Tag:

longitudinal studies

Traumatic brain injury
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories show Trend of Recovery for Deployment-related mild TBI in the LIMBIC-CENC Cohort

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Cognitive Recovery Patterns The journey of cognitive recovery following a mild traumatic brain injury (mTBI) …

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Traumatic brain injury
Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Cerebral haemodynamic changes Cerebral haemodynamics refers to the flow of blood in the brain and …

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Traumatic brain injury
Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Impact of Collision Sports on Neurodegenerative Risk Participation in collision sports can have significant implications …

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Functional neurological disorders
Expanding the spectrum of ATP8A2 mutations: a new splicing variant and systematic review of CAMRQ4 syndrome

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Overview of ATP8A2 and CAMRQ4 Syndrome ATP8A2 is a gene that encodes a protein crucial …

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Traumatic brain injury
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background on PACAP and Inflammation Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays …

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Functional neurological disorders
Personality assessment inventory sex differences in people with epileptic and functional seizures

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Overview of Personality Assessment Inventory The Personality Assessment Inventory (PAI) is a psychological assessment tool …

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Traumatic brain injury
Associations of Collegiate Football Career and Incident Concussion with Players’ Health: A Longitudinal Study from the CARE Consortium

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background and Rationale In recent years, the growing concern surrounding sports-related concussions has prompted educators, …

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Traumatic brain injury
Clinical Characteristics and Outcomes of Pediatric Traumatic Brain Injury Patients in a Tertiary Regional Trauma Center in the Philippines

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Patient Demographics and Injury Mechanisms The study cohort comprised pediatric patients who sustained traumatic brain …

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Traumatic brain injury
PIRACETAM HELPS RESTORE VISION AFTER CRANIOCEREBRAL TRAUMA

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Piracetam Mechanism of Action Piracetam, a member of the racetam family of nootropic compounds, is …

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Functional neurological disorders
Autoimmune psychosis: Psychopathological patterns and outcome after immunotherapy

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Autoimmune Psychosis Overview Autoimmune psychosis is an emerging area of interest in neurology and psychiatry, …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.