Tag:

neurodegenerative diseases

Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Traumatic brain injury
The Acute Effects of Non-concussive Head Impacts on Brain Microstructure, Chemistry and Function in Male Soccer Players: A Pilot Randomised Controlled Trial

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Study Overview This pilot randomized controlled trial set out to investigate the immediate effects of …

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Functional neurological disorders
Diagnostic Challenges in Creutzfeldt-Jakob Disease: A Case Report of an Atypical Presentation

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Clinical Presentation of Atypical Cases The clinical presentation of atypical cases of Creutzfeldt-Jakob disease (CJD) …

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Functional neurological disorders
Diagnostic Challenges in Creutzfeldt-Jakob Disease: A Case Report of an Atypical Presentation

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Atypical Clinical Presentation Creutzfeldt-Jakob Disease (CJD), a rare and progressively fatal neurodegenerative disorder, is primarily …

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Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease The role of insulin signalling pathways in Alzheimer’s disease …

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Functional neurological disorders
Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

by myneuronews June 16, 2025

by myneuronews June 16, 2025

Insulin Signalling Pathways in Alzheimer’s Disease Insulin signalling pathways play a crucial role in numerous …

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Dementia
Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

by myneuronews June 14, 2025

by myneuronews June 14, 2025

Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

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Functional neurological disorders
Connectogram-COH: A Coherence-Based Time-Graph Representation for EEG-Based Alzheimer’s Disease Detection

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Coherence-Based Time-Graph Representation The study introduces an innovative approach for representing and analyzing EEG data …

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Functional neurological disorders
Connectogram-COH: A Coherence-Based Time-Graph Representation for EEG-Based Alzheimer’s Disease Detection

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Coherence-Based Time-Graph Methodology The study employs a coherence-based time-graph methodology to create a novel representation …

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Dementia
One size does not fit all: how type of menopause and hormone therapy matters for brain health

by myneuronews June 9, 2025

by myneuronews June 9, 2025

Menopause Types and Their Impact Menopause is a significant transition in a woman’s life, marked …

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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that…
Collaborative Community Support for People Impacted by Dementia: A Social Return on Investment Analysis
Study Overview This research focuses on understanding the impact of a community-based support program designed…
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Cognitive Fatigue in Pediatric Populations Cognitive fatigue is a significant concern in pediatric populations, particularly…
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the…
ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Study Overview The study focuses on enhancing the accuracy of brain lesion parcellation, a crucial…

Substrate-selective COX-2 inhibition by IMMA attenuates posttraumatic headache via endocannabinoid modulation and neuroinflammatory suppression
CONCLUSION: IMMA effectively attenuates neuroinflammation and pain hypersensitivity in the acute phase of PTH through a distinct mechanism that preserves endocannabinoid tone without suppressing physiological prostaglandins. While these results highlight its promise as a novel therapeutic strategy, further studies are warranted to determine its efficacy during the chronic phase of PTH and across anatomically targeted […]
Intensive exposure therapy for individuals with persistent concussion symptoms following concussion: a replicated single-case experimental design (SCED) study
CONCLUSIONS: The findings of this study further confirmed the efficacy for this intensive exposure therapy for PCS, adding further evidence for exposure therapy in this patient population. Replication in other samples is needed.
Sensory integration processes characterize concussed athletes with balance deficits
Impaired postural control constitutes a major symptom after mild traumatic brain injuries (mTBI/sport-related concussions (SRC)). In order to uphold cognition and behavior during pathological situations, individuals may be characterized by neuronal upregulation. Because postural control necessitates the integration of sensory information within somatosensory (/parietal) cortices, we investigated the hypothesis that athletes with ongoing symptoms after […]
Methods of humane killing of laboratory fish: FELASA Working Group recommendations
As commissioned by the Federation of European Laboratory Animal Science Associations, these working group recommendations define the requirements to achieve the humane killing of fish, compare methods of killing, recommend methods of killing depending on context, and detail protocols leading to good practice. With a review of current practices in a fish laboratory and available […]
Exercise-Induced Symptom Exacerbation and Adverse Events in Moderate-to-Severe Traumatic Brain Injury
CONCLUSIONS: CRF and HLM exertional testing in the early subacute phase of recovery following moderate-to-severe TBI appears to be safe, with low rates of symptom exacerbation and adverse events identified.