Tag:

neurodegenerative diseases

Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Traumatic brain injury
Biomarker evidence of neurodegeneration in mid-life former rugby players

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurodegeneration Biomarkers Biomarkers indicative of neurodegeneration are crucial for understanding the underlying processes affecting brain …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Traumatic brain injury
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Study Overview This study investigates the effects of mild repetitive head injuries on brain function …

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Traumatic brain injury
Pediatric Mild Traumatic Brain Injury and Concussion

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Understanding Mild Traumatic Brain Injury in Pediatric Patients Pediatric mild traumatic brain injury (mTBI), commonly …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research investigates the impact of cannabidiol (CBD) on rats subjected to multiple …

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Functional neurological disorders
Myeloproliferative syndrome as a cause of chorea

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Myeloproliferative Syndrome Overview Myeloproliferative syndromes (MPS) are a group of blood disorders characterized by the …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Relevance of Biomarkers The study underscores the pivotal role of biomarkers in the clinical …

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Traumatic brain injury
Postmortem tau in the CA2 region of the hippocampus in older adult men who participated in youth amateur American-style football

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview The research focuses on examining the accumulation of tau protein in the CA2 …

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Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium
CONCLUSIONS: These findings collectively identify COL4A1 deficiency as a sensitizing factor for post-traumatic visual dysfunction and demonstrate that ASC-CCM exerts therapeutic effects by preserving retinal vascular structure and modulating inflammatory responses, positioning it as a promising candidate for treating TBI-related ocular neurovascular injury.
Hollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury
Traumatic brain injury (TBI) remains a significant global health burden and demands rapid, objective diagnostics that work outside imaging suites and intensive lab workflows. Here, we developed a copper sulfide (CuS) nanocube-assisted laser desorption/ionization mass spectrometry (LDI-MS) platform to acquire serum metabolic profiles (SMPs) with high sensitivity, low background in the low-m/z region, and excellent […]
Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study
Introduction This study examines whether attention-deficit/hyperactivity disorder (ADHD) can develop after traumatic brain injury in children. Overlapping acute symptoms can hinder early identification and diagnosis. We investigated whether demographic or acute clinical features are associated with the development of secondary ADHD (S-ADHD) following mild pediatric traumatic brain injury. Materials and methods We conducted a retrospective […]
Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint
Transcranial direct current stimulation (tDCS) for painless, non-invasive brain stimulation is a promising approach to enhance recovery after stroke. However, the precise molecular and cellular mechanisms underlying the effects of tDCS remain unclear, impeding its use in humans and necessitating research in experimental animals. Unlike humans, who receive tDCS fully awake, experimental models of tDCS […]
Artificial Intelligence in Traumatic Brain Injury: A Systematic Review of Prognostic, Diagnostic, and Monitoring Applications
Traumatic brain injury (TBI) remains a leading cause of death and disability worldwide, with outcomes that are highly heterogeneous and difficult to predict using conventional clinical tools. Artificial intelligence (AI) has emerged as a promising approach to enhance diagnosis, prognostication, and management of TBI across diverse care settings. Following PRISMA guidelines, a comprehensive search of […]