Tag:

machine learning

Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion Characteristics in Dyskinetic Cerebral Palsy In dyskinetic cerebral palsy, the distribution of lesions is …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

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Functional neurological disorders
Circulating inflammatory proteins as pathogenic mediators and potential therapeutic targets in myasthenia gravis

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Pathogenic Role of Inflammatory Proteins In recent studies, inflammatory proteins have emerged as key players …

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Functional neurological disorders
Regional structural differences in the brain related to high blood pressure

by myneuronews June 23, 2025

by myneuronews June 23, 2025

Regional Brain Changes Associated with Hypertension High blood pressure, or hypertension, has been shown to …

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Traumatic brain injury
Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury

by myneuronews June 22, 2025

by myneuronews June 22, 2025

Injury-Specific Proteomic Signatures In recent research, a growing body of evidence has revealed that distinct …

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Functional neurological disorders
Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Resting-State Brain Activity in Adolescents Resting-state brain activity refers to the spontaneous brain fluctuations that …

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Dementia
Crossing the ‘Cookie Theft’ Corpus Chasm: Applying what BERT Learns from Outside Data to the ADReSS Challenge Dementia Detection Task

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Study Overview The study investigates the intersection between artificial intelligence and dementia detection by utilizing …

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Headaches
Combination behavioral and pharmacological interventions through telehealth platforms: Opportunities for increasing access and optimizing migraine outcomes

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Telehealth Integration for Migraine Management The integration of telehealth into migraine management represents a significant …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Functional neurological disorders
Practicing With a Framework Mindset: A Closer Look at the Principle of Quality Improvement

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Quality Improvement Framework Quality improvement (QI) is an essential aspect of enhancing healthcare delivery, particularly …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]