Tag:

neurodegenerative diseases

Dementia
Exploring the mediating role of the plasma lipidome in the pathway from the gut microbiota to dementia: a Mendelian randomization study

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Study Overview This research investigates the intricate relationships between gut microbiota, plasma lipid profiles, and …

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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Traumatic brain injury
A voice for Tom: an urgent call for more research into neurodegenerative disease and contact sport

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Neurodegenerative Disease and Contact Sports Neurodegenerative diseases represent a broad category of disorders characterized by …

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Traumatic brain injury
Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Historical Context of Neurological Disorders The understanding of neurological disorders in Boxers has evolved significantly …

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Traumatic brain injury
Cognitive-Communication Rehabilitation after Brain Injuries

by myneuronews July 28, 2025

by myneuronews July 28, 2025

Cognitive Communication Challenges Cognitive communication challenges arise when individuals experience difficulties in the processes that …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Functional neurological disorders
Integrated in silico identification of cholinesterase inhibitors from Nyctanthes arbor-tristis

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Identification of Cholinesterase Inhibitors Research has increasingly focused on the potential therapeutic roles of various …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Dementia
Cognitive Function, Physical Activity, and Sweat Cytokines in Older Adults With Dementia

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Cognitive Function Assessment Assessing cognitive function in older adults, especially those with dementia, involves various …

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Functional neurological disorders
Identifying individuals at-risk of developing Parkinson’s disease using a population-based recruitment strategy: The Healthy Brain Ageing Kassel Study

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Objectives and Rationale The study aimed to address a critical gap in our understanding …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Pediatric concussion characteristics differ based on age
CONCLUSIONS: The results build on previous studies showing that younger pediatric patients sustain concussions mostly from non-sports mechanisms and endorse fewer symptoms which could be due to lower severity of injury and/or primarily relying on parent reporting of observable concussion symptoms. Pediatric concussion mechanism and presentation differ across ages, emphasizing the importance of age-appropriate symptom […]
Mild traumatic brain injury and concussion and persisting post-concussion symptoms: new guidelines to support evidence-based assessment and management in Australia and Aotearoa New Zealand
No abstract
Examining Clinic-Based Healthcare Utilization Patterns in a Specialty Concussion Care Setting
CONCLUSIONS: Initiation of concussion care within one week of injury demonstrates comparable effectiveness regardless of exact timing, although early presentation favors single-provider management while later presentation requires enhanced interdisciplinary coordination.
Evaluating Diagnostic Strategies for Pediatric Traumatic Brain Injury: A Literature-Based Clinical Decision Analysis
CONCLUSIONS: Application of CDA to pediatric TBI demonstrates the potential value of biomarker integration in improving diagnostic accuracy and optimizing CT utilization. Biomarker-augmented strategies may enhance patient safety by reducing unnecessary radiation exposure, while maintaining sensitivity for clinically important injuries. Prospective validation and real-world implementation studies are needed to confirm clinical effectiveness and cost-effectiveness.
Isolated oculomotor nerve palsy following mild traumatic brain injury: diagnostic challenges and insights from High-Resolution MRI
CONCLUSIONS: High-resolution CE-MRI proves instrumental in diagnosing isolated ONP in mild TBI patients, even without conventional radiological indicators. Early imaging and intervention may improve recovery outcomes. This study underscores the significance of including CE-MRI in evaluation protocols for ONP. It highlights the importance of further research to unravel the underlying pathophysiology and optimize therapeutic approaches […]