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movement disorders

Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Electrophysiological Properties of hiPSC-Derived Neurons The study begins by examining the electrophysiological properties of human-induced …

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Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Background and Rationale The treatment and study of Parkinson’s disease (PD) continue to evolve, particularly …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Factors in Parkinson’s Disease Parkinson’s Disease (PD) is a multifactorial neurological disorder, with both …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Landscape of Parkinson’s Disease in India Parkinson’s Disease (PD) presents a complex interplay of …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Factors Influencing Parkinson’s Disease Parkinson’s Disease (PD) is a progressive neurodegenerative disorder primarily characterized …

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Functional neurological disorders
Will adaptive deep brain stimulation for Parkinson’s disease become a real option soon? A Delphi consensus study

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Adaptive Deep Brain Stimulation Approaches Adaptive deep brain stimulation (aDBS) represents a significant evolution in …

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Functional neurological disorders
Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Clinical Effectiveness of Thalamotomy Bilateral focused ultrasound thalamotomy (FUS thalamotomy) has emerged as a promising …

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Functional neurological disorders
Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Clinical Efficacy of Thalamotomy The use of bilateral focused ultrasound thalamotomy (FUS) represents a significant …

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Functional neurological disorders
Photoacoustic technologies in nervous system disorders: an emerging strategy for neuromodulation

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Emerging Applications of Photoacoustic Technologies Photoacoustic technologies have been gaining traction in recent years as …

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Functional neurological disorders
Neurocomputational Mechanisms of Sense of Agency: Literature Review for Integrating Predictive Coding and Adaptive Control in Human-Machine Interfaces

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Neurocomputational Framework The neurocomputational framework offers a compelling way to understand how the brain processes …

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Shape analysis of the amygdala, hippocampus and thalamus in former American football players
Repetitive head impacts are common in contact and collision sports and are linked to structural brain changes and an elevated risk of neurodegenerative diseases such as Chronic Traumatic Encephalopathy. Identifying early in vivo structural markers remains challenging. Although diagnosis currently requires post-mortem confirmation, clinical symptoms, including cognitive impairment and behavioural changes, are reflected in the […]
TDP-43 dysfunction leads to impaired proteostasis and predisposes mice to worse neurological outcomes after brain injury
CONCLUSIONS: Our data demonstrate that expression of dysfunctional TDP-43 leads to deficits within the proteostasis network in vivo at baseline. Despite an upregulation of proteostasis-related genes at the transcript level in mutant TDP-43 mice after TBI, mutant TDP-43 mice exhibit an impaired response to, and recovery from, brain trauma relative to their WT counterparts. Restoring […]
Depression-like behavior following mild traumatic brain injury in adolescent rats: a role for limbic neuropeptides
Mild traumatic brain injury (mTBI) is common among adolescents because of their participation in contact sports and mTBI is more likely to lead to depression-related behaviors in girls than boys. Various neuropeptides, often within the limbic system, have been implicated in the regulation of depression-related behaviors. To identify potential neuropeptide involvement in behavioral effects of […]
Resting-state EEG and machine learning to investigate cortical connectivity as a biomarker in chronic mTBI
Mild traumatic brain injury (mTBI) is a heterogeneous condition with long-term sequelae, yet diagnosis in the chronic stage remains limited by reliance on acute criteria and subjective reports. Objective biomarkers are needed, as current blood-based markers show diagnostic value primarily in the acute and subacute phases. Resting-state EEG (RS-EEG) can capture large-scale network disruptions through […]
Pre- and Post-treatment Impact of Antioxidants on Astrocytic Reactive Oxygen SpeciesAn Undergraduate Classroom Research Project
Undergraduate research is a method to enhance student engagement in science courses as well as expand scientific curiosity. One method in doing so is performing course undergraduate research experiences. This project started as an undergraduate research project and expanded into a six-week in-class honor's research experience. The field of traumatic brain injury (TBI) evokes instant […]