Tag:

neuroinflammation

Traumatic brain injury
A Semi-Automated and Unbiased Microglia Morphology Analysis Following Mild Traumatic Brain Injury in Rats

by myneuronews September 13, 2025

by myneuronews September 13, 2025

Study Overview This study investigates the morphological changes in microglia, the immune cells of the …

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Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Dementia
Estimated Glucose Disposal Rate and Risk of Stroke and Dementia in Nondiabetics: A UK Biobank Prospective Cohort Study

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview The investigation centered around the relationship between glucose disposal rate and the risk …

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Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …

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Dementia
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center Clinical Core …

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Traumatic brain injury
Progressive lifespan modifications in the corpus callosum following a single concussion in juvenile male mice monitored by diffusion MRI

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Study Overview The investigation aimed to explore the long-term impacts of a single concussion on …

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Traumatic brain injury
A prolyl oligopeptidase ligand blocks memory deficit in a repeated mild traumatic brain injury model

by myneuronews September 8, 2025

by myneuronews September 8, 2025

Study Overview This research investigates the role of a prolyl oligopeptidase (POP) ligand in the …

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Dementia
Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants

by myneuronews September 7, 2025

by myneuronews September 7, 2025

Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in …

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Dementia
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression …

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Traumatic brain injury
Probiotics Co-administered with LCM Enhance Antiepileptic Efficacy in the Experimental Post-traumatic Epilepsy Model

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview The investigation focused on the synergistic effects of probiotics when administered alongside levetiracetam …

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Severe Headache in a Child With Rickettsial Infection: A Case Report
Case Presentation A previously healthy 10-year-old boy was brought to the pediatric emergency department due…
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids
Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease…
How Neurologists Combine Clinical Signs and Subjective Factors to Diagnose Epileptic and Functional Seizures: Insights From Seizure Video Analysis
Diagnostic Approaches in Epilepsy and Seizures The diagnosis of epilepsy and seizures is a complex…
Active Rehabilitation Following Acute Mild Traumatic Brain Injury: A Systematic Review
Active Rehabilitation Approaches Active rehabilitation is a crucial component in the recovery process following an…
Connecting the Dots: The Role of Pediatric Concussion on Pubertal Hormones and Psychological Health
Pediatric Concussions: Overview and Impact Pediatric concussions are a significant public health concern, with increasing…

The cumulative effects of a collegiate athletic career on general health measures: findings from the CARE Consortium
CONCLUSIONS: Lifetime concussion history is associated with self-reported health outcomes at institutional-exit, though small effect sizes suggest limited clinical consequence. Higher contact-exposure sports and increased YoP were associated with improved scores on some clinical measures. Further longitudinal monitoring is encouraged to evaluate health-related changes over time, to support student-athletes as they transition out of collegiate […]
Efficacy of Methylphenidate in Patients With Brain Disease: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis evaluated the efficacy and safety of methylphenidate in patients with brain disease. A comprehensive search up to November 4, 2024 identified 33 randomized controlled trials involving 1,369 participants with traumatic brain injury (TBI), stroke, Parkinson's disease (PD), Alzheimer's disease (AD), other dementias, and multiple sclerosis. Methylphenidate was administered at 10-80 […]
Symptoms of Allodynia and Pain Thresholds Amongst Those with Acute Post-Traumatic Headache Attributed to Mild Traumatic Brain Injury: A Prospective, Longitudinal Study
Background Post-traumatic headache (PTH) is a common acute and persistent symptom following mild traumatic brain injury (mTBI). Symptoms of cutaneous allodynia and presence of nociceptive sensitization might be associated with acute PTH and its persistence. The objectives of this study were to compare allodynia symptoms and cutaneous heat pain thresholds amongst males and females with […]
Blast-Related Mild Traumatic Brain Injury: Case Report Highlighting the Long-Term Neurocognitive Sequelae Following Blast Exposure in Veterans
Traumatic brain injury (TBI) remains a significant public health concern, particularly among military service members exposed to blast-related trauma. While mild TBIs often resolve within weeks, a subset of patients may experience lifelong, persistent, debilitating symptoms. We report a case of a previously healthy male combat medic who sustained a blast-related traumatic brain injury during […]
Biomechanical injury risk analysis of a child dummy under cricket ball impacts: A finite element study
Children, while playing cricket, may get exposed to impact-related injuries. Most available studies have been done on adult players. Pediatric biomechanics concerning cricket ball impacts have been unexamined, supported by assumptions and surrogate models. This research used a finite element model of a child dummy, a ball, and a steel chair. Four conditions based on […]