Tag:

neurodegenerative diseases

Dementia
Discrepancies between CSF biomarker and PET determinations of elevated brain amyloid and their prognostic significance

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Study Overview The ongoing challenge of accurately diagnosing Alzheimer’s disease and other neurodegenerative conditions has …

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Functional neurological disorders
Functional connectome integration observed after antispastic epidural cervical spinal cord stimulation in a patient with TBI-induced disorder of consciousness: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Functional Connectome Integration Recent advances in neuroimaging have enhanced our understanding of how different brain …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanisms of Wogonin Action Wogonin, a naturally occurring flavonoid derived from the plant Scutellaria baicalensis, …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanism of Wogonin Action Wogonin, a naturally occurring flavonoid derived from the plant Scutellaria baicalensis, …

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Functional neurological disorders
Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical macrostructural alterations The study of cortical macrostructural alterations in individuals with isolated rapid eye …

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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

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Functional neurological disorders
Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical changes in rapid eye movement sleep behavior disorder Recent studies have highlighted significant alterations …

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Functional neurological disorders
Unveiling cortical criticality changes along the prodromal to the overt continuum of alpha-synucleinopathy

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Cortical Criticality in Alpha-Synucleinopathy Recent research into alpha-synucleinopathy—disorders associated with the abnormal accumulation of the …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Traumatic brain injury
Biomarker evidence of neurodegeneration in mid-life former rugby players

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurodegeneration Biomarkers Biomarkers indicative of neurodegeneration are crucial for understanding the underlying processes affecting brain …

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Patient-reported preferences for sleep apnoea treatments in an Australian community sample
Study Overview The research aimed to explore the preferences of individuals diagnosed with sleep apnoea…
Long-term dementia risk following electroconvulsive therapy: A GRADE-assessed systematic review and meta-analysis
Study Overview Electroconvulsive therapy (ECT) has been a significant intervention in the treatment of severe…
Association Between Intraindividual Variability in Cognitive Performance and White Matter Organisation in Chronic Mild Traumatic Brain Injury
Study Overview This research delves into the relationship between cognitive performance variability and white matter…
Longitudinal gait changes in functional neurological disorder: A 12-month prospective study
Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a complex challenge for both patients…
SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
Study Overview The SaVeBRAIN.Kids initiative is a comprehensive research project focused on addressing the significant…

Pediatric concussion characteristics differ based on age
CONCLUSIONS: The results build on previous studies showing that younger pediatric patients sustain concussions mostly from non-sports mechanisms and endorse fewer symptoms which could be due to lower severity of injury and/or primarily relying on parent reporting of observable concussion symptoms. Pediatric concussion mechanism and presentation differ across ages, emphasizing the importance of age-appropriate symptom […]
Glymphatic system and mild traumatic brain injury: a mini review
Since the discovery of the glymphatic system in 2012, research on this brain-wide fluid exchange pathway has focused on understanding its role in different neurological diseases. Mild traumatic brain injury (mTBI) is a prevalent, yet often undiagnosed, condition that increases the risk of developing debilitating neurodegenerative diseases. mTBI may lead to impaired glymphatic system function […]
Subtle ocular motor deficits in people with chronic whiplash associated disorder compared to healthy controls
INTRODUCTION: More than 50% of people who are diagnosed with whiplash-associated disorder (WAD) will report symptoms 12 months and beyond after their initial onset. However, many signs and symptoms, such as dizziness, emotional lability, confusion, ocular movement abnormalities, and balance deficits, may not be directly attributed to the cervical spine and may be more consistent […]
Symptom burden in the first four years following hospitalization after mild traumatic brain injury
CONCLUSIONS: Clinicians should be alert to the long-term presence of multiple symptoms following hospitalization after mTBI, as these affect a significant proportion of individuals and are associated with poorer outcomes.
Neither American Football Playing Position Nor Total Years Playing Football Are Associated with Neurobehavioral Health Outcomes: An NFL-LONG Study
Years playing American football and primary playing position are often used to estimate concussion exposure. We examined associations between playing position and total years played with concussion history and neurobehavioral outcomes among former (N = 1544) National Football League players in the NFL-LONG study. Outcomes included the PROMIS Cognitive, Depression, and Anxiety T-scores, and Neuro-QOL […]