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movement disorders

Functional neurological disorders
Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Immune Mechanisms in Anti-NMDAR Encephalitis Anti-NMDAR encephalitis is characterized by the presence of antibodies that …

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Functional neurological disorders
Atypical cadherin FAT2 is required for synaptic integrity and motor behaviors

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Role of fat2 in Synaptic Integrity The study of the atypical cadherin FAT2 unveils its …

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Functional neurological disorders
Clinical Practice Updates: AGA Clinical Practice Update on GI Manifestations and Autonomic or Immune Dysfunction in Hypermobile Ehlers-Danlos Syndrome: Expert Review

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Clinical Considerations in Hypermobile Ehlers-Danlos Syndrome In examining Hypermobile Ehlers-Danlos Syndrome (hEDS), it’s essential to …

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Functional neurological disorders
Functional Movement Disorder: Evolving Mechanisms, Diagnostic Precision, and Personalized Multidisciplinary Care

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Functional Movement Disorder Functional Movement Disorder (FMD) encompasses a range of abnormal movement patterns …

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Functional neurological disorders
Loneliness in Parkinson’s disease: Subjective experience overshadows objective motor impairment

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Understanding Loneliness in Parkinson’s Disease Loneliness is a profound and complex emotion that frequently accompanies …

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Functional neurological disorders
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Mechanisms of DG9 Action DG9 has emerged as a pivotal compound in the realm of …

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Functional neurological disorders
Spatial Multiomics Toward Understanding Neurological Systems

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding Spatial Multiomics Spatial multiomics is revolutionizing our understanding of the brain and its complex …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) and its …

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Functional neurological disorders
Handwriting, touchscreen dexterity and bradykinesia measures in Parkinson’s disease: a feature selection study

by myneuronews May 11, 2025

by myneuronews May 11, 2025

Background on Parkinson’s Disease and Motor Symptoms Parkinson’s disease is a progressive neurodegenerative disorder primarily …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Autologous bone marrow mononuclear cell administration for neurological sequelae after traumatic brain injury: a matched control study
Neurological sequelae after traumatic brain injury impair motor and behavioural functions, imposing a heavy burden on patients and society. Traditional treatments show limited efficacy, highlighting the need for advanced therapies. This study evaluated the safety and efficacy of intrathecal administration of bone marrow mononuclear cells for treating these sequelae. A matched control clinical trial was […]
Concussion Classification in a Multicenter Patient Cohort: The Updated ACRM Diagnostic Criteria and Concordance With Physician Impression of Injury
CONCLUSION: Use of the ACRM criteria clinically to determine if an injury qualifies as mTBI may be less susceptible to bias from ongoing symptom reporting than the physician impression of the injury.
Immediate Postoperative Virtual Reality Therapy for Phantom Limb Pain in Multiextremity Amputees: A Report of 3 Cases
CONCLUSION: These cases demonstrate that VR can be safely and effectively implemented postoperatively following multiextremity amputation, suggesting potential for expanded use even in similarly complex cases.
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients
CONCLUSIONS: S100B and the GFAP/UCH-L1 combination demonstrated very high sensitivities, close to 100 %, with specificities of approximately 30 % for the diagnosis of intracranial lesions. Age-adjusted thresholds improve specificity in older patients, supporting their clinical implementation. This study also provides the first evidence that hemolysis significantly elevates UCH-L1 concentrations from 400 mg/L of hemoglobin.
Retired contact sports athletes with cognitive concerns: promoting lifelong brain health
There is widespread concern among former athletes about the link between head injury and dementia. Neurologists are increasingly assessing ex-contact sports athletes with cognitive and behavioural issues following repetitive head impacts and traumatic brain injury. Their assessment and management can be challenging due to the broad differential diagnosis, including psychiatric issues, trauma-related impairment and, in […]