Tag:

neurodegenerative diseases

Functional neurological disorders
Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Background and Rationale The treatment and study of Parkinson’s disease (PD) continue to evolve, particularly …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Background and Rationale The study of genetic factors influencing neurological conditions has gained momentum in …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Overview of RBD and α-Synucleinopathies As research into neurodegenerative disorders continues to evolve, it becomes …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to predict the …

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Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Landscape of Parkinson’s Disease in India Parkinson’s Disease (PD) presents a complex interplay of …

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Functional neurological disorders
Clinical and Neuropathological Evaluations of the New Brunswick Neurological Syndrome of Unknown Cause

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Clinical Presentation and Symptoms In examining the New Brunswick Neurological Syndrome of Unknown Cause (NBNSUC), …

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Stroke
Exosome-powered neuropharmaceutics: unlocking the blood-brain barrier for next-gen therapies

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Exosome Technology in Neuropharmaceutics Exosomes represent a groundbreaking advancement in the field of neuropharmaceutics, offering …

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Traumatic brain injury
Diffusion Tensor Image Analysis Along the Perivascular Space in Former Professional Athletes with Repetitive Mild Traumatic Brain Injury History

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Study Overview This research focuses on the implications of repetitive mild traumatic brain injuries (mTBI) …

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Traumatic brain injury
Diffusion Tensor Image Analysis Along the Perivascular Space in Former Professional Athletes with Repetitive Mild Traumatic Brain Injury History

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Background and Rationale Understanding the implications of repetitive mild traumatic brain injuries (mTBIs) is essential, …

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Unsophisticated AI coaching does not improve performance on symptom and performance validity tests in a Romanian sample of experimental feigners
The present study aimed to investigate the ability of symptom and performance validity indicators to detect experimental feigning with symptom-coaching vs. AI assistance. Fifty-nine undergraduates and community members (45 females, M(Age)=22.6, SD(Age)=2.1; M(Education)=14.5, SD(Education)=1.4) were randomized into three experimental groups: controls (n = 20), symptom-coached feigners (n = 20), and AI-coached feigners (n = 19). […]
Factors affecting mortality risk in pediatric head injuries in Africa: a meta-analysis
CONCLUSION: Our study emphasizes RTA and seizures at presentation as key risk factors for mortality. We recommend early preventive measures, such as infrastructure improvements, to enhance road safety and reduce mortality.
Nonsteroid Anti-Inflammatory Drug Use in Female Elite Ice Hockey Players With and Without Previous Concussions and Musculoskeletal Injuries
Ice hockey is a high-intensity sport with high rates of concussions and musculoskeletal injuries. To manage pain, players may (over) use nonsteroid anti-inflammatory drugs (NSAIDs) which can have adverse health effects. In 2022, the Swedish Women's Elite League (SDHL) became the first women's league to introduce body checking, potentially increasing injury risks and NSAID use. […]
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice
The mammalian brainstem is particularly vulnerable to mild traumatic brain injury (mTBI), which is associated with prolonged autonomic dysfunction and coma. The spatial cellular connections within the brainstem or the mechanisms underlying its response to injury have been underestimated. Here, we performed single-nucleus RNA sequencing with spatial transcriptome sequencing in both normal and mTBI brainstems […]
Post-Concussion Changes in the Functional Brain Connectome Relative to Pre-Injury Baseline: A Prospective Observational Study
There is growing concern about the long-term health consequences of concussion, stemming from its high incidence and evidence of post-injury sequelae. This has raised critical questions about clinical assessments of concussion recovery, and whether brain function has fully recovered at medical clearance. The major knowledge gap is only partly addressed by conventional cross-sectional neuroimaging studies, […]