Tag:

metabolomics

Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

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Traumatic brain injury
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators

by myneuronews November 5, 2025

by myneuronews November 5, 2025

Understanding Traumatic Brain Injury Severity Traumatic brain injury (TBI) manifests in varying degrees of severity, …

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Dementia
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis

by myneuronews October 30, 2025

by myneuronews October 30, 2025

Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained …

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Traumatic brain injury
Brain-derived exosomes from aged mice accelerate cognitive decline in repeated mild traumatic brain injury by activating neuronal Tnfrsf25

by myneuronews October 18, 2025

by myneuronews October 18, 2025

Exosome Characteristics Exosomes are small extracellular vesicles that range from 30 to 150 nanometers in …

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Traumatic brain injury
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice

by myneuronews October 9, 2025

by myneuronews October 9, 2025

Study Overview This study investigates the effects of exercise on molecular changes following a mild …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Headaches
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Metabolite Profile Changes Upon infection with the tick-borne encephalitis virus (TBEV), significant alterations occur in …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Supernatural-Functiolistic-Expialidocious: A Comparative Study Between Functional Neurological Symptom Disorder/Conversion Disorder and Other Psychiatric Conditions
Study Overview The research undertaken explores the complex interplay between Functional Neurological Symptom Disorder (FND),…
Diagnostic labels in functional disorders
Understanding Functional Disorders Functional disorders encompass a range of conditions where patients experience symptoms that…
Intraoperative Electroneurography (ENoG) of Facial Nerve Conduction during Mandibular Distraction Osteogenesis for Robin Sequence
Study Overview The study investigates the efficacy and safety of intraoperative electroneurography (ENoG) as a…
Implementation of Virtual Reality for Postoperative Recovery in an Adolescent Idiopathic Scoliosis Population: a Prospective Pilot Study
Study Overview This study investigates the implementation of virtual reality (VR) as a tool to…
The Impact of Hearing Loss on Annual Incident Age-Associated Dementia Cases and Quality of Life in the US
Impact of Hearing Loss on Dementia Incidence Hearing loss has emerged as a significant risk…

Defining significant acute traumatic intracranial injuries in adult patients with traumatic brain injury: a narrative review
CONCLUSION: To date, there is no contemporary consensus definition of a significant acute traumatic intracranial lesion in patients presenting with TBI. Several factors appear essential for defining a significant lesion, including comorbidities, clinical presentation, CT scan injury characteristics and biomarkers.
Relationship Between Sport Specialization and Short-Term Health-Related Quality of Life in Youth Athletes After Injury
CONCLUSION: Higher level of sport specialization is not associated with worse HRQoL approximately 1 month after sport-related injury. Female athletes have worse short-term HRQoL after an injury irrespective of sport specialization level. While sex differences were statistically significant, the magnitude of differences was small.
Behavioral treatment of insomnia in active-duty service members with traumatic brain injury: study protocol for a randomized clinical trial
BACKGROUND: Traumatic brain injury (TBI) in the U.S. military can result in lasting health issues, with insomnia being a common symptom that worsens recovery, cognitive function, and performance, especially when combined with common co-occurring conditions like chronic pain, post-traumatic stress disorder (PTSD), and depression. Insomnia may be an important intervention target for managing post-concussive symptoms […]
A population-based study of traumatic brain injury incidence and mechanisms in New Zealand: 2021-2022 compared with 2010-2011
BACKGROUND: Monitoring traumatic brain injury (TBI) incidence and epidemiological patterns is important for evidence-based strategic planning, policy, prevention, and resource allocation. We revisited population-based estimates and examined patterns of TBI incidence (all ages, severities) in 2021-2022 compared with 2010-2011 in New Zealand (NZ).
Completion of massive open online course improved knowledge about traumatic brain injury globally
CONCLUSION: The Understanding TBI MOOC improved survey scores across all demographics and experiences indicating that the MOOC is an effective tool to improve knowledge about TBI in the community.