Tag:

longitudinal studies

Traumatic brain injury
Use of physical exertion to enhance objective testing following mild traumatic brain injury: a systematic review

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Physical Exertion as a Rehabilitation Strategy Physical exertion has gained recognition as a potential rehabilitative …

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Stroke
Increased Risk of Myocardial Infarction in Inclusion Body Myositis: A Non-Concurrent Cohort Study

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Cardiovascular Risk Factors in Inclusion Body Myositis The relationship between inclusion body myositis (IBM) and …

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Traumatic brain injury
Clinical Cut Point for the Pittsburgh Sleep Quality Index After Adolescent Concussion

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Clinical Relevance of Sleep Quality Sleep quality is a pivotal aspect of overall health and …

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Functional neurological disorders
Neuroimaging Biomarkers of Post-acute Sequelae of Covid (PASC)

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Neuroimaging Techniques and PASC Neuroimaging techniques have emerged as powerful tools in understanding the neurological …

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Dementia
FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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Traumatic brain injury
Retinal manifestations of traumatic brain injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Retinal Changes Associated with Traumatic Brain Injury Traumatic brain injury (TBI) can lead to various …

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Traumatic brain injury
Psychological interventions for externalising behaviours following paediatric traumatic brain injury: a systematic review and clinical practice recommendations

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Overview of Externalising Behaviours Externalising behaviours refer to a range of actions that move outwardly, …

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Stroke
Everyday moderate-to-vigorous physical activity in stroke survivors: the role of individual and joint intentions and self-efficacy

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Study Overview This investigation centered on understanding the dimensions of physical activity among stroke survivors, …

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Dementia
Resistance and resilience to Alzheimer’s disease in Down syndrome

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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Traumatic brain injury
Concussions Are Associated With Increases in Blood Pressure and Cardiovascular Risk in American-Style Football Athletes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Impact of Concussions on Cardiovascular Health Recent research has highlighted a concerning link between concussions …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.