Tag:

management

Traumatic brain injury
Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries – A systematic review of the literature by the IMPACT group

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview This systematic review focuses on the timing of definitive fracture fixation in patients …

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Traumatic brain injury
Impact of Modified Brain Injury Guideline Incorporating Neurosurgical Consultation on Resource Utilization and Follow-Up Care in Complicated Mild Traumatic Brain Injury

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview This investigation centers on the outcomes associated with the implementation of an updated …

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Traumatic brain injury
The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure

by myneuronews October 28, 2025

by myneuronews October 28, 2025

Study Overview The investigation focused on the potential effects of previous concussions and engagement in …

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Traumatic brain injury
Sport, healthcare and educational organisations’ perceptions of a framework for managing concussion in New Zealand schools: a qualitative study

by myneuronews October 27, 2025

by myneuronews October 27, 2025

Framework Overview The framework for managing concussion in New Zealand schools is a structured guideline …

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Traumatic brain injury
Telerehabilitation for mild traumatic brain injury patients: patients’ preferences in Aotearoa New Zealand

by myneuronews October 27, 2025

by myneuronews October 27, 2025

Patient Preferences Understanding patient preferences in the context of telerehabilitation for mild traumatic brain injury …

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Dementia
Sex-related disparities in cognitive impairment in kidney transplant patients with kidney failure

by myneuronews October 26, 2025

by myneuronews October 26, 2025

Study Overview This research explores the cognitive impairment experiences of kidney transplant patients suffering from …

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Headaches
CD39(+) CD4(+) T Cells Influence Cluster Headache Risk via ADP/N-Acetylneuraminate and Choline Metabolic Pathways: Evidence from Mendelian Randomization

by myneuronews October 26, 2025

by myneuronews October 26, 2025

Study Overview This research investigates the influence of CD39(+) CD4(+) T cells on the risk …

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Traumatic brain injury
Factor analysis of neuropsychological attention measures with mild traumatic brain injury patients

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Study Overview This research investigates how various neuropsychological measures of attention are affected in patients …

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Dementia
Cerebral amyloid angiopathy-related inflammation superimposed on alpha-synucleinopathies: a case report and literature review

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Study Overview This case report examines the complex relationship between cerebral amyloid angiopathy (CAA) and …

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Headaches
Adverse event reporting and management in psilocybin therapy clinical trials: A systematic review to guide clinical and research protocol development

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Study Overview The exploration of adverse events related to psilocybin therapy within clinical trials has …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]