Gut microbiota and gut-derived metabolites in defining multiple sclerosis phenotypic continuum
Gut Microbiota Role The gut microbiota plays a fundamental part in maintaining human health, impacting various physiological processes through the […]
Valsartan Repurposing to Mitigate Autoimmune Encephalomyelitis via ACE2/Ang1-7/MasR Axis Pathway Cognitive and Neuroinflammation Modulation; an Experimental and Chem-bio-informatics Study
Therapeutic Targeting of ACE2/Ang1-7/MasR Axis The ACE2/Ang1-7/MasR axis represents a critical pathway in the regulation of cardiovascular and neurological functions,
Ferritin-ApoE nanocarrier for targeted therapy of neuromyelitis optica spectrum disorder in mice
Study Overview The investigation centered on the development and assessment of a specialized nanocarrier system combining ferritin and apolipoprotein E
Glial Heme Oxygenase-1 Regulates Neuroinflammation and Cerebrovascular Function After Mild Traumatic Brain Injury
Role of Heme Oxygenase-1 in Neuroinflammation Heme oxygenase-1 (HO-1) is an enzyme that plays a crucial role in the breakdown
Valsartan Repurposing to Mitigate Autoimmune Encephalomyelitis via ACE2/Ang1-7/MasR Axis Pathway Cognitive and Neuroinflammation Modulation; an Experimental and Chem-bio-informatics Study
Study Overview The research aimed at exploring the potential repurposing of valsartan, a medication primarily indicated for hypertension and heart
Honokiol attenuates neuroinflammation and enhances remyelination in mouse models of multiple sclerosis through PPARγ-mediated ERK/AKT signalling
Study Overview This research investigates the impact of honokiol, a natural compound derived from magnolia trees, on neuroinflammation and remyelination
Multiple sclerosis as an asynchronous neuroinflammatory system
Neuroinflammatory Mechanisms Multiple sclerosis (MS) is characterized by complex neuroinflammatory processes that contribute to its pathophysiology. Central to MS is
Multiple sclerosis as an asynchronous neuroinflammatory system Read Post »
Smoking accelerates immunosenescence in multiple sclerosis
Impact of Smoking on Immunosenescence Smoking has been associated with a range of health consequences, but its specific impact on
Smoking accelerates immunosenescence in multiple sclerosis Read Post »
Honokiol attenuates neuroinflammation and enhances remyelination in mouse models of multiple sclerosis through PPARγ-mediated ERK/AKT signalling
Study Overview The investigation aimed to assess the therapeutic potential of honokiol, a compound derived from the magnolia plant, in
Microglia-mediated neuroinflammation and demyelination contribute to pain and social behavioral deficits after spared nerve injury
Microglia and Neuroinflammation Microglia, the resident immune cells of the central nervous system, play a crucial role in maintaining brain