Tag:

neurodegenerative diseases

Functional neurological disorders
Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical changes in rapid eye movement sleep behavior disorder Recent studies have highlighted significant alterations …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy Recent research into alpha-synucleinopathy—disorders associated with the abnormal accumulation of the …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Traumatic brain injury
Biomarker evidence of neurodegeneration in mid-life former rugby players

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurodegeneration Biomarkers Biomarkers indicative of neurodegeneration are crucial for understanding the underlying processes affecting brain …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Traumatic brain injury
Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Study Overview This study investigates the effects of mild repetitive head injuries on brain function …

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Traumatic brain injury
Pediatric Mild Traumatic Brain Injury and Concussion

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Understanding Mild Traumatic Brain Injury in Pediatric Patients Pediatric mild traumatic brain injury (mTBI), commonly …

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Functional neurological disorders
Clinically Accurate Diagnosis of Alzheimer’s Disease via Single-Molecule Bioelectronic Label-Free Profiling of Multiple Blood Extracellular Vesicle Biomarkers

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Overview of Bioelectronic Profiling Techniques Bioelectronic profiling has emerged as a revolutionary approach for the …

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Traumatic brain injury
Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2alpha-ATF4-CHOP pathway

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The research investigates the impact of cannabidiol (CBD) on rats subjected to multiple …

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Functional neurological disorders
Myeloproliferative syndrome as a cause of chorea

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Myeloproliferative Syndrome Overview Myeloproliferative syndromes (MPS) are a group of blood disorders characterized by the …

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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that…
Collaborative Community Support for People Impacted by Dementia: A Social Return on Investment Analysis
Study Overview This research focuses on understanding the impact of a community-based support program designed…
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Cognitive Fatigue in Pediatric Populations Cognitive fatigue is a significant concern in pediatric populations, particularly…
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the…
ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Study Overview The study focuses on enhancing the accuracy of brain lesion parcellation, a crucial…

Substrate-selective COX-2 inhibition by IMMA attenuates posttraumatic headache via endocannabinoid modulation and neuroinflammatory suppression
CONCLUSION: IMMA effectively attenuates neuroinflammation and pain hypersensitivity in the acute phase of PTH through a distinct mechanism that preserves endocannabinoid tone without suppressing physiological prostaglandins. While these results highlight its promise as a novel therapeutic strategy, further studies are warranted to determine its efficacy during the chronic phase of PTH and across anatomically targeted […]
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Acquired Brain Injuries (ABIs) cause long-term disruption to young individuals' development. Persistent cognitive fatigue is a commonly reported sequela following pediatric ABI. Currently, there are no evidence-based interventions targeting cognitive fatigue post-ABI amongst pediatric patients. The current systematic review and meta-analysis aimed to review research on the efficacy of pharmacological and non-pharmacological interventions for cognitive […]
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
CONCLUSION: Serum TMAO levels were significantly elevated in PTSD patients comorbid with TBI and were closely associated with PTSD severity. Furthermore, TMAO may aid in the early identification of high-risk, severe PTSD patients following TBI, thus helping to optimize intervention strategies.
ENIGMA's advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Cortical parcellation is a critical step in several neuroimaging pipelines, yet even in high quality images without pathology, errors are common. For patients with moderate to severe traumatic brain injury (ms-TBI), typical parcellation errors can be exacerbated by focal pathology impacting cortical regions. Careful visual quality checking (QC) of parcellation images of ms-TBI patients should […]
Knowledge and attitudes of concussion and chronic traumatic encephalopathy amongst a sample of non-professional rugby players
CONCLUSIONS: Non-professional rugby players are generally knowledgeable about concussion. However, some gaps in their knowledge relating to coma and the course of symptoms of concussion were identified. Unsafe attitudes, particularly among school players, need to be addressed. Non-professional rugby players are interested in further education about CTE.