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movement disorders

Movement Disorders
Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Research Objectives The primary aim of this study is to explore the relationship between fluctuations …

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Functional neurological disorders
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Mechanisms of DG9 Action DG9 has emerged as a pivotal compound in the realm of …

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Movement Disorders
Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial)

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Study Overview The study aimed to investigate the safety and tolerability of intravenous liposomal GM1 …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Movement Disorders
A Rare Case of Bilateral Xanthomatosis of Tendon of Achilles: A Case Report

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Background of Bilateral Xanthomatosis Bilateral xanthomatosis is a rare condition characterized by the accumulation of …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) and its …

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Functional neurological disorders
Handwriting, touchscreen dexterity and bradykinesia measures in Parkinson’s disease: a feature selection study

by myneuronews May 11, 2025

by myneuronews May 11, 2025

Background on Parkinson’s Disease and Motor Symptoms Parkinson’s disease is a progressive neurodegenerative disorder primarily …

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Movement Disorders
The prodromal individuals’ perspective on active recruitment for early detection of α-synucleinopathies

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Perspective of Prodromal Individuals The perspective of individuals in the prodromal stage of α-synucleinopathies sheds …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Background and Rationale The treatment and study of Parkinson’s disease (PD) continue to evolve, particularly …

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Psychiatric outcomes after mild concussion by treatment timing and age
Previous guidance for mild concussion treatment has recommended physical and cognitive rest. However, it remains unknown if patients who received treatment at different times had differential neuropsychiatric outcomes. We examined if patients who received immediate treatment less than one week after a mild concussion had a different risk for subsequent depression or anxiety compared with […]
Modelling and Standardisation of EHR Data for Mild Traumatic Brain Injury Patient Management
In Spain, traumatic brain injury (TBI) affects 200 new cases per 100,000 inhabitants, making it a significant cause of morbidity and mortality globally and a frequent reason for emergency department attention. This study addresses the lack of consensus on the use of diagnostic tests to exclude intracranial lesions, leading to overuse of Computed Tomography (CT) […]
Brain activity dynamics after traumatic brain injury indicate increased state transition energy and preference of lower order states
Traumatic Brain Injury (TBI) can cause structural damage to the neural tissue and white matter connections in the brain, disrupting its functional coactivation patterns. Although there are a wealth of studies investigating TBI-related changes in the brain's structural and functional connectomes, fewer studies have investigated TBI-related changes to the brain's dynamic landscape. Network control theory […]
Averaged 22-month test-retest reliability of non-computerized baseline cognitive assessments in healthy youth athletes
CONCLUSIONS: All measures, except NEPSY-II Memory for Designs, demonstrated moderate to good test-retest reliability for both absolute and normed scores over an average 22-month interval between baseline administrations. However, clinicians should not overlook potential practice effects when interpreting a youth athlete's second baseline performance. The authors also underscore the value of examining raw data in […]
Laboratory Evaluation of a Wearable Instrumented Headband for Rotational Head Kinematics Measurement
CONCLUSION: This new instrumented headband improves upon previous headband designs in reconstructing the rotational head kinematics resulting from frontal soccer ball impacts, providing a potential alternative to instrumented mouthguards.