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Functional neurological disorders
Seizures and Functional Deficits across Mendelian Disorders of Epigenetic Machinery: Differential Effects as a Function of Epigenetic Modifications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Mendelian Disorders Mendelian disorders are genetic conditions resulting from mutations in a single gene …

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Functional neurological disorders
The early-life gut microbiome in common pediatric diseases: roles and therapeutic implications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Early-life gut microbiome and pediatric diseases The human gut is populated by trillions of microorganisms, …

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Traumatic brain injury
Protocol of a randomized, single-blind, controlled trial of an 18-month, home-based, high-intensity, exercise intervention in older, cognitively unimpaired APOE ε4 carriers

by myneuronews June 11, 2025

by myneuronews June 11, 2025

Study Overview This trial is meticulously designed to assess the effectiveness of a high-intensity, home-based …

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Traumatic brain injury
Impacts of traumatic brain injury severity and sex on sleep architecture, duration, and fragmentation

by myneuronews June 11, 2025

by myneuronews June 11, 2025

Impact of Traumatic Brain Injury Severity Traumatic brain injury (TBI) is a complex condition that …

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Dementia
One size does not fit all: how type of menopause and hormone therapy matters for brain health

by myneuronews June 9, 2025

by myneuronews June 9, 2025

Menopause Types and Their Impact Menopause is a significant transition in a woman’s life, marked …

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Headaches
Cardiac cephalalgia-headache as an atypical presentation of ST-segment elevation myocardial infarction: a case report

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Study Overview This case report centers on a unique presentation of ST-segment elevation myocardial infarction …

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Dementia
Plasma biomarkers for early detection of alzheimer’s disease: a cross-sectional study in a Japanese cohort

by myneuronews June 7, 2025

by myneuronews June 7, 2025

Study Overview This research focuses on identifying plasma biomarkers that can facilitate the early detection …

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Traumatic brain injury
Widespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury

by myneuronews June 6, 2025

by myneuronews June 6, 2025

Transcriptomic Changes Induced by Injury Mild traumatic brain injury (mTBI) triggers significant changes in the …

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Headaches
Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury

by myneuronews June 5, 2025

by myneuronews June 5, 2025

Long-term outcomes Long-term outcomes in patients with leucine-rich glioma inactivated-1 (LGI1) autoimmune encephalitis are a …

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Traumatic brain injury
Cognitive functioning following mild stroke in adults aged 18 to 64 years: association with participation

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Cognitive Impacts of Mild Stroke Following a mild stroke, individuals often experience various cognitive impairments …

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Midlife plasma proteomic profiles indicate altered amyloid and tau processing in former elite rugby players
CONCLUSIONS: Ex-players showed distinctive plasma biomarker changes, more prominently in ex-forwards, possibly reflecting greater RHI exposure. Plasma KLK6, an endothelial serine protease, was reduced across the ex-player group, with potential diagnostic or prognostic utility in future. Reduced GFAP and SNAP25 in ex-forwards has an uncertain basis, while elevated p-tau-(181) more so than p-tau(217) points towards […]
A Guide to the Interpretation and Reliability of Annual Collegiate ImPACT Baselines by Sex
CONCLUSIONS: This study found sex differences on ImPACT performance, suggesting that sex-specific MDC values are needed to evaluate significant changes in ImPACT scores. Additionally, this study found several ImPACT subtest scores to be unreliable, suggesting only moderate to good scores be used in clinical evaluation.
<em>Taking Control of Your Functional Cognitive Symptoms: Workbook</em>-A Novel Intervention
CONCLUSIONS: This promising new multimodality behavioral health intervention can be considered to be in stage 1 (i.e., intervention generation, refinement, modification, adaptation, and pilot testing). Further pilot testing is being conducted and will need to be followed by traditional efficacy testing (in stage 2).
Hemodynamic Oscillations in Mild TBI During Postural Change: An fNIRS Pilot Study
We demonstrate that low-frequency oscillations (LFOs) in cerebral hemodynamics, measured by frequency-domain functional near-infrared spectroscopy (FD-fNIRS), reflect altered cerebral hemodynamic oscillations in mild traumatic brain injury (mTBI). In a pilot study of two mTBI and 13 healthy subjects undergoing head-of-bed positional changes, we analyzed total hemoglobin concentration (THC), oxyhemoglobin (HbO), and deoxyhemoglobin (Hb) dynamics using […]
Normative Data for Single- and Dual-Task Tandem Gait Performance in Collegiate Athletes
CONCLUSION: Our results provide robust normative data for single- and dual-task tandem gait stratified by relevant patient factors that can be immediately used by clinicians and future researchers. Future research should compare the use of individual baseline versus normative data for acute concussion tracking.