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neurodegenerative diseases

Functional neurological disorders
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Microglia Replacement Strategy The study introduces an innovative approach to addressing neurological disorders through the …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Regulation of chronic neuroinflammation through dietary herbal products

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Role of Dietary Herbal Products in Neuroinflammation Dietary herbal products have garnered significant interest in …

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Dementia
FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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Functional neurological disorders
Frontotemporal dementia: a systematic review of artificial intelligence approaches in differential diagnosis

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Overview of Frontotemporal Dementia Frontotemporal dementia (FTD) is a complex neurodegenerative disorder that primarily affects …

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Functional neurological disorders
Gut Neuropeptide Involvement in Parkinson’s Disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Gut Neuropeptides and Their Role in Neurodegeneration Gut neuropeptides are crucial biochemical messengers that play …

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Functional neurological disorders
Chemical imaging delineates Aβ plaque polymorphism across the Alzheimer’s disease spectrum

by myneuronews April 24, 2025

by myneuronews April 24, 2025

Aβ Plaque Polymorphism Overview Amyloid-beta (Aβ) plaques are characteristic features found in the brains of …

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Medical professionals Traumatic brain injury
Brain Pathology in the Context of Concussion History

by Ioannis Mavroudis March 1, 2024

by Ioannis Mavroudis March 1, 2024

Exploring the intricate relationship between concussion history and brain pathology reveals a complex interplay of …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Pediatric concussion characteristics differ based on age
CONCLUSIONS: The results build on previous studies showing that younger pediatric patients sustain concussions mostly from non-sports mechanisms and endorse fewer symptoms which could be due to lower severity of injury and/or primarily relying on parent reporting of observable concussion symptoms. Pediatric concussion mechanism and presentation differ across ages, emphasizing the importance of age-appropriate symptom […]
Glymphatic system and mild traumatic brain injury: a mini review
Since the discovery of the glymphatic system in 2012, research on this brain-wide fluid exchange pathway has focused on understanding its role in different neurological diseases. Mild traumatic brain injury (mTBI) is a prevalent, yet often undiagnosed, condition that increases the risk of developing debilitating neurodegenerative diseases. mTBI may lead to impaired glymphatic system function […]
Subtle ocular motor deficits in people with chronic whiplash associated disorder compared to healthy controls
INTRODUCTION: More than 50% of people who are diagnosed with whiplash-associated disorder (WAD) will report symptoms 12 months and beyond after their initial onset. However, many signs and symptoms, such as dizziness, emotional lability, confusion, ocular movement abnormalities, and balance deficits, may not be directly attributed to the cervical spine and may be more consistent […]
Symptom burden in the first four years following hospitalization after mild traumatic brain injury
CONCLUSIONS: Clinicians should be alert to the long-term presence of multiple symptoms following hospitalization after mTBI, as these affect a significant proportion of individuals and are associated with poorer outcomes.
Neither American Football Playing Position Nor Total Years Playing Football Are Associated with Neurobehavioral Health Outcomes: An NFL-LONG Study
Years playing American football and primary playing position are often used to estimate concussion exposure. We examined associations between playing position and total years played with concussion history and neurobehavioral outcomes among former (N = 1544) National Football League players in the NFL-LONG study. Outcomes included the PROMIS Cognitive, Depression, and Anxiety T-scores, and Neuro-QOL […]