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Functional neurological disorders
Hypoxic preconditioning modulates BDNF signaling to alleviate depression-like behaviors in mice and its whole transcriptome sequencing analysis

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Mechanisms of Hypoxic Preconditioning Hypoxic preconditioning (HP) is an intriguing physiological process whereby exposure to …

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Traumatic brain injury
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories show Trend of Recovery for Deployment-related mild TBI in the LIMBIC-CENC Cohort

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Cognitive Recovery Patterns The journey of cognitive recovery following a mild traumatic brain injury (mTBI) …

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Traumatic brain injury
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories show Trend of Recovery for Deployment-related mild TBI in the LIMBIC-CENC Cohort

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Longitudinal Cognitive Trajectories The concept of longitudinal cognitive trajectories is critical in understanding how cognitive …

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Functional neurological disorders
Personality assessment inventory sex differences in people with epileptic and functional seizures

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Personality Traits in Epileptic Seizures The examination of personality traits among individuals experiencing epileptic seizures …

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Traumatic brain injury
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background on PACAP and Inflammation Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays …

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Functional neurological disorders
Expanding the spectrum of ATP8A2 mutations: a new splicing variant and systematic review of CAMRQ4 syndrome

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Identifying New ATP8A2 Mutations ATP8A2 mutations have garnered significant attention in recent years due to …

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Functional neurological disorders
Personality assessment inventory sex differences in people with epileptic and functional seizures

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Overview of Personality Assessment Inventory The Personality Assessment Inventory (PAI) is a psychological assessment tool …

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Traumatic brain injury
Associations of Collegiate Football Career and Incident Concussion with Players’ Health: A Longitudinal Study from the CARE Consortium

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background and Rationale In recent years, the growing concern surrounding sports-related concussions has prompted educators, …

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Stroke
Proteome-Wide Genetic Study in East Asians and Europeans Identified Multiple Therapeutic Targets for Ischemic Stroke

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Genetic Insights into Ischemic Stroke Ischemic stroke, a condition where blood flow to the brain …

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Movement Disorders
Arteriolosclerosis in CNS Tissues Outside the Cerebrum and Late-Life Motor Impairment

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Arteriolosclerosis in Non-Cerebral CNS Regions Arteriolosclerosis, a condition characterized by the thickening and hardening of …

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Multidisciplinary rehabilitation and follow-up for children hospitalized with traumatic brain injury
PurposeMost children hospitalized with traumatic brain injury (TBI) acquire new impairments that impact function and health-related quality of life. However, there is a lack of standardized, multidisciplinary, longitudinal rehabilitative services for children with TBI.MethodsThis single center, retrospective study evaluated rehabilitative services during acute hospitalization and identified the frequency of unmet needs, defined as new or […]
Decreased IL-33 in the brain following repetitive mild traumatic brain injury contributes to cognitive impairment by inhibiting microglial phagocytosis
CONCLUSIONS: Dysfunction of the IL-33/ST2 axis following rmTBI leads to cognitive dysfunction via impairing microglial phagocytosis capacity and promoting neuronal damage. IL-33 would be a promising therapeutic target for alleviating neurodegeneration following rmTBI.
Tackle characteristics associated with concussion in elite men's rugby union: unpicking the differences between tacklers and ball-carriers
CONCLUSIONS: Lower tackles reduce the chances of concussion to ball-carriers. The influence of tackle height on concussion to tacklers is more nuanced, but the chances are relatively low when contact is made with the ball-carrier's torso. These findings support ongoing implementation of strategies to reduce concussion risk by lowering tackle height to target the torso.
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model
Repetitive mild traumatic brain injury (rmTBI) is a major contributor to long-term neurological dysfunction, yet many preclinical models lack precise control and quantification of biomechanical forces across impacts. We developed a reproducible, closed-skull mouse model of rmTBI using a custom-built weight-drop apparatus featuring a solenoid-based rebound arrest system, integrated high-speed videography, and accelerometry to track […]
Sport-Related Concussion Knowledge in French-Speaking Athletes, Coaches, and Health Care Professionals: Results From an International Survey on 2073 Participants
CONCLUSIONS: Knowledge translation strategies should be adapted to better reach the French-speaking sports community in Europe and further individualized according to professional role.