Tag:

neuroinflammation

Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes in Glial Scarring After a traumatic brain injury (TBI), the central nervous system …

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Dementia
Divergent and convergent TMEM106B pathology in murine models of neurodegeneration and human disease

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Pathological Roles of Tmem106b in Neurodegeneration The involvement of TMEM106B in neurodegenerative diseases is a …

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Traumatic brain injury
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury

by myneuronews August 9, 2025

by myneuronews August 9, 2025

Biochemical Changes During Glial Scar Formation After a traumatic brain injury (TBI), the brain undergoes …

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Traumatic brain injury
Letter: Mild Traumatic Brain Injury in Older Adults: Recovery Course and Insights on Early Predictors of Outcome

by myneuronews August 8, 2025

by myneuronews August 8, 2025

Recovery Patterns in Older Adults The recovery patterns following mild traumatic brain injury (mTBI) in …

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Traumatic brain injury
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model

by myneuronews August 6, 2025

by myneuronews August 6, 2025

Study Overview The research focuses on the development of a specialized apparatus designed to replicate …

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Functional neurological disorders
AAV-based gene therapy ameliorates neurological deficits in a mouse model of childhood-onset neurodegeneration with cerebellar atrophy (CONDCA)

by myneuronews August 4, 2025

by myneuronews August 4, 2025

Study Summary The study investigates the efficacy of adeno-associated virus (AAV)-based gene therapy in a …

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Traumatic brain injury
Knockout of indoleamine 2,3-dioxygenase 1 gene expression improves depressive and anxiety-like phenotypes in a murine model of mild traumatic brain injury

by myneuronews August 3, 2025

by myneuronews August 3, 2025

Study Overview The research investigates the effects of knocking out the expression of the indoleamine …

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Dementia
Environmental aluminum exposure and Alzheimer’s disease risk: Evidence from a systematic review and meta-analysis

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Study Overview The investigation into the potential link between environmental aluminum exposure and the risk …

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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Traumatic brain injury
Neurological Disorders and Clinical Progression in Boxers from the 20th Century: A Narrative Review

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Historical Context of Neurological Disorders The understanding of neurological disorders in Boxers has evolved significantly …

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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that…
Collaborative Community Support for People Impacted by Dementia: A Social Return on Investment Analysis
Study Overview This research focuses on understanding the impact of a community-based support program designed…
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Cognitive Fatigue in Pediatric Populations Cognitive fatigue is a significant concern in pediatric populations, particularly…
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the…
ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Study Overview The study focuses on enhancing the accuracy of brain lesion parcellation, a crucial…

A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Acquired Brain Injuries (ABIs) cause long-term disruption to young individuals' development. Persistent cognitive fatigue is a commonly reported sequela following pediatric ABI. Currently, there are no evidence-based interventions targeting cognitive fatigue post-ABI amongst pediatric patients. The current systematic review and meta-analysis aimed to review research on the efficacy of pharmacological and non-pharmacological interventions for cognitive […]
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
CONCLUSION: Serum TMAO levels were significantly elevated in PTSD patients comorbid with TBI and were closely associated with PTSD severity. Furthermore, TMAO may aid in the early identification of high-risk, severe PTSD patients following TBI, thus helping to optimize intervention strategies.
ENIGMA's advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Cortical parcellation is a critical step in several neuroimaging pipelines, yet even in high quality images without pathology, errors are common. For patients with moderate to severe traumatic brain injury (ms-TBI), typical parcellation errors can be exacerbated by focal pathology impacting cortical regions. Careful visual quality checking (QC) of parcellation images of ms-TBI patients should […]
Knowledge and attitudes of concussion and chronic traumatic encephalopathy amongst a sample of non-professional rugby players
CONCLUSIONS: Non-professional rugby players are generally knowledgeable about concussion. However, some gaps in their knowledge relating to coma and the course of symptoms of concussion were identified. Unsafe attitudes, particularly among school players, need to be addressed. Non-professional rugby players are interested in further education about CTE.
Multi-modal proton and sodium MRI for outcome prediction in mild traumatic brain injury
CONCLUSIONS: We identified independent, dynamic, metabolic and ionic changes, with choline and creatine from spectroscopy fulfilling the most criteria for a clinical biomarker.