Tag:

machine learning

Functional neurological disorders
Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Understanding Mild Cognitive Impairment Heterogeneity Mild cognitive impairment (MCI) is a clinical condition that marks …

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Functional neurological disorders
In-silico analysis of deleterious non-synonymous SNPs in the human AVPR1a gene linked to autism

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Significance of AVPR1a Gene in Autism The AVPR1a gene, which encodes the arginine vasopressin receptor …

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Functional neurological disorders
Progress in the Management of Mediastinal Ectopic Parathyroid Adenomas: The Role of Minimally Invasive Surgery

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Advancements in Minimally Invasive Techniques In recent years, there has been an impressive evolution in …

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Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Functional neurological disorders
A perspective on NiCo2O4-based photocatalysts: from fundamentals, modification strategies to applications

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Overview of NiCo2O4 Photocatalysts NiCo2O4 is emerging as a promising material in the realm of …

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Functional neurological disorders
Steric Hindrance-Induced Amorphous Lithium Sulfide Deposition Accelerates Sulfur Redox Kinetics in Lithium-Sulfur Batteries

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Mechanism of Steric Hindrance in Lithium Sulfide Deposition The deposition of lithium sulfide (Li2S) is …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Functional neurological disorders
Automated seizure detection in epilepsy using a novel dynamic temporal-spatial graph attention network

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Methodology and Model Architecture The study introduces a sophisticated machine learning approach aimed at enhancing …

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Functional neurological disorders
Handwriting, touchscreen dexterity and bradykinesia measures in Parkinson’s disease: a feature selection study

by myneuronews May 11, 2025

by myneuronews May 11, 2025

Background on Parkinson’s Disease and Motor Symptoms Parkinson’s disease is a progressive neurodegenerative disorder primarily …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]