Tag:

longitudinal studies

Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Traumatic brain injury
Correction: Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Cerebral haemodynamics in concussion Cerebral haemodynamics refers to the dynamics of blood flow within the …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Traumatic brain injury
A systematic review and meta-analysis of sleep following mild traumatic brain injury: A synthesis of the literature according to age and time-since-injury

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Effect of Age on Sleep Post-Injury The relationship between age and sleep disturbances following a …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological tau phosphorylation mechanisms Tau is a critical protein in the brain, primarily known for …

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Traumatic brain injury
Exploring trends in pediatric craniofacial furniture accidents: Implications for prevention, safety counseling, and future advocacy initiatives

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Trends in Pediatric Craniofacial Furniture Accidents Over the past several years, there has been a …

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Traumatic brain injury
A systematic review and meta-analysis of sleep following mild traumatic brain injury: A synthesis of the literature according to age and time-since-injury

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Overview of Sleep Disruptions Sleep disruptions represent a common and often underestimated consequence following mild …

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Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Movement Disorders
The prodromal individuals’ perspective on active recruitment for early detection of α-synucleinopathies

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Perspective of Prodromal Individuals The perspective of individuals in the prodromal stage of α-synucleinopathies sheds …

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Stroke
“Low-to-moderate arsenic exposure: a global systematic review of cardiovascular disease risks”

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Epidemiological Context The issue of arsenic exposure and its potential links to cardiovascular diseases is …

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Traumatic brain injury graphing: A case study of Charles Whitman
Research has identified violent behavior (i.e., assault, murder, and suicide) as a possible sequela of moderate to severe traumatic brain injury (TBI) and repeated mild TBI (rmTBI). However, misconceptions about consciousness and its ability to control an injured brain, the diverse spectrum of potential outcomes, and the role genetics/environmental factors can play make proving TBI's […]
Injury Prevention Programs in Youth Football: A Narrative Review of the FIFA 11+ and FUNBALL Programs
Football (soccer) is a dynamic sport popular among youth, but it poses risks of injuries such as ligament tears, fractures, and concussions. Injury prevention programs are essential for safeguarding young athletes' health and performance. This review evaluates two key programs: the 11+ and FUNBALL. The 11+ program is a structured warm-up designed for young female […]
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory
Every time a person sustains a blow to the head, they receive multiple atypical sensory inputs, often including pain. These directly stimulate the central nervous system. Yet, sensory input as a causal agent of neurophysiological dysfunction and post-concussion symptoms has never been explored. A new theory is proposed of sensory driven neurophysiological mechanisms of concussion […]
Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury
Although tumor necrosis factor-alpha (TNF-α) plays an important role in the development of obsessive-compulsive disorder (OCD), the pathogenesis remains unclear. Since transient receptor potential melastatin 3 (TRPM3) channels are activated during inflammatory conditions, crosstalk with TNF-α in the progression of OCD has not been investigated yet. We hypothesize that mild traumatic brain injury (mTBI) stimulates […]
Age-Adjusted Cut-Off Values for Glial Fibrillary Acidic Protein and Ubiquitin Carboxy-Terminal Hydrolase L1 Improve the Diagnostic Accuracy of the Abbott Mild Traumatic Brain Injury Assay
Objectives: To establish age-adjusted cut-off values for glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and assess their impact on the diagnostic performance of the mild traumatic brain injury (mTBI) assay. Methods: The study included 175 adult mTBI patients presenting at the emergency department (ED) within 12 h from head trauma in […]