Tag:

neurodegenerative diseases

Traumatic brain injury
Letter: Mild Traumatic Brain Injury in Older Adults: Recovery Course and Insights on Early Predictors of Outcome

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Recovery Patterns in Older Adults The recovery patterns following mild traumatic brain injury (mTBI) in …

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Dementia
Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis

by myneuronews August 7, 2025

by myneuronews August 7, 2025

Study Overview The research aimed to investigate the role of TDP-43 accumulation in the progression …

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Dementia
Exploring the mediating role of the plasma lipidome in the pathway from the gut microbiota to dementia: a Mendelian randomization study

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Study Overview This research investigates the intricate relationships between gut microbiota, plasma lipid profiles, and …

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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Traumatic brain injury
Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Historical Context of Neurological Disorders The understanding of neurological disorders in Boxers has evolved significantly …

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Traumatic brain injury
A voice for Tom: an urgent call for more research into neurodegenerative disease and contact sport

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Neurodegenerative Disease and Contact Sports Neurodegenerative diseases represent a broad category of disorders characterized by …

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Traumatic brain injury
Cognitive-Communication Rehabilitation after Brain Injuries

by myneuronews July 28, 2025

by myneuronews July 28, 2025

Cognitive Communication Challenges Cognitive communication challenges arise when individuals experience difficulties in the processes that …

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Dementia
Unveiling blood biomarkers for neuronal hyperplasticity: Insights from AD molecular subtyping, a comprehensive review

by myneuronews July 25, 2025

by myneuronews July 25, 2025

Study Overview The research focuses on the exploration of blood biomarkers that indicate neuronal hyperplasticity, …

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Functional neurological disorders
Integrated in silico identification of cholinesterase inhibitors from Nyctanthes arbor-tristis

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Identification of Cholinesterase Inhibitors Research has increasingly focused on the potential therapeutic roles of various …

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Dementia
Embracing the Modern Biochemistry of Brain Metabolism

by myneuronews July 21, 2025

by myneuronews July 21, 2025

Understanding Brain Metabolism The brain is an extraordinarily energy-demanding organ, consuming approximately 20% of the …

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Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis
Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in…
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective
Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders…
DCPat-XFE: an explainable EEG model for psychogenic nonepileptic seizure detection
Study Summary The study presents the DCPat-XFE model, designed to enhance the detection of psychogenic…
Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
Study Overview The focus of this scoping review is to explore the prevalence of vestibular…
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
Study Overview The article investigates the relationship between engagement in sports and physical activities and…

Artificial Intelligence in Traumatic Brain Injury: A Systematic Review of Prognostic, Diagnostic, and Monitoring Applications
Traumatic brain injury (TBI) remains a leading cause of death and disability worldwide, with outcomes that are highly heterogeneous and difficult to predict using conventional clinical tools. Artificial intelligence (AI) has emerged as a promising approach to enhance diagnosis, prognostication, and management of TBI across diverse care settings. Following PRISMA guidelines, a comprehensive search of […]
Transcranial direct current stimulation (tDCS) in conscious mice: a refined method for repetitive applications without restraint
Transcranial direct current stimulation (tDCS) for painless, non-invasive brain stimulation is a promising approach to enhance recovery after stroke. However, the precise molecular and cellular mechanisms underlying the effects of tDCS remain unclear, impeding its use in humans and necessitating research in experimental animals. Unlike humans, who receive tDCS fully awake, experimental models of tDCS […]
A study on the association of apolipoprotein E with oxidative stress markers, neurological function, and cognitive impairment following traumatic brain injury
CONCLUSION: ApoE exhibits an injury-severity-dependent increase during the early stage of TBI, and its levels are closely associated with oxidative stress imbalance and cognitive impairment. These findings suggest that ApoE may play a critical role in both the pathological progression and neural repair following TBI.
A comprehensive review on adaptive plasticity and recovery mechanisms post-acquired brain injury
Adaptive plasticity, the brain's ability to reorganize and form new neural connections after injury, is crucial for recovery following acquired brain injury (ABI). This process involves axonal sprouting, dendritic remodeling, and neurogenesis, which restore neural connections and compensate for lost functions. While neuroinflammation and reactive astrocytes aid tissue repair, optimizing these responses to minimize secondary […]
Sex differences in fixational eye movements following concussion
Recent research supports impairments in fixational eye movements (FEMs), small motions of the eye that occur during periods when gaze is maintained on a fixed target, as an objective biomarker of concussion. Preliminary work has demonstrated that fixational saccades are larger following a concussion; however, sex differences in FEMs and fixational saccades have not been […]