comprises a diverse group of individuals, reflecting a wide range of ages, genders, and ethnic
The neural transdifferentiation potential of bone marrow mesenchymal stem cells
Neural Transdifferentiation Mechanisms The process of neural transdifferentiation in bone marrow mesenchymal stem cells (BM-MSCs) involves a series of intricate
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Optic chiasmal neuritis: clinical features, aetiologies, MRI patterns and prognosis in a real-world cohort
Clinical Features and Presentation Optic chiasmal neuritis is characterized by a variety of clinical features that can significantly impact a
Failure of early B cell tolerance and possible BCR signaling dysregulation underlie NF155-mediated autoimmune nodopathies
Mechanisms of B Cell Tolerance Failure B cell tolerance is a critical mechanism that prevents the activation of autoreactive B
The association of multiple sclerosis with systemic inflammatory biomarkers: A case-control study exploring links with periodontal disease
Study Overview This case-control study investigates the relationship between multiple sclerosis (MS) and systemic inflammatory biomarkers, focusing on potential connections
Case report: Unilateral optic atrophy and intracranial hypertension in anti-NF155 nodopathy: a case managed with sequential efgartigimod and rituximab
Clinical Presentation The case in question involved a patient diagnosed with unilateral optic atrophy and intracranial hypertension, specifically linked to
A Clinical Profile of Transverse Myelitis with Special Reference to Outcomes: A 5-Year Retrospective Study
Study Overview This research undertakes an extensive evaluation of transverse myelitis (TM), a rare neurological condition characterized by inflammation of
Surprising epileptic semiology in seventeenth-century beatification testimonies: A neuropsychiatric analysis of St. Joseph of Copertino
Contextualizing Seventeenth-Century Beatification The process of beatification during the seventeenth century was deeply intertwined with the spiritual and social fabric