Tag:

neurodegenerative diseases

Traumatic brain injury
Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients

by myneuronews October 8, 2025

by myneuronews October 8, 2025

Study Overview This study examined the efficacy of three biomarkers—GFAP (Glial Fibrillary Acidic Protein), UCH-L1 …

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Dementia
Reply to “Clarifying the Moderating Role of Socioeconomic Status on Amyloid-Related Gray Matter Atrophy”

by myneuronews October 7, 2025

by myneuronews October 7, 2025

Study Overview This study addresses the complex interactions between socioeconomic status (SES) and the neurobiological …

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Traumatic brain injury
Heading in Soccer Players and Neurologic Outcomes

by myneuronews October 6, 2025

by myneuronews October 6, 2025

Neurologic Impacts of Heading Heading the ball is a fundamental skill in soccer, yet it …

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Dementia
Robust Extrapolated Semi-Solid Magnetization Transfer Reference Fitting for Quantitative Amide Proton Transfer Imaging at 3 T: Application to Patients With Mild Cognitive Impairment and Mild Dementia

by myneuronews October 3, 2025

by myneuronews October 3, 2025

Study Overview This study focuses on advancing the understanding of quantitative Amide Proton Transfer (APT) …

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Dementia
Albuminuria is associated with increased risk of dementia, independent of eGFR: The SCREAM project

by myneuronews September 23, 2025

by myneuronews September 23, 2025

Association Between Albuminuria and Dementia Risk Recent investigations have illuminated the relationship between albuminuria, a …

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Dementia
Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

by myneuronews September 19, 2025

by myneuronews September 19, 2025

Study Overview The investigation centered on understanding the critical role of TDP-43, a protein associated …

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Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …

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Dementia
Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants

by myneuronews September 7, 2025

by myneuronews September 7, 2025

Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in …

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Dementia
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression …

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Traumatic brain injury
Quantitative video analysis of head acceleration events: a review

by myneuronews September 5, 2025

by myneuronews September 5, 2025

Study Overview This article presents a comprehensive review of the techniques and findings surrounding the …

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Beyond the Concussion: Cerebral Venous Thrombosis Following Mild-to-Moderate Traumatic Brain Injury
Cerebral venous sinus thrombosis (CVST) accounts for a small proportion of strokes. Still, it carries meaningful clinical impact, classically linked to systemic prothrombotic conditions, hormonal influences, and severe traumatic brain injury (TBI). However, with advances in neuroimaging, it's now evident that trauma-related CVST (tCVST) can also complicate mild to moderate head injuries even in the […]
Network co-activation relates to executive function following pediatric traumatic brain injury
CONCLUSIONS: Findings illustrate the implications of disrupted downregulation of the default mode network by the SN following pediatric brain injury. They also demonstrate how disruption in functional connectivity may underlie poor executive function after childhood traumatic brain injury.
Monitoring the lateral ventricles in the presence of intracranial hemorrhage using automated dual segmentation
CONCLUSIONS: Automated dual segmentation of lateral ventricles and ICH using deep learning provides a reliable method to monitor TBI severity over time. The approach yielded clinically relevant information, including ICH and lateral ventricle volume changes across sessions. This approach offers an efficient analysis of CT images in ICH and particularly patients that develop IVH.
Quality of Life, Self-Reported Cognitive Difficulties, and Performance-Based Cognitive Problems in Multiple Sclerosis: What's Sleep Got to Do With It?
CONCLUSIONS: Poor sleep quality was not associated with performance-based cognitive functioning but was associated with greater self-reported cognitive difficulties. After accounting for disease progression, depression, and fatigue, poor sleep quality was significantly predictive of both Symptoms and Fatigue QoL.
Parent and Child Agreement of Brain Injury Perceptions Following Pediatric Concussion
CONCLUSIONS: Parent-child agreement regarding brain injury perceptions following a pediatric concussion was low (13%), reflecting the importance of assessing and then addressing parent and child perceptions individually in pediatric concussion management.