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  • Traumatic brain injury

    Understanding White Matter Deformation: Insights into Brain Mechanics and Injury Prevention

    by Ioannis Mavroudis April 23, 2025
    by Ioannis Mavroudis April 23, 2025

    Introduction Traumatic brain injury (TBI) remains a significant public health concern, affecting millions globally each …

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  • Cognitive impairmentTraumatic brain injury

    Cognition After Traumatic Brain Injury: Rethinking Recovery, Complexity, and Hope

    by Ioannis Mavroudis April 13, 2025
    by Ioannis Mavroudis April 13, 2025

    Today, we’re delving into a topic that touches millions of lives but is still too …

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  • Diagnostic CriteriaTraumatic brain injury

    A Comparative Analysis of the ACRM Diagnostic Criteria and Mayo Classification System for Traumatic Brain Injury: Strengths, Limitations, and Clinical Accuracy

    by Ioannis Mavroudis March 14, 2025
    by Ioannis Mavroudis March 14, 2025

    Introduction Traumatic brain injuries (TBIs) remain a significant public health challenge, affecting millions worldwide each …

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  • Traumatic brain injury

    The Role of Magnetoencephalography in Diagnosing Concussion and Post-Concussion Syndrome: Clinical Applications and Legal Considerations

    by Ioannis Mavroudis February 4, 2025
    by Ioannis Mavroudis February 4, 2025

    Abstract Concussions and post-concussion syndrome (PCS) present diagnostic challenges due to their often subtle and …

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  • Traumatic brain injuryUncategorized

    Traumatic Brain Injury and the Risk of Dementia: Forensic Implications

    by Ioannis Mavroudis November 20, 2024
    by Ioannis Mavroudis November 20, 2024

    Traumatic Brain Injury (TBI) is a leading cause of neurological disability worldwide, with potential long-term …

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  • BiomarkersTraumatic brain injury

    Exploring the Role of Salivary Biomarkers in Mild Traumatic Brain Injury Diagnosis

    by Ioannis Mavroudis November 16, 2024
    by Ioannis Mavroudis November 16, 2024

    Abstract: Mild Traumatic Brain Injury (mTBI) is a significant public health concern, with its diagnosis …

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  • Chronic Traumatic EncephalopathyTraumatic brain injury

    Exploring the Complex Impact of Repeated Head Trauma in Contact Sports: Beyond CTE

    by Ioannis Mavroudis November 6, 2024
    by Ioannis Mavroudis November 6, 2024

    The connection between repeated head trauma and long-term health issues has gained significant attention in …

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  • Traumatic brain injury

    Charles Bonnet Syndrome (CBS) and Its Relationship with Concussion

    by Ioannis Mavroudis November 6, 2024
    by Ioannis Mavroudis November 6, 2024

    Charles Bonnet Syndrome (CBS) is a condition where individuals with significant vision loss experience visual …

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  • ResearchTraumatic brain injury

    The Impact of Tau Pathology in Chronic Traumatic Encephalopathy: Key Insights into Cognitive, Functional, and Neuropsychiatric Decline

    by Ioannis Mavroudis October 1, 2024
    by Ioannis Mavroudis October 1, 2024

    Recent research has shown significant connections between chronic traumatic encephalopathy (CTE) pathology and a variety …

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  • Traumatic brain injury

    The Role of the IMPACT Test in Concussion Screening and Treatment Planning

    by Ioannis Mavroudis September 28, 2024
    by Ioannis Mavroudis September 28, 2024

    Mild Traumatic Brain Injury (mTBI), commonly referred to as a concussion, has been a growing …

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  • Long-term neurological and psychiatric complications and vocational outcome after cerebral venous sinus thrombosis
    Patient Characteristics The demographic profile of patients who experience cerebral venous sinus thrombosis (CVST) provides…
  • Reply to “Clarifying the Moderating Role of Socioeconomic Status on Amyloid-Related Gray Matter Atrophy”
    Study Overview This study addresses the complex interactions between socioeconomic status (SES) and the neurobiological…
  • A Scoping Review of Measures Used to Assess Stress-Related Motor Dysfunction in Functional Movement Disorder
    Assessment Methods Overview Assessing stress-related motor dysfunction in individuals with functional movement disorder (FMD) encompasses…
  • Hysterical disorders in patients with hematological diseases
    Prevalence of Hysterical Disorders in Hematological Patients The intersection of hematological diseases and hysterical disorders…
  • Indigenizing paediatric concussion injury prevention
    Indigenous Perspectives on Concussion Understanding concussion within Indigenous communities requires a deep appreciation of cultural…

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Research

  • Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients
    CONCLUSIONS: S100B and the GFAP/UCH-L1 combination demonstrated very high sensitivities, close to 100 %, with specificities of approximately 30 % for the diagnosis of intracranial lesions. Age-adjusted thresholds improve specificity in older patients, supporting their clinical implementation. This study also provides the first evidence that hemolysis significantly elevates UCH-L1 concentrations from 400 mg/L of hemoglobin.
  • Retired contact sports athletes with cognitive concerns: promoting lifelong brain health
    There is widespread concern among former athletes about the link between head injury and dementia. Neurologists are increasingly assessing ex-contact sports athletes with cognitive and behavioural issues following repetitive head impacts and traumatic brain injury. Their assessment and management can be challenging due to the broad differential diagnosis, including psychiatric issues, trauma-related impairment and, in […]
  • Visible signs of possible concussion at the FIFA World Cup Qatar 2022: Independent review and inter-rater reliability
    CONCLUSIONS: Visible signs of concussion categorized as "red flags" were infrequent, resulting in uncertain reliability. The frequency and reliability of visible signs categorized as "yellow flags" and "other signs" varied, with the visible signs "clutching of the head" and "slow to get up" occurring so frequently that their utility for identifying possible concussion in football […]
  • Non-immersive virtual reality for cognitive rehabilitation of individuals with severe acquired brain injury (VR-sABI): study protocol for a multicentric randomized controlled trial
    BACKGROUND: After a severe acquired brain injury (sABI), individuals might experience mild-to-severe cognitive impairments. In these patients, cognitive rehabilitation is provided as early as possible, to take advantage of and guide brain plasticity. According to a restorative approach, traditional cognitive training (TCT) usually involves repeated paper-and-pencil exercises of increasing difficulty and targeting specific cognitive domains. […]
  • What traditional neuropsychological assessment got wrong about mild traumatic brain injury. III: the added value of advanced neuroimaging
    CONCLUSIONS: Characterizations from traditional neuropsychological measures as independent tests indicating no lasting sequelae from mTBI, especially after three-months post-injury from mTBI need to be viewed within the context of what advanced neuroimaging can demonstrate. Future directions involving the integration of advanced neuroimaging developments applicable to the mTBI patient are reviewed, especially when integrated with neuropsychological […]

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