Tag:

migraines

Headaches
The P2Y13 receptor-mediated microglial morphological transformation through the p38MAPK signaling pathway contributes to central sensitization in a murine model of chronic migraine

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Study Overview The primary objective of this research was to investigate the role of the …

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Headaches
Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis

by myneuronews December 13, 2025

by myneuronews December 13, 2025

Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in …

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Headaches
Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research investigates the similarities and differences between vestibular migraine and typical migraine …

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Headaches
The use of triptans and other acute treatments for the management of migraine in routine clinical practice in England: a retrospective cohort study using the Clinical Practice Research Datalink (CPRD)

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview This research investigated the utilization of triptans and other immediate treatment options for …

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Headaches
Harnessing the power of plant gums: A detailed review of their bioactive compounds and therapeutic benefits

by myneuronews December 7, 2025

by myneuronews December 7, 2025

Bioactive Compounds in Plant Gums Plant gums are complex polysaccharides produced by various plant species, …

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Headaches
Co-production and validation of an online resource to support the diagnosis of migraine

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Resource Development The development of the online resource aimed at aiding the diagnosis of migraine …

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Headaches
Interoception in migraine is characterised by normal accuracy but altered sensibility and behaviour

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Interoception and Migraine Interoception refers to the ability to perceive internal bodily states, which plays …

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Traumatic brain injury
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Study Overview This comprehensive review focuses on the advances in the management of acute migraine …

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Headaches
Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of …

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Headaches
Symptoms of allodynia and pain thresholds amongst those with acute post-traumatic headache attributed to mild traumatic brain injury: a prospective, longitudinal study

by myneuronews November 29, 2025

by myneuronews November 29, 2025

Study Overview This research investigates the presence of allodynia, a condition where normally non-painful stimuli …

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Evaluation of sport-related concussion factors at baseline in a cohort of collegiate rugby union players
Sport-related concussion (SRC) is a growing concern in Rugby Union (RU) and SRC's relationship to intrinsic and extrinsic factors is unknown. A descriptive cross-sectional design was used to describe the relationship between these factors in collegiate RU players. Intrinsic and extrinsic factors included: age, weight, height, position of play (POP), previous SRCs, previous neck injuries; […]
Electroencephalographic findings and 5-year risk of posttraumatic epilepsy after mild traumatic brain injury: Insights from Second Karabakh War veterans
OBJECTIVE: This study aimed to investigate the long-term risk of posttraumatic epilepsy (PTE) and psychogenic nonepileptic seizures (PNES) following mild traumatic brain injury (mTBI) in combat veterans and to evaluate the predictive value of early electroencephalographic (EEG) abnormalities and the impact of trauma mechanism (blast vs. nonblast).
An Exploratory Analysis and Comparison of Post-Concussion Symptom Networks in Young Adults with and without a Remote History of Concussion
CONCLUSIONS: The variability in symptom presentations demonstrates the utility of within-person network models to match individuals to rehabilitation plans that best reflect their ongoing symptom experience over time. Future research should replicate this statistical approach in acutely injured, treatment-seeking individuals following concussion to determine if patterns of sleep impairments are truly specific to post-concussion presentations.
Validation of embedded PCL-5 symptom validity indices in active-duty military population
CONCLUSION: These findings provide support for the cross-validation of all three embedded symptom validity indices at the identified cutoff scores as PCL-5 over-report measures within an active-duty sample. The PSS and PES demonstrated superior classification statistics, as the PRI was hampered by lower sensitivity.
Depressive Symptoms in Concussed Youth Athletes: Factor Analysis of the Patient Health Questionnaire Modified for Adolescents (PHQ-A)
The presentation of depression symptoms in concussed youth athletes is not well understood. We examined the PHQ-A factor structure in concussed youth athletes. Five hundred and ninety-five youth athletes completed the PHQ-A and PCSS within 30 days of sport-related concussion. Factor analyses of the PHQ-A alone revealed a two-factor structure: cognitive-energy/sleep and emotional symptoms. When […]