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molecular pathology

Medical professionals Traumatic brain injury
Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

by Ioannis Mavroudis March 22, 2024

by Ioannis Mavroudis March 22, 2024

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies

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Educators' Perspectives of the Feasibility, Acceptability, and Appropriateness of the Buddy Program for Secondary School Students Post-Concussion
CONCLUSIONS: The Buddy Program aligns with school values and may be an avenue to support students returning to school following a concussion.
CTE neuropathology alone is associated with dementia and cognitive symptoms
INTRODUCTION: This studyexamined the independent contribution of chronic traumatic encephalopathy (CTE) neuropathology to symptoms.
Biomarker role in assessing imaging needs for mild cranial trauma (BRAIN-CT): study protocol for a single-center, randomized controlled trial
INTRODUCTION: Mild traumatic brain injury (mTBI) accounts for a significant proportion of emergency department (ED) visits, but current diagnostic protocols often lead to overuse of computed tomography (CT) imaging, despite low diagnostic yield. The BRAIN-CT trial evaluates the impact of rapid access to TBI biomarkers on decision-making for cranial imaging in patients with mTBI.
Spinal Cord Tau and Protein Copathologies Associated With Chronic Traumatic Encephalopathy
CONCLUSIONS AND RELEVANCE: This case-control study provides autopsy evidence of a high prevalence of complex spinal pathology in individuals with CTE-NC, supporting the concept of trauma-related encephalomyelopathy. The frequent co-occurrence of p-TDP-43, Aβ, and α-synuclein pathologies in individuals aged 65 years or older with CTE-NC suggests that cumulative trauma might contribute to widespread misfolded protein […]
Reactive Balance Deficits Differ in People After Mild Traumatic Brain Injury Based on Chronicity of Self-Reported Symptoms
CONCLUSIONS: Reactive balance deficits persist chronically after mTBI and differ between people with acute, sub-acute, and chronic symptoms. These differences suggest people with chronic symptoms may prioritize different aspects of balance control compared to the people in the acute stage of recovery related to functional adaptations to self-reported symptoms.

molecular pathology

Unlocking the Molecular Secrets of Traumatic Brain Injury: A Path Toward Innovative Diagnostics and Therapies