Tag:

neurodegenerative diseases

Dementia
Differential microglial responses to structurally distinct alpha-synuclein polymorphs

by myneuronews December 6, 2025

by myneuronews December 6, 2025

Differential Responses of Microglia Microglia, the resident immune cells of the central nervous system, exhibit …

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Traumatic brain injury
Mechanisms of naozhenning in inhibiting neuronal ferroptosis and alleviating brain recurrent mild traumatic brain injury in a rat model

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Mechanisms of Ferroptosis Inhibition Ferroptosis is a distinct form of regulated cell death characterized by …

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Functional neurological disorders
Psychiatric presentation of Gerstmann-Sträussler-Scheinker disease with 9-OPRI mutation in PRNP gene: a case report

by myneuronews December 2, 2025

by myneuronews December 2, 2025

Clinical Presentation The patient presented in this case report exhibited a variety of psychiatric symptoms …

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Functional neurological disorders
Psychiatric presentation of Gerstmann-Sträussler-Scheinker disease with 9-OPRI mutation in PRNP gene: a case report

by myneuronews December 2, 2025

by myneuronews December 2, 2025

Case Overview In this study, we explore the case of a patient diagnosed with Gerstmann-Sträussler-Scheinker …

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Functional neurological disorders
Psychiatric presentation of Gerstmann-Sträussler-Scheinker disease with 9-OPRI mutation in PRNP gene: a case report

by myneuronews December 2, 2025

by myneuronews December 2, 2025

Clinical Features of Gerstmann-Sträussler-Scheinker Disease Gerstmann-Sträussler-Scheinker disease (GSS) is a rare genetic disorder that predominantly …

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Functional neurological disorders
Psychiatric presentation of Gerstmann-Sträussler-Scheinker disease with 9-OPRI mutation in PRNP gene: a case report

by myneuronews December 2, 2025

by myneuronews December 2, 2025

Clinical Presentation and Symptoms Gerstmann-Sträussler-Scheinker disease (GSS) is a rare neurodegenerative disorder classified as a …

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Functional neurological disorders
Psychiatric presentation of Gerstmann-Sträussler-Scheinker disease with 9-OPRI mutation in PRNP gene: a case report

by myneuronews December 2, 2025

by myneuronews December 2, 2025

Clinical Presentation The case under discussion presents a unique manifestation of Gerstmann-Sträussler-Scheinker (GSS) disease, particularly …

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Traumatic brain injury
Concussion recovery: dual task performance and prioritization

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Concussion Mechanisms Concussions result from a variety of forces acting on the brain, primarily due …

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Traumatic brain injury
Worrying about Concussions and Brain Health is Strongly Associated with Psychological Distress in Former Elite Rugby League Players

by myneuronews December 1, 2025

by myneuronews December 1, 2025

Worrying About Concussions Concerns regarding concussions have become increasingly prevalent, particularly among athletes in contact …

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Dementia
Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson’s disease and Lewy Body Dementia cohorts

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Study Overview This research investigates the presence and significance of expanded and interrupted repeat expansions …

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Platforms to Evaluate Flavivirus-Induced Immunoinflammatory Responses and Their Pathogenesis
Overview of Flavivirus Pathogenesis Flaviviruses, a diverse group of RNA viruses, are known to cause…
Comparative Assessment of Mental and Cognitive Status
Assessment Framework The evaluation of mental and cognitive status relies on a structured framework that…
How Developing Brains Differ: Pediatric Functional Neurological Disorder: Distinct Clinical Courses, Unique Needs, Personalized Communication, and Pathways to Recovery
Understanding Pediatric Functional Neurological Disorder Pediatric Functional Neurological Disorder (pFND) refers to a condition where…
Somatic symptom and related disorders in the Arab world: a narrative review of clinical features and care implications
Clinical Features of Somatic Symptom Disorders Somatic symptom disorders encompass a diverse range of clinical…
Reclaiming Functional Neurological Disorder for Rehabilitation Medicine
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) is a complex condition characterized by neurological…

Enhancing Outpatient Clinic Recruitment: A Quality Improvement Strategy for a Prospective Research Study
CONCLUSIONS: This project demonstrates the successful application of quality improvement methodology toward optimizing clinical recruitment. Approaches used in this study can potentially be generalized to other outpatient clinical populations and research studies.
Driving After Concussion: Clinical Measures Associated With Postconcussion Driving
CONCLUSIONS: Dual-task and Complex Figure tests might be useful when assessing postconcussion driving ability. Higher VOMS symptom provocation was associated with better driving performance, possibly indicating that individuals experiencing vestibular-oculomotor symptoms may adopt more cautious strategies.
Health Literacy Among Adolescent Athletes Across Rural and Urban Communities and Evaluating Scores Aside State-Mandated Concussion Education
CONCLUSIONS: Urban adolescent athletes had better health literacy compared with their rural peers; however, irrespective of rurality, more than half of participants had low health literacy for their appropriate age/grade in high school (≤seventh grade). Ensuring that health information is provided at an appropriate reading level for the target audience is essential to increasing health […]
Effectiveness of intensive exposure therapy for persistent post-concussion symptoms: an aggregated single-case design approach
The fear-avoidance model suggests that catastrophising and avoidance behaviours can maintain persistent post-concussion symptoms (PPCS) after mild traumatic brain injury (mTBI). Although exposure therapy has shown preliminary success in this population, its effectiveness in mTBI remains unproven. This study investigated the therapeutic effects of this therapy across different settings. Twenty participants with PPCS took part […]
Plasma biomarkers in chronic mild traumatic brain injury: A review
Background/Objective: Understanding the biological cascade which results from a mild traumatic brain injury (mTBI) is essential to determine outcomes over time. Acute plasma levels of brain-related injury markers (BRIMS; ubiquitin carboxy-terminal hydrolase L1 [UCH-L1], total tau[t-tau], neurofilament light chain [NfL], S100 calcium-binding protein β [S100β], glial fibrillary acidic protein [GFAP]) are typically elevated in patients […]