Tag:

longitudinal studies

Functional neurological disorders
OCNDS core features are conserved across variants, with loop-region mutations driving greater symptom burden

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Core Features of OCNDS OCNDS, or Operationally Defined Neurological Disorder Spectrum, presents a fascinating array …

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Traumatic brain injury
Examining the potential of psilocybin and 5-MeO-DMT as therapeutics for traumatic brain injury

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Therapeutic Mechanisms of Psilocybin and 5-MeO-DMT Psilocybin and 5-MeO-DMT, both naturally occurring psychedelic compounds, have …

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Traumatic brain injury
Brain biomarker profiles vary with semi-synthetic and grain-based diets in healthy and mTBI mice

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Brain Biomarker Profiles Recent studies have highlighted the importance of brain biomarker profiles in understanding …

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Functional neurological disorders
Shared neural signatures in Functional Neurological Disorder and Chronic Pain: a multimodal narrative review

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Neural Mechanisms in FND and Chronic Pain Research into the neural mechanisms underlying Functional Neurological …

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Traumatic brain injury
Exploring the diagnostic and prognostic utility of resting state functional MRI connectivity in acute/sub-acute TBI

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Diagnostic Utility of Resting State fMRI Resting state functional magnetic resonance imaging (fMRI) has emerged …

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Functional neurological disorders
Transcranial magnetic stimulation as a primer for rapid improvement in functional neurological disorder: a case series

by myneuronews July 15, 2025

by myneuronews July 15, 2025

Transcranial Magnetic Stimulation Overview Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique that uses …

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Traumatic brain injury
MILD TRAUMATIC BRAIN INJURY IMPAIRS EPISODIC MEMORY IN RATS

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Study Overview The research investigates how mild traumatic brain injury (mTBI) affects episodic memory in …

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Functional neurological disorders
A scoping review of studies on dissociative and conversion disorders in India

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Overview of Dissociative and Conversion Disorders Dissociative and conversion disorders represent complex and often misunderstood …

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Traumatic brain injury
Attention-Deficit/Hyperactivity Disorder as a Mediating Variable for Invalid Baseline Profiles on the ImPACT

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Study Overview The research investigates the role of Attention-Deficit/Hyperactivity Disorder (ADHD) as a mediating factor …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Boston University Alzheimer's Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer's disease and related dementias
We describe the rationale, methodology, and design of the Boston University Alzheimer's Disease Research Center (BU ADRC) Clinical Core (CC). The CC characterizes a longitudinal cohort of participants with/without brain trauma to characterize the clinical presentation, biomarker profiles, and risk factors of post-traumatic Alzheimer's disease (AD) and AD-related dementias (ADRD), including chronic traumatic encephalopathy (CTE). […]
Acute effects of sport-related concussion among adolescents with a self-reported history of treatment for anxiety or depression
Objective: This study compared symptom reporting and cognitive test performance within 72 h of a suspected concussion between high school student-athletes with and without pre-injury self-reported mental health treatment. Methods: Eight hundred seventy-nine high school athletes with (n = 75) and without (n = 804) a self-reported history of treatment for anxiety or depression underwent […]
Sensory processing patterns in pediatric mild traumatic brain injury: A longitudinal study
Sensory processing (SP) difficulties, such as heightened sensitivity to sensory input, have been linked to prolonged recovery and persistent post-concussive symptoms in adults following mild traumatic brain injury (mTBI). However, research on SP across different sensory inputs after pediatric mTBI is limited. This study examined SP patterns in children and adolescents aged 6-17 years with […]
Cervical spine and vestibulo-ocular screening in elite female athletes with a history of concussion
CONCLUSIONS: The results of this study suggest that athletes with a history of concussion should undergo manual assessment of the cervical spine and vestibulo-ocular system screening regardless of baseline self-reported symptom profile.
Progressive lifespan modifications in the corpus callosum following a single concussion in juvenile male mice monitored by diffusion MRI
CONCLUSION: For the first time, we demonstrate progressive perturbations to WM of male mice after a single juvenile concussion across their lifespan. The CC alterations were dependent on concussion severity with elevated sensitivity in the anterior CC that was related to astrocyte and microglial morphology changes. Our findings suggest that long-term monitoring of children with […]