Tag:

mTBI

Traumatic brain injury
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H(2)S-dependent S-sulfhydration of CTSD

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Study Overview The research focuses on the role of Snapin, a protein that contributes to …

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Traumatic brain injury
Concussion recovery time, return-to-play protocols, and mandated sit-out periods among adult amateur contact field sports: A systematic review

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Concussion Recovery Insights Concussion recovery is influenced by a variety of factors, including the severity …

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Traumatic brain injury
Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Creatine’s Role in Brain Health Creatine, a compound predominantly recognized for its benefits in muscle …

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Traumatic brain injury
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial

by myneuronews January 20, 2026

by myneuronews January 20, 2026

Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of …

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Traumatic brain injury
Corrigendum to ‘Anti-Inflammatory, Antioxidant and Neuroprotective Effects of Niacin on Mild Traumatic Brain Injury in Rats.’

by myneuronews January 19, 2026

by myneuronews January 19, 2026

Study Overview The investigation was centered around evaluating the therapeutic contributions of niacin, a form …

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Traumatic brain injury
Loss of Fatty Acid Oxidation by Neural Stem and Progenitor Cells Increases Proliferation but Does Not Improve Long-Term Neurogenesis After Mild Traumatic Brain Injury

by myneuronews January 19, 2026

by myneuronews January 19, 2026

Fatty Acid Oxidation and Neural Stem Cells Fatty acid oxidation plays a critical role in …

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Traumatic brain injury
CT Brain Utilization After Low-Risk Head Injury in Adults: A Retrospective Cohort Study and Literature Review

by myneuronews January 19, 2026

by myneuronews January 19, 2026

Study Overview This analysis examines the patterns of computed tomography (CT) brain utilization in patients …

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Traumatic brain injury
A multicenter, international, randomized, single-blind, placebo-controlled study of the efficacy and safety of inosine-nicotinamide-riboflavin-succinic acid in the acute period of traumatic brain injury in adults

by myneuronews January 19, 2026

by myneuronews January 19, 2026

Study Overview This investigation is a multicenter, international trial designed to evaluate the effectiveness and …

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Traumatic brain injury
Prevalence of post-traumatic hypopituitarism in active-duty service members receiving comprehensive care for traumatic brain injury (TBI) and psychological health: A military mild TBI cohort study

by myneuronews January 19, 2026

by myneuronews January 19, 2026

Study Overview This research investigates the occurrence of post-traumatic hypopituitarism among active-duty military personnel who …

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Traumatic brain injury
A Novel NLRP3 Inhibitor AMS-17 Rescues Deficits in Long-Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice

by myneuronews January 18, 2026

by myneuronews January 18, 2026

Study Overview The research focuses on investigating the effects of a novel NLRP3 inhibitor, AMS-17, …

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Brain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia
Prognostic Value of EV Proteome in Schizophrenia The examination of extracellular vesicles (EVs) in schizophrenia…
Are symptoms clustered into latent classes in pediatric functional neurological disorder?
Symptoms Clustering in Pediatric Functional Neurological Disorder Pediatric functional neurological disorder (FND) presents a complex…
An e-Delphi approach to develop a patient-reported outcome measure to assess functional/dissociative seizures severity
Study Overview In recent years, the growing recognition of the impact of functional/dissociative seizures on…
Diagnostic challenges in Burkitt’s lymphoma with skull base and paravertebral involvement, and hearing loss: a case report
Study Overview This case report focuses on Burkitt’s lymphoma, a highly aggressive type of non-Hodgkin…
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
Study Overview The research aimed to investigate the role of miR-26b-5p in the recovery of…

Leveraging the Enhanced Sports as a Laboratory Assessment Model to Cross-Validate a Formula Used to Predict Clinical Recovery From Concussion in Collegiate Athletes
CONCLUSIONS: Upon cross-validation, our prognostic formula had limited sensitivity and specificity when predicting clinical recovery after concussion. This formula may be used, with caution, when accompanied by a multidimensional assessment to inform clinical decision making after concussion.
miR-26b-5p responds to aerobic exercise intervention for concussion recovery in adolescent athletes: a pilot trial
CONCLUSION: miRNAs 1246, 944, and 151a-3p may be concussion biomarkers unaffected by aerobic exercise. miR-26b-5p, associated with concussion and exercise volume, may be a useful biomarker to monitor adherence to exercise prescriptions for SRC recovery.
Creatine Supplementation and the Brain: Have We Put the Cart Before the Horse?
Creatine is an important regulator of brain bioenergetics, yet the efficacy of creatine supplementation (CrS) in the brain remains largely unknown. Measurement of brain creatine using proton (¹H) and phosphorus (³¹P) magnetic resonance spectroscopy is highly sensitive to voxel placement, signal quality, analysis pipelines, and reporting conventions which can obscure the detection of biological responses […]
Concussion recovery time, return-to-play protocols, and mandated sit-out periods among adult amateur contact field sports: A systematic review
CONCLUSION: Recovery time following concussion in contact sports should be interpreted in light of sport type, mandated sit-out policies, and RTP protocols. Empirical evidence should drive decisions in RTP protocols and sit-out periods, which are currently inconsistent between sports.
Snapin mediates neuronal PANoptosis after mild traumatic brain injury via H(2)S-dependent S-sulfhydration of CTSD
CONCLUSION: Snapin promotes mTBI-induced neuronal PANoptosis by disrupting the H(2)S/CTSD pathway through specific binding with CBS. Therapeutic strategies targeting Snapin, restoring H(2)S homeostasis, or inhibiting CTSD activation may significantly alleviate neurological impairment and neuroinflammation post-mTBI, highlighting novel therapeutic avenues for mTBI treatment.