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Functional neurological disorders
Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Clinical Characteristics of the New Brunswick Neurological Syndrome The New Brunswick Neurological Syndrome (NBNS) has …

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Traumatic brain injury
Self-Reported Cognitive Difficulties and Their Modifiable Risk Factors in Former Elite Male Rugby League Players

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Background and Context Rugby league is a physically demanding sport that subjects players to repetitive …

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Functional neurological disorders
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Cholinergic Pathways in Parkinson’s Disease In the context of Parkinson’s disease, understanding the role of …

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Functional neurological disorders
Physical-functional alterations in women with chronic migraine

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Physical-functional alterations in chronic migraine Chronic migraine is a debilitating condition that can lead to …

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Functional neurological disorders
Physical-functional alterations in women with chronic migraine

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Understanding chronic migraine in women Chronic migraine is a complex and debilitating neurological condition that …

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Movement Disorders
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Study Overview The prevalence of migraine, a debilitating neurological condition characterized by severe headaches often …

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Headaches
Diagnosing migraine from genome-wide genotype data: a machine learning analysis

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Background on Migraine and Genomics Migraine is a prevalent and often debilitating neurological condition characterized …

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Traumatic brain injury
An 18-Year Study of Changes in Neurocognitive Function and Associations with Repetitive Head Trauma among Former Collegiate American Football Players: A Case Series

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Study Overview This comprehensive investigation delves into the long-term effects of repetitive head trauma on …

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Traumatic brain injury
Dietary supplementation roles in concussion management: A systematic review

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Supplementation Strategies in Concussion Care Various nutritional strategies have been proposed as adjuncts to traditional …

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Traumatic brain injury
An 18-Year Study of Changes in Neurocognitive Function and Associations with Repetitive Head Trauma among Former Collegiate American Football Players: A Case Series

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Background and Rationale The interplay between repetitive head trauma and long-term neurocognitive health has become …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.